Grant ID RP160482
Awarded On November 19, 2015
Title Nanoparticle Targeted STAT3 Immune Expression
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Amy B Heimberger
Cancer Sites Brain and Other Nervous System
Contracted Amount $888,429
Lay Summary

For the last several years there has been a great deal of enthusiasm for immunotherapeutic treatment of malignancies. This has been in large part due to recent FDA approvals of antibodies that are capable of targeting immune checkpoints (i.e. the breaks of the immune system). The key inflection point has now been reached in the field of immunology with a wide variety of robust targets, unique and innovative strategies that include and go beyond the targeting of cell surface molecules, and rigorous preclinical testing in state-of-the-art model systems. This proposal brings together unique and unprecedented expertise in immunology, neurosurgery, and translational biology, to work together to i...

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