Grant ID RP210165
Awarded On August 18, 2021
Title Rapid Point-of-care Detection of Ovarian Cancer Biomarkers Using a Common Thermometer for Low-Resource Settings
Program Academic Research
Award Mechanism High Impact/High Risk
Institution/Organization The University of Texas at El Paso
Principal Investigator/Program Director Xiujun Li
Cancer Sites Ovary
Contracted Amount $249,999
Lay Summary

There are 239,000 new cases of ovarian cancer and 140,000 deaths due to ovarian cancer each year worldwide. However, there are no suitable screening modalities for ovarian cancers and repeated imaging and monitoring of CA125 (a biomarker) levels are often needed to triage equivocal ovarian masses. These detection methods, however, lack accuracy for detecting early-stage asymptomatic disease and, as a result, ovarian cancer is typically diagnosed at an advanced stage. Cancer biomarker detection plays a crucial role in early ovarian cancer diagnosis, treatment, and risk assessment, whereas current immunoassay-based detection methods for ovarian cancer biomarkers require costly and bulky instru...

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