|Awarded On||February 19, 2020|
|Title||Spatial Profiling of Tumor-Immune Microenvironment by Multiplexed Single- Cell Imaging Mass Cytometry|
|Award Mechanism||Individual Investigator|
|Institution/Organization||Baylor College of Medicine|
|Principal Investigator/Program Director||Hyun-Sung Lee|
|Cancer Sites||Lung and Bronchus|
Malignant pleural mesothelioma (MPM) is a deadly and distressing cancer of the pleura, which is a lining around the lungs that is usually acquired by inhaling asbestos fibers. Even though there are now laws in the US limiting asbestos use, many people have had exposure to asbestos in other countries and through construction projects of older structures; often MPM develops decades after exposure. In fact, Texas has the 4th highest death rate from MPM in the nation. Treatment for mesothelioma has included surgery, chemotherapy, and radiation, but these measures are not very effective. The median survival rate is usually measured in months, with the five-year survival rate at only 10%. A new ho...