Grant ID DP150052
Awarded On November 19, 2014
Title High-throughput Flow-proteometric System in Screening Functional Complexes as Cancer Biomarkers
Program Academic Research
Award Mechanism Bridging the Gap: Early Translational Research Awards
Institution/Organization The University of Texas M.D. Anderson Cancer Center
Principal Investigator/Program Director Mien-Chie Hung
Cancer Sites Lung and Bronchus
Contracted Amount $1,359,649
Lay Summary

Targeted therapy is one of the most important advances in cancer treatment because it has better therapeutic efficacy and fewer side effects compared with conventional chemotherapy by targeting specific molecules responsible for cancer progression without affecting normal cellular functions. Targeted therapy is used to treat cancer from multiple aspects, such as reactivation of immune response (immuno-check point therapy) and inhibition of cancer cell proliferation, invasion, and drug resistance. Hence, accurate molecular diagnosis will be critical for doctors to prescribe an appropriate drug for patients who will most likely respond to it.

Currently, many clinical trials use “marker-guided ...

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