Grant ID RR210066
Awarded On August 18, 2021
Title Recruitment of First-Time, Tenure-Track Faculty Members
Program CPRIT Scholar
Award Mechanism Recruitment of First-Time, Tenure-Track Faculty Members
Institution/Organization Baylor College of Medicine
Principal Investigator/Program Director Chad Johnston
Cancer Sites Colorectal, Gallbladder, Liver and Intrahepatic Bile Duct
Contracted Amount $2,000,000
Summary of Goals and Objectives

The goal of this research is to access precision pharmaceuticals that can edit the microbiome to prevent microbe-associated cancers and improve therapeutic efficacy. In the last decade, the revelation that specific bacteria impact the occurrence, prognosis, and treatment of cancer has exposed a need for drugs that can target problematic microbes without compromising communities that are essential for patient health and effective immuno-therapies. In Nature, bacteria achieve this kind of selective community editing using natural products: small molecules that feature chemical structures and biological activities that have been honed through millions of years of evolution.

Over the last decade...

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