Grant ID RP160150
Awarded On November 19, 2015
Title Radiogenomic Screen to Identify Novel Proliferation-associated Glioblastoma Genomic Therapeutic Targets: Discovery and Mechanistic Validation Study
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Rivka R Colen
Cancer Sites Brain and Other Nervous System
Contracted Amount $897,627
Lay Summary

The purpose of the research is to uncover and validate novel, relevant, and clinically meaningful genomic targets that can be subsequently developed into a therapeutic and more personalized treatment for Glioblastoma, the most common primary brain tumor. Currently, the absence of a validated method for early and cost-effective genomic target identification and selection remains a critical barrier to the development of targeted therapeutics and personalized medicine; thus, despite recent advances in novel sequencing and microarray technologies, little progress has been made and the clinical course and everyday life of a cancer patient remains largely unchanged. This study is needed to address...

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