Grant ID RP150421
Awarded On February 18, 2015
Title High-throughput Screening and Detection of Circulating Tumor Cells
Program Academic Research
Award Mechanism Individual Investigator Research Awards for Prevention and Early Detection
Institution/Organization Texas A&M Engineering Experiment Station
Principal Investigator/Program Director Victor Ugaz
Cancer Sites Breast, Prostate
Contracted Amount $1,135,450
Lay Summary

The technologies proposed here offer potential to deliver a transformative advance in cancer diagnostics and treatment by enabling rapid (~ 40 min) analysis and characterization of the entire cell population in a 1 mL blood sample. Unlike current methods based on antibody capture and fluorescent labeling, our approach eliminates the need for staining and permits all cells to be simultaneously probed, delivering at least a 10-fold reduction in analysis time, while simultaneously providing a wealth of currently unavailable morphological information across the entire cell population that can be mined to gain new diagnostically relevant insights. The goal of this proposal is to overcome remaini...

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