|Awarded On||August 24, 2018|
|Title||Microfluidic Cancer Assay for Liquid Biopsies and Early Detection|
|Award Mechanism||High Impact/High Risk|
|Institution/Organization||Texas Tech University|
|Principal Investigator/Program Director||Dimitri Pappas|
|Cancer Sites||All Sites|
There is a growing need to detect cancer early. In leukemias, the presence of cancer cells in the blood is indicative of poor outcomes. In solid tumors, cancer cells shed from the tumor enter the blood stream and spread to other parts of the body. The presence of cancer cells in blood, and other bodily fluids, can be used as a diagnostic called a "liquid biopsy." Currently, detection of cancer cells in blood requires extensive knowledge of the cancer type prior to detection. Physical methods to isolate cancer cells cannot distinguish clearly between cancer and normal cells. Methods involving antibody capture of cells often miss key groups of cancer cells, as there is currentl...