Grant ID RR210007
Awarded On November 18, 2020
Title Recruitment of Established Investigators
Program CPRIT Scholar
Award Mechanism Recruitment of Established Investigators
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Bissan Al-Lazikani
Cancer Sites All Sites
Contracted Amount $6,000,000
Summary of Goals and Objectives

This proposal is to establish an Artificial Intelligence (AI)-enabled Rapid Reverse-Translation Engine within MD Anderson. This will form the foundation of an innovative Discovery Data Science capability as part of a broader Data Science Initiative.

It will enable:

  1. Discovering patient cohort-specific, multimodal disease mechanism maps that better inform drug re-purposing and novel therapeutic target identification
  2. Discovering multimodal prognostic, response biomarkers or adverse-event predictors
  3. Closing gaps in the translation of such discoveries from hypotheses to the clinic via innovative, AI-guided, translation decision-support

I will:

  1. Develop a Discovery Knowledge-C...

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