Funded Grants
Texas leads the nation in its commitment to the war on cancer. CPRIT has funded 1247 awards for cancer research, product development, and prevention since 2010. The total amount awarded thus far is $1,954,325,684.
Recipients of CPRIT awards include 99 academic institutions, non-profit organizations, and private companies all located in Texas. The research and prevention efforts funded by CPRIT advance the health of Texans, research superiority of the state, life science infrastructure, and the Texas economy. These projects are operating in virtually all regions of the state with Texas-based employees.
Search Instructions
There are four ways to search the grants listed below.
Simple: Enter your search term into the search box above the column you would like to filter. For example, to see grants with a title containing coalition, enter "coalition" into the search box above Title.
Or: To search for grants that contain lung or brain, enter "lung or brain" into the search box above Cancer Type.
And: To search for grants that contain both lung and brain, enter "lung and brain" into the search box above Cancer Type.
Multiple: To search for grants that are part of a coalition that focus on colorectal cancer, enter "coalition" into the search box above Title and "colorectal" into the search box above Cancer Type.
| Grant ID | Title | Program | Primary Investigator/ Program Director | Institution/ Organization | Cancer Type | Grant Award Date | Contracted Amount |
|---|---|---|---|---|---|---|---|
| DP150051 | Targeting the DC-HIL Receptor for Anti-Cancer Immunotherapy | RES | Ariizumi, Kiyoshi | The University of Texas Southwestern Medical Center | Bladder, Breast, Cervix Uteri, Colorectal, Kidney and Renal Pelvis, Lung and Bronchus, Melanoma, Pancreas, Prostate, Skin | 2014/11/19 | $1,163,655 |
| DP150052 | High-throughput Flow-proteometric System in Screening Functional Complexes as Cancer Biomarkers | RES | Hung, Mien-Chie | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2014/11/19 | $1,359,649 |
| DP150055 | Druggable Targets that Regulate the Antitumor Activity of ER-beta | RES | Li, Rong | The University of Texas Health Science Center at San Antonio | Breast | 2014/11/19 | $1,998,444 |
| DP150056 | New antibody therapy for treating leukemia | RES | Zhang, Chengcheng | The University of Texas Southwestern Medical Center | Leukemia | 2014/11/19 | $2,000,000 |
| DP150059 | Blood-based markers for screening and early detection of colorectal neoplasia | RES | Bresalier, Robert | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2014/11/19 | $1,693,599 |
| DP150061 | Preclinical Development of a Therapeutic Enzyme for Immune Checkpoint Inhibition in Cancer | RES | Georgiou, George | The University of Texas at Austin | Lung and Bronchus, Melanoma | 2014/11/19 | $1,790,486 |
| DP150064 | Novel Separase Inhibitors to Treat Refractory Breast Cancer | RES | Pati, Debananda | Baylor College of Medicine | Breast | 2014/11/19 | $2,000,000 |
| DP150065 | Development of a novel K-Ras therapeutic | RES | Hancock, John F | The University of Texas Health Science Center at Houston | Colorectal, Lung and Bronchus, Pancreas | 2014/11/19 | $1,511,840 |
| DP150069 | Oral Stat3 Inhibitor as Targeted Treatment for Triple-Negative Breast Cancer | RES | Tweardy, David J | The University of Texas M.D. Anderson Cancer Center | Breast | 2014/11/19 | $1,999,569 |
| DP150074 | Inhibitors of Hydrogen Sulfide Biosynthesis: Preclinical Development of Novel Colorectal Cancer Therapies | RES | Hellmich, Mark | The University of Texas Medical Branch at Galveston | Colorectal | 2014/11/19 | $1,605,119 |
| DP150077 | Targeting the SWI/SNF chromatin-remodeling complex in liver cirrhosis and hepatocellular carcinoma | RES | Zhu, Hao | The University of Texas Southwestern Medical Center | Gallbladder, Liver and Intrahepatic Bile Duct | 2014/11/19 | $1,357,880 |
| DP150083 | NKT Cell Platform for Cancer Immunotherapy | RES | Metelitsa, Leonid S | Baylor College of Medicine | All Sites | 2014/11/19 | $1,928,220 |
| DP150086 | Therapeutic Targeting of Skp2/Ck1 to Restore Nuclear p27 | RES | Walker, Cheryl | Texas A&M University System Health Science Center | Breast, Cervix Uteri, Kidney and Renal Pelvis, Ovary, Prostate | 2014/11/19 | $1,999,979 |
| DP150087 | Pre-IND Development of OxaliTex | RES | Sessler, Jonathan | The University of Texas at Austin | Ovary | 2014/11/19 | $1,464,504 |
| DP150091 | Selective Tumor Delivery of Anti-Cancer Agents in Ovarian Cancer Therapy | RES | Lacko, Andras | University of North Texas Health Science Center at Fort Worth | Ovary | 2014/11/19 | $742,048 |
| DP150093 | Targeting an Elusive Foe: Development of K-Ras Inhibitors | RES | Gorfe, Alemayehu | The University of Texas Health Science Center at Houston | Bladder, Colorectal, Lung and Bronchus, Pancreas, Stomach | 2014/11/19 | $1,969,826 |
| DP150094 | Genetic engineering of T cells as an “off-the-shelf” therapy for leukemias and lymphomas | RES | Cooper, Laurence | The University of Texas M.D. Anderson Cancer Center | Leukemia, Lymphoma | 2014/11/19 | $1,992,245 |
| DP150096 | ESR1 Coregulator binding site inhibitors (ECBIs) as novel therapeutics to target hormone therapy resistant metastatic breast cancer | RES | Vadlamudi, Ratna | The University of Texas Health Science Center at San Antonio | Breast, Endocrine | 2014/11/19 | $1,992,460 |
| DP150099 | Immunotherapy targeting triple negative breast cancer using NY-ESO-1-specific TCRs and blockade of immune suppression | RES | Wang, Rongfu | The Methodist Hospital Research Institute | Breast | 2014/11/19 | $1,592,992 |
| DP150102 | Image-Guided Smart Laser Knife for Cancer Surgery | RES | Milner, Thomas | The University of Texas at Austin | All Sites | 2014/11/19 | $1,694,460 |
| RP100094 | Novel angiogenic factor in ovarian cancer microenvironment | RES | Mok, Samuel C | The University of Texas M.D. Anderson Cancer Center | Ovary | 2010/01/20 | $939,821 |
| RP100107 | Understanding the Connection Between Alternative mRNA 3' End Formation and microRNA Function During Tumorigenesis | RES | Wagner, Eric J | The University of Texas Health Science Center at Houston | Basic Science, Multiple Sites | 2010/01/20 | $200,000 |
