Grant ID | RP150408 |
Awarded On | February 18, 2015 |
Title | Cellular mechanisms of chemotherapy-induced peripheral neuropathy |
Program | Academic Research |
Award Mechanism | Individual Investigator |
Institution/Organization | The University of Texas Health Science Center at San Antonio |
Principal Investigator/Program Director | James Stockand |
Cancer Sites | All Sites |
Contracted Amount | $593,532 |
Lay Summary |
Chemotherapy-induced peripheral neuropathy (CIPN) is a clinically relevant pain syndrome observed in cancer patients undergoing chemotherapy that is a significant burden to patients and limits the dosage of anti-cancer drugs. There are no effective treatments for CIPN at this time. A more complete understanding of the causes of CIPN should allow development of analgesics for CIPN allowing for more effective anti-cancer drug treatments. The overarching goals of these studies are to understand the cause of CIPN and to develop appropriate treatment to advance the clinical utility of powerful anti-cancer drugs. These studies are relevant to improving treatment of solid tumors and other forms of ... |