Grant ID RP160051
Awarded On November 19, 2015
Title Improving contrast for antibody-based tumor detection using PET
Program Academic Research
Award Mechanism Individual Investigator
Institution/Organization Texas A&M University System Health Science Center
Principal Investigator/Program Director Elizabeth S Ward
Cancer Sites Bladder, Bone, Breast, Colorectal, Endocrine, Gallbladder, Head and Neck, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct, Lung and Bronchus, Lymphoma, Ovary, Pancreas, Prostate, Small Intestine, Stomach, Thyroid
Contracted Amount $887,134
Lay Summary

Non-invasive whole body imaging represents an approach for the detection and characterization of tumors without the need for surgical or biopsy procedures. Consequently, the development of new and improved imaging methods is an area of active investigation for both the identification of tumors and their monitoring during therapy. Proteins called antibodies recognize and specifically interact with target markers on tumors. These antibodies therefore have the potential to be used to detect and localize tumors using whole body imaging approaches such as positron emission tomography (PET). Due to its high sensitivity, PET is a method of choice for tumor imaging. PET involves the use of radiolabe...

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