Grant ID | RP220021 |
Awarded On | February 16, 2022 |
Title | Monitoring of Field Effects for the Detection of Bladder Cancer |
Program | Academic Research |
Award Mechanism | Individual Investigator Research Awards for Prevention and Early Detection |
Institution/Organization | The University of Texas M.D. Anderson Cancer Center |
Principal Investigator/Program Director | Bogdan Czerniak |
Cancer Sites | Bladder |
Contracted Amount | $1,993,172 |
Lay Summary |
In this grant we propose whole-organ-based genomic characterization of field effects and how they evolve to clinically aggressive bladder cancer complemented by the validation studies of novel multi-colored Quartet FISH and voided urine exome sequencing. These studies will provide novel markers for diagnostic monitoring of bladder cancer including its recurrence and progression by a non-invasive approach in voided urine. When completed these studies will positively impact the clinical practice and management of patients affected by this common cancer. |