| RP100119 | A molecularly targeted anticancer therapeutic strategy premised upon attack of aberrant Wnt pathway responses | RES | Lum, Lawrence | The University of Texas Southwestern Medical Center | Multiple Sites | 2010/01/20 | $1,305,611 |
| RP100146 | Imaging cancerous tissues with liposomal MRI contrast agents that utilize bioengineered nanovalves | RES | Blount, Paul | The University of Texas Southwestern Medical Center | Multiple Sites | 2010/01/20 | $1,144,531 |
| RP100188 | Loss of Rho GDI alpha enhances metastasis and resistance to tamoxifen | RES | Fuqua, Suzanne A | Baylor College of Medicine | Breast | 2010/01/20 | $814,544 |
| RP100189 | Systemic Cancer Immunotherapy Using Gold Nanoparticle Loaded Tumor-Specific Cytotoxic T Lymphocytes | RES | Drezek, Rebekah A | Rice University | Multiple Sites | 2010/01/20 | $200,000 |
| RP100202 | Analysis of histone code alterations and the role of histone demethylase JMJD3 using CHIP-seq in myelodysplastic syndrome | RES | Garcia-Manero, Guillermo | The University of Texas M.D. Anderson Cancer Center | Leukemia, Myelodysplastic Syndrome | 2010/01/20 | $777,451 |
| RP100233 | Comprehensive Analysis of Genetic and Epigenetic Changes in Oral Cancer | RES | Myers, Jeffrey | The University of Texas M.D. Anderson Cancer Center | Head and Neck, Oral Cavity and Pharynx | 2010/06/18 | $2,528,196 |
| RP100320 | A Novel Approach to Selectively Inhibit Androgen Receptor Action to Treat Prostate Cancer | RES | Weigel, Nancy L | Baylor College of Medicine | Prostate | 2010/01/20 | $947,367 |
| RP100329 | Next Generation Genomic Sequence Identification of the 19q Familial Wilms Tumor Predisposition Gene | RES | Huff, Vicki | The University of Texas M.D. Anderson Cancer Center | Childhood and Adolescent, Kidney and Renal Pelvis, Wilms' Tumor | 2010/01/20 | $558,951 |
| RP100348 | Development of small molecule inhibitors that target the oncogenic SRC-3 coactivator and their characterization as novel anti-cancer agents | RES | O'Malley, Bert | Baylor College of Medicine | Breast, Colorectal, Lung and Bronchus, Multiple Sites, Ovary, Pancreas, Prostate | 2010/01/20 | $789,473 |
| RP100400 | Adipose progenitor cells as a new clinical cancer target | RES | Kolonin, Mikhail G | The University of Texas Health Science Center at Houston | Multiple Sites | 2010/01/20 | $200,000 |
| RP100402 | The role of IGFBP2 in acute myeloid leukemia | RES | Zhang, Chengcheng | The University of Texas Southwestern Medical Center | Leukemia | 2010/01/20 | $1,221,879 |
| RP100406 | Investigation of Highly Potent Benzosuberene Analogs as Novel Anticancer Agents | RES | Pinney, Kevin G | Baylor University | Multiple Sites | 2010/01/20 | $200,000 |
| RP100421 | Chemical Probes for Signal Transducer and Activator of Transcription (STAT) 3 that Selectively Target Leukemia-Initiating Cells | RES | Tweardy, David J | Baylor College of Medicine | Leukemia | 2010/01/20 | $1,105,262 |
| RP100429 | Regulation of Ash2L and MLL oncoproteins by PRMT-mediated methylation in normal cells and acute leukemias | RES | Dent, Sharon | The University of Texas M.D. Anderson Cancer Center | Childhood and Adolescent, Leukemia | 2010/01/20 | $949,549 |
| RP100430 | Cord Blood Natural Killer Cells for Patients with Cancer | RES | Shpall, Elizabeth | The University of Texas M.D. Anderson Cancer Center | Leukemia, Lymphoma, Multiple Sites, Myeloma | 2010/01/20 | $200,000 |
| RP100437 | Can glioblastoma growth be suppressed by targeting glutamine metabolism? | RES | DeBerardinis, Ralph J | The University of Texas Southwestern Medical Center | Brain and Other Nervous System, Glioblastoma | 2010/01/20 | $200,000 |
| RP100443 | Effects from Nicotinic Receptor Variations on Smoking Behaviors and Lung Cancer Risk | RES | Krahe, Ralf | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2010/01/20 | $1,441,152 |
| RP100456 | Photonic Probes for Functional Anaylsis of microRNAs and mRNAs in Living Cells | RES | Li, Wen-hong | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $755,754 |
| RP100457 | Translational development of novel lymphoma vaccine therapy | RES | Kwak, Larry | The University of Texas M.D. Anderson Cancer Center | Lymphoma | 2010/01/20 | $842,104 |
| RP100469 | Improving Cord Blood Expansion and Homing for Patients with Cancer | RES | Shpall, Elizabeth | The University of Texas M.D. Anderson Cancer Center | Multiple Sites | 2010/06/18 | $2,849,974 |
| RP100473 | Identification of selective modifiers of crypt stem cells the cells of origin of intestinal cancer | RES | Chapkin, Robert S | Texas Agrilife Research | Colorectal | 2010/01/20 | $199,894 |
| RP100475 | Evaluation of the utility of two-dimensional RNA biomarker analysis in classification of human cancers. | RES | Neilson, Joel R | Baylor College of Medicine | Basic Science, Multiple Sites | 2010/01/20 | $200,000 |
| RP100483 | K-ras Spatiotemporal Dynamics: Novel Therapeutic Targets | RES | Hancock, John F | The University of Texas Health Science Center at Houston | Basic Science, Colon, Lung and Bronchus, Multiple Sites, Pancreas | 2010/01/20 | $1,451,875 |
| RP100484 | Human T lymphocytes with anti-viral and anti-leukemic specificity as protection against infection and relapse after stem cell and cord blood transplantation | RES | Bollard, Catherine M | Baylor College of Medicine | Childhood and Adolescent, Leukemia | 2010/01/20 | $1,128,885 |
| RP100502 | The Role of Net1 in the Cellular Response to Ionizing Radiation in Breast Cancer | RES | Frost, Jeffrey | The University of Texas Health Science Center at Houston | Breast | 2010/06/18 | $1,093,462 |
| RP100516 | An Improved Transgenesis Platform for Systematic Screening of Tumor Suppressor Activity in Complete Gene Families in Drosophila | RES | Buszczak, Michael | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/06/18 | $721,209 |
| RP100528 | Targeting Tumor Microenvironment by NKT Cells | RES | Metelitsa, Leonid S | Baylor College of Medicine | Multiple Sites | 2010/01/20 | $947,367 |
| RP100535 | A single nucleotide polymorphism in Mdm2 regulates p53 activity | RES | Lozano, Guillermina | The University of Texas M.D. Anderson Cancer Center | Basic Science, Breast, Multiple Sites | 2010/01/20 | $813,681 |
