Grant ID RP180031
Awarded On February 21, 2018
Title Imaging of biochemical alterations in human breast malignancy using CEST-MRI
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Elena Vinogradov
Cancer Sites Breast
Contracted Amount $900,000
Lay Summary

Due to progress in detection and treatment of breast cancer, its mortality rate has steadily declined. Widespread adoption of mammography and routine screening has been credited for this decline, as it has a vital role in detection and evaluation of breast cancer. But the breast cancer management has recently come under scrutiny, due to concerns about increased number of unnecessary biopsies and unjustifiably aggressive treatments. Magnetic resonance imaging (MRI) is widely utilized for radiological surveillance due to its superb sensitivity. However, MRI suffers from lower specificity and cannot provide information on biochemical level, thus failing to fully characterize breast lesions....

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