Grant ID RP220021
Awarded On February 16, 2022
Title Monitoring of Field Effects for the Detection of Bladder Cancer
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Prevention and Early Detection
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Bogdan Czerniak
Cancer Sites Bladder
Contracted Amount $1,993,172
Lay Summary

In this grant we propose whole-organ-based genomic characterization of field effects and how they evolve to clinically aggressive bladder cancer complemented by the validation studies of novel multi-colored Quartet FISH and voided urine exome sequencing. These studies will provide novel markers for diagnostic monitoring of bladder cancer including its recurrence and progression by a non-invasive approach in voided urine. When completed these studies will positively impact the clinical practice and management of patients affected by this common cancer.