| RP100550 | Model Systems and Translational Studies of Cervical Cancer Progression | RES | Castrillon, Diego H | The University of Texas Southwestern Medical Center | Cervix Uteri | 2010/01/20 | $818,731 |
| RP100561 | Dissecting the Hippo tumor suppressor pathway in organ size control and stem cell proliferation | RES | Jiang, Jin | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $1,130,243 |
| RP100602 | TRIM24: a Dual Regulator of p53 and Estrogen Receptor | RES | Barton, Michelle | The University of Texas M.D. Anderson Cancer Center | Breast | 2010/06/18 | $1,460,523 |
| RP100612 | Molecular Engineering and Preclinical Evaluation of High Potency Therapeutic Antibodies for the Treatment of Cancer | RES | Georgiou, George | The University of Texas at Austin | Multiple Sites | 2010/01/20 | $200,000 |
| RP100625 | TAMU-UT Southwestern Partnership for Cancer Imaging and Spectroscopy at 7 Tesla | RES | Malloy, Craig | The University of Texas Southwestern Medical Center | Basic Science, Brain and Other Nervous System, Breast, Multiple Sites | 2010/01/20 | $1,173,255 |
| RP100627 | A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy | RES | Wong, Stephen | The Methodist Hospital Research Institute | Lung and Bronchus | 2010/01/20 | $1,155,019 |
| RP100644 | Impact of GBM-Specific Oncogenic Events on DNA Repair Pathways: Implications for Therapy | RES | Burma, Sandeep | The University of Texas Southwestern Medical Center | Brain and Other Nervous System, Glioblastoma | 2010/01/20 | $857,106 |
| RP100670 | ATM Activation by Oxidative Stress: Characterization and Regulation of Signal Transduction Induced by Reactive Oxygen species | RES | Paull, Tanya | The University of Texas at Austin | Basic Science | 2010/06/18 | $527,974 |
| RP100674 | Small-molecule differentiation agent to target glioma stem cells | RES | Hsieh, Jenny | The University of Texas Southwestern Medical Center | Brain and Other Nervous System, Glioblastoma | 2010/01/20 | $587,042 |
| RP100678 | Discovery of Novel Anti-Tumor Therapeutics Targeted at Colon Cancer Stem Cells | RES | Liu, Qingyun | The University of Texas Health Science Center at Houston | Colorectal | 2010/01/20 | $1,280,107 |
| RP100680 | Ligand-Dependent Stabilization and Rescue of a Compromised Tumor Suppressor | RES | Webb, Paul | The Methodist Hospital Research Institute | Brain and Other Nervous System, Breast | 2010/06/18 | $199,725 |
| RP100686 | New treatments for mutant K-Ras: the elephant in the room of cancer therapy. | RES | Powis, Garth | The University of Texas M.D. Anderson Cancer Center | Basic Science, Multiple Sites | 2010/01/20 | $200,000 |
| RP100695 | Self-Antigen Dependence of Chronic Active B-Cell Receptor Signaling in the Activated B-Cell Type of Diffuse Large B-Cell Lymphoma | RES | Davis, Richard E | The University of Texas M.D. Anderson Cancer Center | Lymphoma | 2010/01/20 | $971,675 |
| RP100708 | Development of a novel anti-EGFR antibody-protamine recombinant protein for in vivo delivery of small interfering RNAs for cancer therapy | RES | Fan, Zhen | The University of Texas M.D. Anderson Cancer Center | Multiple Sites | 2010/01/20 | $200,000 |
| RP100718 | Development of small molecules mimicking pro-apoptotic proteins for treating prostate cancer | RES | Ahn, Jung-Mo | The University of Texas at Dallas | Prostate | 2010/01/20 | $886,693 |
| RP100726 | 14-3-3zeta-induced microRNA deregulation in early stage breast cancer progression | RES | Yu, Dihua | The University of Texas M.D. Anderson Cancer Center | Breast | 2010/01/20 | $784,241 |
| RP100728 | Development of a Synergistic Genetically Enhanced Dendritic Cell/Natural Killer T Cell Vaccine for Cancer | RES | Levitt, Jonathan | Baylor College of Medicine | Multiple Sites | 2010/06/18 | $939,760 |
| RP100735 | Bioengineering Cancer Immunotherapy: A Synthetic Injectable Microenvironment for DC Migration, Activation and Antigen priming | RES | Roy, Krishnendu | The University of Texas at Austin | Lymphoma, Multiple Sites | 2010/01/20 | $1,094,486 |
| RP100756 | Integrated Microfluidic Technology for High Throughput Screening of the Metastatic Potential of Tumor Cells | RES | Vanapalli, Siva | Texas Tech University | Basic Science, Multiple Sites | 2010/06/18 | $199,796 |
| RP100762 | Enhancing the Anti-Neuroblastoma Activity of Fenretinide by Identifying and Targeting Sphingolipid Pathways that Confer Resistance | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | Brain and Other Nervous System, Childhood and Adolescent, Lymphoma, Neuroblastoma | 2010/06/18 | $1,220,556 |
| RP100768 | Mechanisms underlying delayed recurrence of ER positive breast cancer: a critical step in the development of effective biomarkers and therapies | RES | Mills, Gordon B | The University of Texas M.D. Anderson Cancer Center | Breast | 2010/01/20 | $978,679 |
| RP100773 | Discovery and Validation of Novel Cancer Drug Targets through Synthetic Lethal Screening | RES | Mills, Gordon B | The University of Texas M.D. Anderson Cancer Center | Basic Science, Multiple Sites | 2010/01/20 | $963,854 |
| RP100777 | Suppressing maturation of an oncogenic microRNA with small molecules. | RES | Luebke, Kevin J | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $900,212 |
| RP100781 | Novel Therapy for Lung Cancers Using Adult Stem/Progenitor Cells | RES | Prockop, Darwin J | Texas A&M University System Health Science Center Research Foundation | Lung and Bronchus | 2010/01/20 | $947,367 |
| RP100782 | Genetic mouse models of glioma: translational tools for therapeutic development | RES | Parada, Luis F | The University of Texas Southwestern Medical Center | Brain and Other Nervous System, Glioblastoma | 2010/01/20 | $1,149,584 |
| RP100805 | Selective Mitochondrial Autophagy in the Protection Against Cancer | RES | Wang, Jin | Baylor College of Medicine | Basic Science, Multiple Sites | 2010/01/20 | $871,940 |
| RP100841 | Osteoclast Regulation of Bone Metastasis of Cancer | RES | Wan, Yihong | The University of Texas Southwestern Medical Center | Bone Metastases, Breast, Prostate | 2010/01/20 | $947,367 |
