Grant ID RP230431
Awarded On August 16, 2023
Title Unraveling the Therapeutic Potential of Osr1 Overexpression in Hepatocellular Carcinoma Management
Program Academic Research
Award Mechanism TREC: Pilot Study Award
Institution/Organization Texas A&M University
Principal Investigator/Program Director Linglin Xie
Cancer Sites Gallbladder, Liver and Intrahepatic Bile Duct
Contracted Amount $200,000
Lay Summary

Liver cancer, particularly hepatocellular carcinoma (HCC), is a rapidly growing cancer in the US, with a poor prognosis and limited treatment options. Texas has a higher incidence rate of liver cancer compared to the national average, likely due to the high prevalence of risk factors such as viral infections, excessive alcohol consumption, and fatty liver, as well as a large population of Hispanics and African Americans who are at higher risk. In addition, rural areas of Texas face challenges with delayed diagnosis and treatment due to a shortage of healthcare professionals and facilities. Conventional treatments for liver cancer often have low efficacy and severe side effects, necessitating...

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