Grant ID RP170564
Awarded On November 16, 2016
Title Super-resolution imaging of tumor angiogenesis in deep tissue with high specificity and sensitivity
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas at Arlington
Principal Investigator/Program Director Baohong Yuan
Cancer Sites Breast, Colorectal, Head and Neck, Ovary, Prostate, Skin, Thyroid, Vagina
Contracted Amount $900,000
Lay Summary

Tumor angiogenesis is the growth of new blood vessels to provide nutrients and oxygen for tumor growth. Without angiogenesis, tumor cannot grow beyond 1-2 mm and the possibility of cancer metastasis is significantly reduced. Angiogenic blood vessels in a cancerous tumor have many unique features compared with in normal tissues or benign lesions. Imaging tumor angiogenesis based on these features is playing important roles in cancer diagnosis, post-therapy assessment and prognosis. Unfortunately, several challenges significantly limit current technologies. First, current clinical imaging technologies are limited in spatial resolution (i.e. how small vessels in size can be resolved, usually &...

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