| RP100846 | Discovery and optimization of natural and artificial ligands regulating Hypoxia Inducible Factor | RES | Gardner, Kevin | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $1,555,050 |
| RP100861 | A new phamacoviral approach to treat Malignant Gliomas | RES | Costa-Mattioli, Mauro | Baylor College of Medicine | Brain and Other Nervous System, Glioblastoma | 2010/01/20 | $1,000,161 |
| RP100865 | Cancer Communication Interventions to Increase HPV Vaccination among Hispanic Adolescents | RES | Fernandez, Maria E | The University of Texas Health Science Center at Houston | Cervix Uteri, Childhood and Adolescent | 2010/01/20 | $1,448,244 |
| RP100890 | Advanced (Pre-IND) Preclinical Development of a Novel, Highly Promising, Human Therapeutic Protein For the Treatment of Hepatocellular Carcinoma | RES | Georgiou, George | The University of Texas at Austin | Liver and Intrahepatic Bile Duct | 2010/01/20 | $2,025,246 |
| RP100900 | Relating drug resistance and tumor microenvironment to cancer cell heterogeneity | RES | Wu, Lani F | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $1,490,711 |
| RP100932 | Multi-Modal Optical Imaging Systems for Early Detection of Oral Cancer | RES | Richards-Kortum, Rebecca R | Rice University | Head and Neck, Oral Cavity and Pharynx | 2010/01/20 | $1,834,699 |
| RP100934 | Antibody-free microfluidic isolation and molecular analysis of circulating cancer cells | RES | Gascoyne, Peter R | The University of Texas M.D. Anderson Cancer Center | Breast, Multiple Sites, Ovary | 2010/01/20 | $913,709 |
| RP100941 | Mapping Inhibitor Interactions and Conformational Space of the MAP3K TAO2, a New Protein Kinase Cancer Drug Target | RES | Goldsmith, Elizabeth J | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/01/20 | $682,622 |
| RP100960 | Prostaglandins and Inflammation in Colorectal Cancer | RES | DuBois, Raymond | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2010/01/20 | $1,198,243 |
| RP100976 | Evaluating the therapeutic potential of a potent anti-cancer agent | RES | Ready, Joseph M | The University of Texas Southwestern Medical Center | Breast, Colon, Multiple Sites | 2010/01/20 | $737,315 |
| RP101016 | Understanding the Activity of a Potent Anticancer Agent | RES | Ready, Joseph M | The University of Texas Southwestern Medical Center | Multiple Sites | 2010/01/20 | $198,947 |
| RP101017 | Genetics of Osteosarcoma | RES | Lee, Brendan | Baylor College of Medicine | Childhood and Adolescent, Osteosarcoma, Sarcoma | 2010/01/20 | $789,473 |
| RP101042 | Validation of a MCL1 Promoter Deletion as a Molecular Marker for Sensitivity to Bcl-2 Inhibitors in Pediatric Acute Lymphoblastic Leukemia | RES | Kang, Min H | Texas Tech University Health Sciences Center | Childhood and Adolescent, Leukemia | 2010/01/20 | $601,729 |
| RP101073 | Molecular mechanisms of novel inhibitors of the multidrug resistance P-glycoprotein | RES | Altenberg, Guillermo A | Texas Tech University Health Sciences Center | Basic Science, Multiple Sites | 2010/01/20 | $742,572 |
| RP101075 | Identification of a Novel Oncogene in Clear-Cell Renal Cell Carcinoma | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2010/06/18 | $1,202,854 |
| RP101089 | Whole Genome Approaches to Define the Inherited Basis of Childhood Cancer | RES | Plon, Sharon E | Baylor College of Medicine | Childhood and Adolescent, Multiple Sites | 2010/01/20 | $2,023,533 |
| RP101120 | Creation of Animal Models and Characterization of Nicotinic Receptor Cancer Risk Factors | RES | Dani, John A | Baylor College of Medicine | Lung and Bronchus | 2010/01/20 | $741,765 |
| RP101195-C1 | Administrative and Clinical Data Core [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Tomlinson, G. E. | The University of Texas Health Science Center at San Antonio | 2010/06/18 | $278,495 | |
| RP101195-C2 | Pathology Core [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Finegold, Milton | Baylor College of Medicine | 2010/06/18 | $84,774 | |
| RP101195-C3 | Core 3 | RES | Rakheja, Dinesh | The University of Texas Southwestern Medical Center | 2010/06/18 | $181,967 | |
| RP101195-C4 | Bioinformatics and Biostatistics Core [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Chen, Yidong | The University of Texas Health Science Center at San Antonio | 2010/06/18 | $776,608 | |
| RP101195-P1 | Expression and microRNA profiling of hepatoblastoma [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Lopez-Terrada, Dolores | Baylor College of Medicine | 2010/06/18 | $214,458 | |
| RP101195-P2 | Genomic characterization of hepatoblastoma using massively-parallel DNA sequencing [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Parsons, Donald | Baylor College of Medicine | 2010/06/18 | $703,046 | |
| RP101195-P3 | Development of a Mouse Model of Hepatoblastoma [Genetics and Biology of Liver Tumorigenesis in Children] | RES | Commerford, Sarah | The University of Texas Southwestern Medical Center | 2010/06/18 | $70,000 | |
| RP101207-C1 | Data Management Core [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Cooksley, Catherine | The University of Texas Medical Branch at Galveston | 2010/06/18 | $827,528 | |
| RP101207-C2 | Training Core [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Freeman, Jean | The University of Texas Medical Branch at Galveston | 2010/06/18 | $741,183 | |
| RP101207-C3 | Knowledge Transition Core [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Eschbach, Karl | The University of Texas Medical Branch at Galveston | 2010/06/18 | $274,491 | |
| RP101207-C4 | Administrative Core [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | 2010/06/18 | $309,865 | |
| RP101207-P1 | Evaluation of Cancer Screening Practices [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | 2010/06/18 | $508,517 | |
| RP101207-P2 | Assessing the Quality of Cancer Treatment in Texas [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Giordano, Sharon | The University of Texas M.D. Anderson Cancer Center | 2010/06/18 | $872,325 | |
| RP101207-P3 | Quality of Post Treatment Surveillance for Cancer Patients in Texas [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Riall, Taylor | The University of Texas Medical Branch at Galveston | 2010/06/18 | $554,487 | |
