Ares Immunotherapy Inc., an early-stage biopharma company founded in 2019, is located in Cartersville, Georgia with plans to move to Houston, Texas. In this SEED application, Ares is preparing for a first -in-human clinical trial in mesothelioma, a rare and deadly cancer most frequently associated with exposure to asbestos in the past. Ares' lead candidate, called Ares meso-CAR, is a mesothelin-specific chimeric antigen receptor (CAR) T cell therapy. CAR T-cell therapy is a form of immunotherapy that uses specially altered T cells - a part of the immune system - to fight cancer. In research studies, The Ares meso-CAR has been shown to be highly effective against solid tumors in cell studie...

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Ares Immunotherapy Inc., an early-stage biopharma company founded in 2019, is located in Cartersville, Georgia with plans to move to Houston, Texas. In this SEED application, Ares is preparing for a first -in-human clinical trial in mesothelioma, a rare and deadly cancer most frequently associated with exposure to asbestos in the past. Ares' lead candidate, called Ares meso-CAR, is a mesothelin-specific chimeric antigen receptor (CAR) T cell therapy. CAR T-cell therapy is a form of immunotherapy that uses specially altered T cells - a part of the immune system - to fight cancer. In research studies, The Ares meso-CAR has been shown to be highly effective against solid tumors in cell studies and in mouse studies, where it has the ability to completely heal even large established tumors. Ares meso-CAR T also shows promise as a therapy for cancers that contain mesothelin including pancreas, lung and ovarian, as well as others. If Ares is successful in its clinical goals, it has the potential to make a major impact for patients with mesothelioma and perhaps other cancers. In moving to Texas as part of the CPRIT programs, Ares will be creating employment opportunities and expanding the Texas biotech ecosystem.

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