Grant ID | CP130013 |
Awarded On | February 19, 2014 |
Title | Clinical Development and Commercialization of Oncolytic Adenovirus for Treating Malignant Glioma |
Program | Product Development Research |
Award Mechanism | Company Commercialization |
Institution/Organization | DNAtrix, Inc. |
Principal Investigator/Program Director | Frank Tufaro |
Cancer Sites | Brain and Other Nervous System |
Contracted Amount | $10,813,623 |
Lay Summary |
DNAtrix, Inc. is a Texas-based company developing modified viruses for the treatment of the most aggressive type of brain cancer called glioblastoma. Scientists have modified the common cold virus called adenovirus in 2 specific ways so that it can recognize and kill cancer cells very effectively without harming normal brain. The first product of its kind, called Delta-24-RGD, has just completed its first big test in more than 35 patients with GB at the MD Anderson Cancer Center in Houston. Many patients with GB who participated had a remarkable response to the therapy, with evidence of tumor killing and improved survival. Perhaps equally important, there were no safety concerns or side-eff... |