| RP101207-P4 | Quality of Supportive Care of Texans with Cancer [CERCIT: Comparative Effectiveness Research on Cancer in Texas] | RES | Elting, Linda | The University of Texas M.D. Anderson Cancer Center | 2010/06/18 | $772,779 | |
| RP101215 | Biomarker Profiles of Cancer Pain Phenotypes | RES | Gutstein, Howard | The University of Texas M.D. Anderson Cancer Center | Other | 2010/01/20 | $25,000 |
| RP101218 | CTNet: Clinical Trial Network | RES | Geyer, Charles | Statewide Clinical Trials Network of Texas (CTNet) | 2010/06/18 | $25,213,675 | |
| RP101230 | Lonestar Oncology Network for EpigeneticS Therapy And Research | RES | Dent, Sharon | The University of Texas M.D. Anderson Cancer Center | Other | 2010/01/20 | $22,600 |
| RP101243-C1 | Hyperpolarized 13C tracers of cancer metabolism [Novel MRI and MRS Methods for Imaging Cancer Metabolism] | RES | Sherry, Dean | The University of Texas Southwestern Medical Center | 2010/06/18 | $92,666 | |
| RP101243-P2 | Biomarkers and Metabolic Pathways in Gliomas [Novel MRI and MRS Methods for Imaging Cancer Metabolism] | RES | Bachoo, Robert | The University of Texas Southwestern Medical Center | 2010/06/18 | $640,609 | |
| RP101243-P3 | Metabolic Imaging of Hyperpolarized 13C Substrates in Animal Models of Cancer [Novel MRI and MRS Methods for Imaging Cancer Metabolism] | RES | Merritt, Matthew | The University of Texas Southwestern Medical Center | 2010/06/18 | $638,147 | |
| RP101243-P4 | High field MRS and CEST imaging of brain tumors: Biomarkers of therapeutic response [Novel MRI and MRS Methods for Imaging Cancer Metabolism] | RES | Choi, Changho | The University of Texas Southwestern Medical Center | 2010/06/18 | $792,841 | |
| RP101243-P5 | Fast Imaging Methods for Hyperpolarized Nuclei [Novel MRI and MRS Methods for Imaging Cancer Metabolism] | RES | Bankson, James | The University of Texas M.D. Anderson Cancer Center | 2010/06/18 | $474,644 | |
| RP101251-P1 | Development of nuclear receptor and coregulator profiles for diagnostic and therapeutic (theragnostic) targeting of breast and lung cancers | RES | Mangelsdorf, David | The University of Texas Southwestern Medical Center | 2010/06/18 | $108,292 | |
| RP101251-P2 | Project 2 | RES | O'Malley, Bert | Baylor College of Medicine | 2010/06/18 | $856,962 | |
| RP101251-P3 | Project 3 | RES | Wistuba, Ignacio | The University of Texas M.D. Anderson Cancer Center | 2010/06/18 | $273,684 | |
| RP101251-P4 | Project 4 | RES | Xu, Jianming | Baylor College of Medicine | 2010/06/18 | $609,998 | |
| RP101251-P5 | Project 5 | RES | Minna, John | The University of Texas Southwestern Medical Center | 2010/06/18 | $1,618,023 | |
| RP101251-P6 | Project 6 | RES | Kittler, Ralf | The University of Texas Southwestern Medical Center | 2010/06/18 | $500,000 | |
| RP101251-P7 | Project 7 | RES | Fuqua, Suzanne A | Baylor College of Medicine | 2010/06/18 | $608,990 | |
| RP101255 | Cancer in the Era of Obesity | RES | Bickel, Perry | The University of Texas Health Science Center at Houston | Other | 2010/01/20 | $12,000 |
| RP101280 | DNA Double-Strand Break Repair and Genome Stability | RES | Chen, David | The University of Texas Southwestern Medical Center | Other | 2010/01/20 | $25,000 |
| RP101335-C1 | Administrative and Biostatistical Core [Targeted Therapies for Metastatic Osteosarcoma] | RES | Poplack, David | Baylor College of Medicine | 2010/06/18 | $260,659 | |
| RP101335-C2 | Preclinical Functional Core [Targeted Therapies for Metastatic Osteosarcoma] | RES | Yustein, Jason | Baylor College of Medicine | 2010/06/18 | $350,265 | |
| RP101335-C3 | Genomics Core [Targeted Therapies for Metastatic Osteosarcoma] | RES | Rao, Pulivarthi | Baylor College of Medicine | 2010/06/18 | $317,547 | |
| RP101335-C4 | Histopathology Core [Targeted Therapies for Metastatic Osteosarcoma] | RES | Hicks, John | Baylor College of Medicine | 2010/06/18 | $277,968 | |
| RP101335-P1 | Utilization of Novel Mouse Models to Provide Insights into Molecular Mechanisms of Metastatic Osteosarcoma [Targeted Therapies for Metastatic Osteosarcoma] | RES | Donehower, Lawrence | Baylor College of Medicine | 2010/06/18 | $620,168 | |
| RP101335-P2 | Genomic and Proteomic Approaches for Predicting Metastasis in Osteosarcoma [Targeted Therapies for Metastatic Osteosarcoma] | RES | Lau, Ching | Baylor College of Medicine | 2010/06/18 | $932,059 | |
| RP101335-P3 | Targeting Metastatic Osteosarcoma with Antigen-specific T cells [Targeted Therapies for Metastatic Osteosarcoma] | RES | Gottschalk, Stephen | Baylor College of Medicine | 2010/06/18 | $815,468 | |
| RP101353-P1 | Operational Goals Steering Oversight and Management [Tumor Banking For Genomic Research And Clinical Translation] | RES | Gibbs, Richard | Baylor College of Medicine | 2010/06/18 | $757,570.71 | |
| RP101353-P11 | Project 11 | RES | Gibbs, Richard | Baylor College of Medicine | 2010/06/18 | $73,694.64 | |
| RP101353-P12 | Project 12 | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | 2010/06/18 | $527,823 | |
| RP101353-P2 | Project 2 | RES | Ayala, Gustavo | Baylor College of Medicine | 2010/06/18 | $919,068.05 | |
| RP101353-P3 | Project 3 | RES | Ayala, Gustavo | Baylor College of Medicine | 2010/06/18 | $684,232.07 | |
| RP101353-P4 | ELSI and Public Policy [Tumor Banking For Genomic Research And Clinical Translation] | RES | McGuire, Amy | Baylor College of Medicine | 2010/06/18 | $407,242.42 | |
| RP101353-P5 | Project 5 | RES | Gibbs, Richard | Baylor College of Medicine | 2010/06/18 | $1,734,521.57 | |
| RP101353-P6 | Project 6 | RES | Becnel, Lauren | Baylor College of Medicine | 2010/06/18 | $473,123.91 | |
| RP101353-P7 | Sample Sites [Tumor Banking For Genomic Research And Clinical Translation] | RES | Fisher, William | Baylor College of Medicine | 2010/06/18 | $729,487.88 | |
| RP101353-P8 | Project 8 | RES | Nemunaitis, John | Gradalis, Inc. | 2010/06/18 | $806,790.75 | |
| RP101353-P9 | Project 9 | RES | Ullrich, Robert | The University of Texas Medical Branch at Galveston | 2010/06/18 | $77,950.86 | |
| RP101362 | Applying genomics and other high throughput technologies to the prevention and treatment of colon cancer | RES | Shay, Jerry W | The University of Texas Southwestern Medical Center | Other | 2010/01/20 | $17,000 |
