Grant ID PP160103
Awarded On August 17, 2016
Title Detecting Unaffected Individuals for Lynch Syndrome (DUAL): Screening, Diagnosis and NavigationNavigation
Program Prevention
Award Mechanism Evidence-Based Cancer Prevention Services - Colorectal Cancer Prevention Coalition
Institution/Organization The University of Texas Southwestern Medical Center
Principal Investigator/Program Director Nisa Kubiliun
Cancer Sites Colorectal, Corpus and Uterus, NOS, Gallbladder, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct, Ovary
Contracted Amount $2,100,000
Lay Summary

In the US there are approximately 150,000 colorectal cases per year that result in 50,000 deaths [1]. Lynch syndrome (LS), the most common hereditary colon cancer syndrome, affects approximately 1/300 individuals. Diagnosis and management of LS is a tier 1 CDC recommendation for colon cancer prevention. Remarkably, only 2% of individuals with LS have been diagnosed in the United States [2].

In the DFW area, there are approximately 12,387 individuals with LS, and about 400 of these have been identified. Underserved patients are less likely to undergo genetic testing and their access to genetic counseling services are limited [3-8]. By use of telephone and telemedicine counseling we hope ...

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