Jeffrey B. Woodruff, Ph.D.
Jeffrey B. Woodruff, Ph.D.
The University of Texas Southwestern Medical Center
Titles & Positions

  • Assistant Professor, Department of Cell Biology and Biophysics

  • E.E. and Greer Garson Fogelson Scholar in Medical Research

Institutional & Related Links



Grant Information

Grant ID: RR170063
Grant Mechanism: 
Recruitment of First-Time, Tenure-Track Faculty Members
Recruited From: 
Max Planck Institute of Molecular Cell Biology and Genetics
Date Awarded: 
August 16, 2017
Grant Amount: 

The hallmarks of cancer are well established.  But how does a normal cell become cancerous in the first place?  It is now clear that dysregulation of a subcellular structure called the centrosome can trigger tumor formation and metastasis. My lab combines live-cell microscopy, synthetic biology, and nano-scale materials science techniques to reveal the control mechanisms that prevent centrosome dysregulation in healthy cells.

My research career began at the University of Texas at Austin, where I studied tissue development in leech embryos. During my Ph.D. at the University of California, Berkeley, I used genome analysis and live-cell microscopy to dissect the mechanisms of cell division in baker’s yeast. For my post-doc at the MPI-CBG in Dresden, Germany, I developed a molecular toolkit that allowed me to build synthetic centrosomes in a test tube.