| RP101374 | Mechanism of posttransplant thrombotic microangiopathy | RES | Afshar-Kharghan, Vahid | The University of Texas M.D. Anderson Cancer Center | Other | 2010/01/20 | $15,000 |
| RP101380 | Texas Cancer Clinical Trial Listing and Matching Service: A module of the CTNet Project Collaboration | RES | Weinberg, Armin | Texas Life Science Foundation | Other | 2010/01/20 | $7,745 |
| RP101382-C1 | Core 1 | RES | Vigneswaran, Nadarajah | The University of Texas Health Science Center at Houston | 2010/06/18 | $590,260 | |
| RP101382-C2 | Core 2 | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | 2010/06/18 | $747,757 | |
| RP101382-C3 | Core 3 | RES | Redding, Spencer | The University of Texas Health Science Center at San Antonio | 2010/06/18 | $617,890 | |
| RP101382-P1 | Texas Cancer Diagnostics Pipeline Consortium | RES | McDevitt, John | Rice University | 2010/06/18 | $3,215,077 | |
| RP101382-P2 | Project 2 | RES | Thompson, Ian M | The University of Texas Health Science Center at San Antonio | 2010/06/18 | $863,999 | |
| RP101399 | Planning Award to Develop Research Strategy for Predictive Biomarker Assays for Prostate Cancer in Different Ethnic Populations | RES | Roby, Rhonda | University of North Texas Health Science Center at Fort Worth | Other | 2010/01/20 | $9,500 |
| RP101489 | Research Training Award | RES | Bose, Rathindra | University of Houston | Multiple Sites | 2010/06/18 | $2,387,664 |
| RP101491 | Research Training Award | RES | Oyajobi, Babatunde | The University of Texas Health Science Center at San Antonio | Multiple Sites | 2010/06/18 | $2,389,107 |
| RP101496 | Research Training Award | RES | White, Michael | The University of Texas Southwestern Medical Center | Multiple Sites | 2010/06/18 | $2,881,578 |
| RP101499 | Research Training Award | RES | Rosen, Jeffrey M | Baylor College of Medicine | Multiple Sites | 2010/06/18 | $2,361,945 |
| RP101501 | Research Training Award | RES | Sessler, Jonathan | The University of Texas at Austin | Multiple Sites | 2010/06/18 | $2,486,841 |
| RP101502 | Research Training Award | RES | Watowich, Stephanie | The University of Texas M.D. Anderson Cancer Center | Multiple Sites | 2010/06/18 | $2,565,789 |
| RP101503 | Research Training Award | RES | Ness, Roberta | The University of Texas Health Science Center at Houston | Multiple Sites | 2010/06/18 | $2,617,614 |
| RP110005 | The miR-200 family and metastatic prostate cancer | RES | Xin, Li | Baylor College of Medicine | Prostate | 2010/10/29 | $524,044 |
| RP110025 | Pathways Linking Social Determinants of Smoking Cessation | RES | Wetter, David W | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2010/10/29 | $1,226,680 |
| RP110028 | Role of DNA Methylgransferase 3B in normal and malignant hematopoiesis | RES | Goodell, Margaret A | Baylor College of Medicine | Leukemia | 2010/10/29 | $1,486,780 |
| RP110040 | Inhibition of the Wip1 oncogenic phosphatase as an anti-cancer strategy | RES | Donehower, Lawrence A | Baylor College of Medicine | Breast, Multiple Sites | 2010/10/29 | $1,016,690 |
| RP110041 | Unraveling the Molecular Mechanisms and Biomechanics of Glioblastoma Invasion | RES | Bachoo, Robert | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2010/10/29 | $941,314 |
| RP110050 | Novel Epigenetic Modulators Targeting Leukemia Initiating Cells | RES | Song, Yongcheng | Baylor College of Medicine | Childhood and Adolescent, Leukemia | 2010/10/29 | $1,149,256 |
| RP110054 | Genetic Analysis of Anticipation in Lynch Syndrome | RES | Frazier, Marsha L | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2010/10/29 | $1,481,309 |
| RP110069 | Subcellular trafficking studies of Her2 and anti-Her2 antibodies | RES | Ober, Raimund J | The University of Texas at Dallas | Basic Science, Multiple Sites | 2010/10/29 | $1,027,278 |
| RP110070 | Targeting HER2 for cancer therapy | RES | Ward, Elizabeth S | The University of Texas Southwestern Medical Center | Basic Science, Breast, Multiple Sites | 2010/10/29 | $1,209,248 |
| RP110075 | Mechanical Force-Induced Signaling for Local Estrogen Production in Breast Cancer | RES | Li, Rong | The University of Texas Health Science Center at San Antonio | Breast | 2010/10/29 | $499,998 |
| RP110076 | Deconstructing oncogenic activity of p53 mutations | RES | Abrams, John M | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/10/29 | $787,496 |
| RP110080 | Role of ST6GALNAC5's sialoside products in breast cancer metastasis to the brain | RES | Kohler, Jennifer J | The University of Texas Southwestern Medical Center | Breast | 2010/10/29 | $519,942 |
| RP110090 | Inhibiting miR-451 as a novel treatment modality for polycythemia, a pre-leukemic disease | RES | Huang, Lily J | The University of Texas Southwestern Medical Center | Leukemia | 2010/10/29 | $200,000 |
| RP110098 | Determining the Functional Role of microRNAs in Viral Tumorigenesis. | RES | Sullivan, Christopher S | The University of Texas at Austin | Basic Science, Multiple Sites | 2010/10/29 | $595,371 |
| RP110107 | A therapeutic approach for lung cancer chemoprevention | RES | Wu, Xiangwei | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2010/10/29 | $1,010,066 |
| RP110129 | Genetic Engineering of Universal NKT Cells for Cancer Immunotherapy | RES | Metelitsa, Leonid S | Baylor College of Medicine | Multiple Sites | 2010/10/29 | $200,000 |
| RP110132 | Posttranscriptional regulation of noncoding RNAs involved in epigenetic regulation of gene expression | RES | Conrad, Nicholas K | The University of Texas Southwestern Medical Center | Basic Science, Breast, Multiple Sites | 2010/10/29 | $300,000 |
| RP110153 | The role of Tcf3 in skin squamous cell carcinoma | RES | Nguyen, Hoang | Baylor College of Medicine | Skin | 2010/10/29 | $938,203 |
| RP110165 | Protein scaffolds for targeted delivery of toxic iron to cancer cells | RES | Kurtz, Donald | The University of Texas at San Antonio | Basic Science, Multiple Sites | 2010/10/29 | $199,906 |
| RP110166 | Mast Cell Tryptases in Lung Cancer Development and Progression | RES | Adachi, Roberto | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2010/10/29 | $919,462 |
