Grant ID RR230053
Awarded On August 16, 2023
Title Recruitment of First-Time, Tenure-Track Faculty Members
Program CPRIT Scholar
Award Mechanism Recruitment of First-Time, Tenure-Track Faculty Members
Institution/Organization The University of Texas at Dallas
Principal Investigator/Program Director Chen Cao
Cancer Sites All Sites
Contracted Amount $1,800,000
Summary of Goals and Objectives

The interactions between cellular compositions of the tumor microenvironment (TME) are increasingly recognized as major determinants of tumor progression. Recently, the rapid development of single cell sequencing technologies has revolutionized our understanding of the biological characteristics and dynamics of the entire tumor ecosystem, such as mechanisms of intratumoral and intertumoral heterogeneity. However, current scRNASeq studies generating detailed catalogues of cell types and states work from the top down to study how cell components interact in TME, lacking access to tweak and quantify the contributions of different cell types in normal and malignant tissue organizations. To lever...

Read More