Grant ID RP220011
Awarded On February 16, 2022
Title A randomized, controlled trial comparing the immunogenicity of 2 doses vs 3 doses of the 9-valent HPV vaccine in females 27-45 years of age
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Prevention and Early Detection
Institution/Organization The University of Texas Medical Branch at Galveston
Principal Investigator/Program Director Abbey Berenson
Cancer Sites Cervix Uteri
Contracted Amount $1,986,984
Lay Summary

HPV is associated with cancer of the cervix, vulva, vagina, anus, oropharynx, and penis. Fortunately, a vaccine is available which has the potential to markedly reduce, or even eliminate, these cancers. The CDC recommends that it be administered at age 11-12 years although it may be given as young as 9. For those not vaccinated at a younger age, it was originally recommended up to age 26. This was recently extended to age 45. The CDC estimates that 80% of those eligible need to be completely vaccinated to reach herd immunity. However, this goal remains out-of-reach as vaccine completion rates are extremely low in the US, especially among adults. One reason for this is that multiple doses are...

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