| RP110172 | Chemo-immunotherapy for Relapsed or Refractory Nasopharyngeal Carcinoma | RES | Louis, Chrystal U | Baylor College of Medicine | Head and Neck, Oral Cavity and Pharynx | 2010/10/29 | $1,241,680 |
| RP110178 | Identification of the MicroRNAs-TRAF6 pathway as a therapeutic target for prostate cancer | RES | Lin, Hui-Kuan | The University of Texas M.D. Anderson Cancer Center | Basic Science, Multiple Sites, Prostate | 2010/10/29 | $631,578 |
| RP110183 | Role of the Histone Demethylase UTX in Breast Cancer Events | RES | Lee, Min Gyu | The University of Texas M.D. Anderson Cancer Center | Breast | 2010/10/29 | $789,471 |
| RP110187 | Neuroblastoma-Derived Secretory Protein Receptor, a New Target for Neuroblastoma Therapy | RES | Nuchtern, Jed G | Baylor College of Medicine | Brain and Other Nervous System, Childhood and Adolescent | 2010/10/29 | $335,398 |
| RP110189 | Discovery of Small Molecule Activators of NR4A Orphan Nuclear Receptors for Treatment of Acute myeloid Leukemia. | RES | Conneely, Orla M | Baylor College of Medicine | Leukemia | 2010/10/29 | $500,000 |
| RP110200 | Rational combinatorial targeting of PDE4 and associated survival pathways in B-cell malignancies | RES | Aguiar, Ricardo | The University of Texas Health Science Center at San Antonio | Lymphoma | 2010/10/29 | $797,800 |
| RP110202 | Role of TMEM127 in the endomembrane system and mTOR signaling | RES | Dahia, Patricia L | The University of Texas Health Science Center at San Antonio | Neuroendocrine | 2010/10/29 | $919,898 |
| RP110223 | A novel strategy for attacking tumors based on the identification of a fundamental carbon-source signal driving cell growth | RES | Tu, Benjamin P | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/10/29 | $200,000 |
| RP110248 | Augmenting T cell-based melanoma immunotherapy by targeting oncogenic BRAF | RES | Hwu, Patrick | The University of Texas M.D. Anderson Cancer Center | Melanoma | 2010/10/29 | $1,077,522 |
| RP110252 | Deciphering the mechanisms of EGFR-regulated Warburg effect during tumorigenesis | RES | Lu, Zhimin | The University of Texas M.D. Anderson Cancer Center | Basic Science, Breast, Multiple Sites | 2010/10/29 | $864,120 |
| RP110262 | Rationally designed magnetic nanoconstructs for the imaging and hyperthermia of tumor cells and neovasculature | RES | Decuzzi, Paolo | The Methodist Hospital Research Institute | Brain and Other Nervous System | 2010/10/29 | $1,499,996 |
| RP110291 | Targeting Oncoprotein Folding Intermediates to Treat Cancer | RES | Tweardy, David J | Baylor College of Medicine | Basic Science, Multiple Sites | 2010/10/29 | $200,000 |
| RP110299 | Cellular Targets of Salinomycin: Novel Cancer Stem-Cell Specific Drug Studied in Yeast | RES | Siede, Wolfram | University of North Texas Health Science Center at Fort Worth | Basic Science, Multiple Sites | 2010/10/29 | $170,334 |
| RP110319 | Targeting Dendritic Cells to Block Immunosuppression in Breast Cancer | RES | Liu, Yong-Jun | Baylor Research Institute | Breast | 2010/10/29 | $1,137,984 |
| RP110322 | Targeting Leukemia-Stromal Interaction to Overcome Drug Resistance in vivo: Novel mechanism and Development of a New Therapeutic Agent | RES | Huang, Peng | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2010/10/29 | $595,364 |
| RP110324 | Impact of differentiation status on tumorigenesis | RES | Huff, Vicki | The University of Texas M.D. Anderson Cancer Center | Basic Science, Childhood and Adolescent, Kidney and Renal Pelvis, Multiple Sites | 2010/10/29 | $1,147,268 |
| RP110327 | Prostate Cancer Bone Metastasis Secretome | RES | Lin, Sue-Hwa | The University of Texas M.D. Anderson Cancer Center | Prostate | 2010/10/29 | $614,952 |
| RP110329 | Personalized Online Adaptive Radiation Therapy | RES | Mao, Weihua | The University of Texas Southwestern Medical Center | Multiple Sites | 2010/10/29 | $1,163,545 |
| RP110330 | Bacterial Antitermination Elements as Synthetic Tools that Improve Production of Anticancer Compounds | RES | MacMillan, John | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/10/29 | $200,000 |
| RP110349 | Development of a novel chemogenetic approach to structure/function analysis of human telomerase RNA—a universal anticancer target | RES | Qiao, Feng | Texas A&M University | Basic Science, Multiple Sites | 2010/10/29 | $200,000 |
| RP110355 | siRNA/microRNA-conjugated gold nanoparticle dendrons for sensitizing cancer cells to chemotherapy | RES | Gunaratne, Preethi H | University of Houston | Ovary | 2010/10/29 | $199,977 |
| RP110360 | Ultra-Sensitive Multiplex Detection of Lung Cancer Biomarkers Using Immuno-Magnetic Particles | RES | Willson, Richard C | University of Houston | Lung and Bronchus | 2010/10/29 | $433,934 |
| RP110363 | PROSTATE CANCER MODEL IN ZEBRAFISH | RES | Jagadeeswaran, Pudur | University of North Texas | Prostate | 2010/10/29 | $200,000 |
| RP110383 | Dependence of small cell lung cancer on the basic helix-loop-helix transcription factors Ascl1 and NeuroD1 | RES | Cobb, Melanie H | The University of Texas Southwestern Medical Center | Lung and Bronchus, Neuroendocrine | 2010/10/29 | $1,211,342 |
| RP110390 | A functional genetic approach to identify new potential therapeutic targets for medulloblastoma. | RES | Flora, Adriano | Baylor College of Medicine | Brain and Other Nervous System, Childhood and Adolescent | 2010/10/29 | $715,305 |
| RP110394 | Identification of Novel Targets for Therapy of Pediatric Germ Cell Tumors | RES | Amatruda, James F | The University of Texas Southwestern Medical Center | Childhood and Adolescent, Ovary, Testis | 2010/10/29 | $930,533 |
| RP110395 | A genetic approach to target EWS-FLI1 oncoprotein in Ewing's Sarcoma | RES | Amatruda, James F | The University of Texas Southwestern Medical Center | Bone, Childhood and Adolescent, Sarcoma | 2010/10/29 | $197,565 |
| RP110405 | Lumen formation during blood vessel angiogenesis | RES | Cleaver, Ondine | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/10/29 | $600,000 |
| RP110412 | Biodegradable theranostic nanoparticles for detection and treatment of thyroid cancer | RES | Yang, Jian | The University of Texas at Arlington | Thyroid | 2010/10/29 | $200,000 |
