Jonathan Clinger is an assistant professor at Baylor University in the Department of Chemistry and Biochemistry, and his research is focused on protein structure and dynamics as they relate to function and catalysis. He has a broad background in biochemistry and biophysics, with a primary focus in structural biology and crystallography, acquired during his Ph.D. at Rice University in George Phillips's lab and his postdoctoral research at Cornell University with Robert Thorne. Dr. Clinger’s postdoctoral training focused on developing methods to capture dynamic structural data in X-ray crystallography and cryo-electron microscopy as well as making the acquisition of these data more straightforward. Lowering sample and experimental infrastructure requirements for these techniques will greatly accelerate scientific discoveries utilizing these methods. 

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Jonathan Clinger is an assistant professor at Baylor University in the Department of Chemistry and Biochemistry, and his research is focused on protein structure and dynamics as they relate to function and catalysis. He has a broad background in biochemistry and biophysics, with a primary focus in structural biology and crystallography, acquired during his Ph.D. at Rice University in George Phillips's lab and his postdoctoral research at Cornell University with Robert Thorne. Dr. Clinger’s postdoctoral training focused on developing methods to capture dynamic structural data in X-ray crystallography and cryo-electron microscopy as well as making the acquisition of these data more straightforward. Lowering sample and experimental infrastructure requirements for these techniques will greatly accelerate scientific discoveries utilizing these methods. 

In his lab at Baylor, established in 2022 with the help of a First-Time Tenure-Track Award from CPRIT, Dr. Clinger is using state-of-the-art structural biology techniques to observe intermediate states present in metabolic enzyme reactions, as well as probe the energy landscape of these enzymes experimentally. These new observations will advance the design and discovery of new inhibitors of these important biomolecules which are dysregulated in cancers and drive the uncontrolled growth associated with cancer.

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