|Awarded On||November 16, 2016|
|Title||Identification of novel immune targets and neoantigens for development of immunotherapy for breast cancer|
|Award Mechanism||Bridging the Gap: Early Translational Research Awards|
|Institution/Organization||The Methodist Hospital Research Institute|
|Principal Investigator/Program Director||Rongfu Wang|
Breast cancer is one of the leading causes of death in women worldwide including Texas. During 2008-2012, approximately 14000 women were diagnosed with breast cancer in Texas alone (Source: Texas Cancer Registry). Further studies are warranted to improve with stronger efficacy particularly against metastatic Triple negative breast cancer (TNBC) patients who do not respond to available standard therapy. By and large, the primary weapons in the frontline fight against breast cancer are surgical interventions, chemotherapeutic regimens or radiation therapy. The efforts in identifying immunotherapeutic approaches or regimen to treat breast cancer are emerging. However, immunotherapy now holds a...