Grant ID RR230072
Awarded On August 16, 2023
Title Recruitment of First-Time, Tenure-Track Faculty Members
Program CPRIT Scholar
Award Mechanism Recruitment of First-Time, Tenure-Track Faculty Members
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Simon Eschweiler
Cancer Sites Lung and Bronchus, Ovary, Skin
Contracted Amount $2,000,000
Summary of Goals and Objectives

Immunotherapies have become crucial treatment options for a variety of cancer types. However, fewer than 30% of people respond to a given therapy. Hence, as low efficacy and widespread immune-related toxicity severely limit both treatment efficacy and combination therapy options, there is urgent need to develop novel immunotherapy targets with an improved efficacy and safety profile. Thus, the overall goal of this application is to devise and test novel immunotherapeutic strategies through mechanism-guided approaches. Accordingly, the objectives of my proposal are to (i) assess the clinical validly of novel cellular targets of cancer immunotherapy, (ii) develop and/or test immunotherapies th...

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