Grant ID RR230054
Awarded On August 16, 2023
Title Recruitment of First-Time, Tenure-Track Faculty Members
Program CPRIT Scholar
Award Mechanism Recruitment of First-Time, Tenure-Track Faculty Members
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Xiaofeng Qi
Cancer Sites Breast, Pancreas, Skin
Contracted Amount $2,000,000
Summary of Goals and Objectives

In recent years, many studies demonstrated that harnessing the immune system has great potential and promising outcomes for cancer treatment. However, immune regulation within the tumor microenvironment (TME) is highly complicated and involves multiple factors, making the development of effective cancer immunotherapies challenging. To address these difficulties, my research will focus on critical proteins located on the T cell membrane, including newly identified checkpoints, chemokine receptors, Ca2+ channels, and amino acid transporters, that play essential roles in immune regulation within the TME. Using state-of-the-art bioc...

Read More