Glen Liszczak, Ph.D.
The University of Texas Southwestern Medical Center
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|Grant ID: RR180051|
Recruitment of First-Time, Tenure-Track Faculty Members
August 24, 2018
The tumor suppressor gene p53, known as the “guardian of the genome,” is the most commonly mutated gene in human cancers. And even when the gene itself is not mutated, disruptions in the regulatory system that controls p53 may underlie most, if not all, cancers.
While p53 itself is a hot topic of study in cancer research, less is known about this cellular regulation system. Now a biochemist at the University of Texas Southwestern Medical Center hopes to untangle these pathways in an effort to restore p53’s normal function — a potential treatment for cancer.