|Awarded On||February 18, 2015|
|Title||Cellular mechanisms of chemotherapy-induced peripheral neuropathy|
|Award Mechanism||Individual Investigator|
|Institution/Organization||The University of Texas Health Science Center at San Antonio|
|Principal Investigator/Program Director||James Stockand|
|Cancer Sites||All Sites|
Chemotherapy-induced peripheral neuropathy (CIPN) is a clinically relevant pain syndrome observed in cancer patients undergoing chemotherapy that is a significant burden to patients and limits the dosage of anti-cancer drugs. There are no effective treatments for CIPN at this time. A more complete understanding of the causes of CIPN should allow development of analgesics for CIPN allowing for more effective anti-cancer drug treatments. The overarching goals of these studies are to understand the cause of CIPN and to develop appropriate treatment to advance the clinical utility of powerful anti-cancer drugs. These studies are relevant to improving treatment of solid tumors and other forms of ...