| RP110430 | Biochemical Mechanisms of NF-kappaB Regulation in Cancer Cells | RES | Chen, Zhijian J | The University of Texas Southwestern Medical Center | Basic Science, Multiple Sites | 2010/10/29 | $820,097 |
| RP110441-AC | Administrative Core | RES | Ward, Elizabeth S | Texas A&M University System Health Science Center Prev. Org: The University of Texas Southwestern Medical Center Expended at Prev. Org: $232,138.34 | 2011/03/24 | $274,464.66 | |
| RP110441-C1 | C1: In vivo Imaging Core | RES | Mason, Ralph P | The University of Texas Southwestern Medical Center | 2011/03/24 | $859,684 | |
| RP110441-P1 | P1: Engineering antibodies and antibody fusion proteins that target PS to produce new generation therapeutics | RES | Ward, Elizabeth S | Texas A&M University System Health Science Center Prev. Org: The University of Texas Southwestern Medical Center Expended at Prev. Org: $991,944.03 | 2011/03/24 | $592,723.97 | |
| RP110441-P2 | P2: Analysis of the determinants of anti-tumor activity of the engineered antibodies and antibody fusions in mouse models | RES | Thorpe, Philip E | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,618,499 | |
| RP110441-P3 | P3: Defining the behavior of PS and PS-targeting agents at the cellular level | RES | Ober, Raimund J | Texas A&M University System Health Science Center Prev. Org: The University of Texas at Dallas Expended at Prev. Org: $651,710.14 | 2011/03/24 | $768,641.86 | |
| RP110444-AC | Administrative Core | RES | Gustafsson, Jan-Ake | University of Houston | 2011/03/24 | $383,428 | |
| RP110444-C1 | C1: Animal Resources Core | RES | Warner, Margaret | University of Houston | 2011/03/24 | $1,051,402 | |
| RP110444-C2 | C2: Genomics Core | RES | Webb, Paul | The Methodist Hospital Research Institute | 2011/03/24 | $495,285 | |
| RP110444-P1 | P1: Roles of Alternate Nuclear Receptors at key steps in Prostate Cancer Progression | RES | Gustafsson, Jan-Ake | University of Houston | 2011/03/24 | $1,150,497 | |
| RP110444-P2 | P2: Roles of Chaperone/beta-catenin Interactions in Prostate Cancer | RES | Cox, Marc B | The University of Texas at El Paso | 2011/03/24 | $999,992 | |
| RP110444-P3 | P3: Structural Basis of AR and NR Activation and Repression Mechanisms in Prostate Cancer | RES | Webb, Paul | The Methodist Hospital Research Institute | 2011/03/24 | $1,080,084 | |
| RP110465-AC | Administrative Core | RES | Chen, David | The University of Texas Southwestern Medical Center | 2011/03/24 | $497,513 | |
| RP110465-C2 | C2: Live Cell Imaging Core | RES | Alexandrakis, Georgios | The University of Texas at Arlington | 2011/03/24 | $789,470 | |
| RP110465-P1 | P1: Impact of DNA-PKcs phosphorylation at T2609 cluster on pathway choice for DNA double-strand break repair and tumorigenesis | RES | Chen, Benjamin P. | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,397,131 | |
| RP110465-P2 | P2: Determining the roles of SOSS complexes in DNA damage repair and tumor suppression | RES | Chen, Junjie | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,315,785 | |
| RP110465-P3 | P3: Regulation of DNA repair pathway choice by cohesin and the Smc5/6 complex | RES | Yu, Hongtao | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,397,139 | |
| RP110465-P4 | P4: Characterizing the roles of single-strand DNA-binding proteins and DNA-dependent protein kinase in homologous recombination | RES | Paull, Tanya | The University of Texas at Austin | 2011/03/24 | $1,052,630 | |
| RP110471-AC | Administrative Core | RES | Dent, Sharon | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $298,105 | |
| RP110471-C1 | C1: Tissue Culture | RES | Keyomarsi, Khandan | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,025,000 | |
| RP110471-C2 | C2: Mouse Models Core | RES | Bedford, Mark T | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $843,999 | |
| RP110471-C3 | C3: Bioinformatics | RES | Li, Wei | Baylor College of Medicine | 2011/03/24 | $1,158,522 | |
| RP110471-P1 | P1: Linking the Epigenome to Breast Cancer Etiology | RES | Dent, Sharon | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $3,531,260 | |
| RP110471-P2 | P2: Molecular Mechanisms and Functions of Epigenetic Regulators | RES | Barton, Michelle | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $2,256,383 | |
| RP110471-P3 | P3: Epigenetic Signatures of Breast Cancer Prevention | RES | Conneely, Orla M | Baylor College of Medicine | 2011/03/24 | $1,488,764 | |
| RP110486-AC | Administrative Core | RES | Schneider, Jay W | The University of Texas Southwestern Medical Center | 2011/03/24 | $390,840 | |
| RP110486-P1 | P1: Identification of Topoisomerase-II beta as the primary target of doxorubicin-induced cardiotoxicity and defining the mechanisms of action | RES | Yeh, Edward T | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,842,105 | |
| RP110486-P2 | P2: MicroRNA mechanisms and therapies to protect the heart during cancer chemotherapy | RES | Olson, Eric N | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,500,000 | |
| RP110486-P3 | P3: Maladaptive cardiomyocyte autophagy as a mechanism of doxorubicin-induced heart failure | RES | Hill, Joseph A | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,500,000 | |
| RP110486-P5 | P5: The Coronary Microvasculature as a Target for Cardioprotection for Cancer-Therapy Induced Heart Failure | RES | Schneider, Jay W | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,315,785 | |
| RP110524 | Stromal remodeling, local aromatase induction, and breast cancer risk | RES | Li, Rong | The University of Texas Health Science Center at San Antonio | Breast | 2011/03/24 | $741,446 |
| RP110532-AC | Administrative Core | RES | Davies, Peter | Texas A&M University Health Science Center Institute of Biosciences and Technology | 2011/03/24 | $2,479,350 | |
| RP110532-C1 | C1: Bioinformatics Core | RES | Wong, Stephen | The Methodist Hospital Research Institute | 2011/03/24 | $1,949,151 | |
| RP110532-C2 | C2: Education and Information Exchange Core | RES | Carson, Daniel D | Rice University | 2011/03/24 | $826,491 | |
| RP110532-P1 | P1: New Drug Discovery Program | RES | Dalby, Kevin N | The University of Texas at Austin | 2011/03/24 | $2,380,464 | |
| RP110532-P2 | P2: Combinatorial Drug Discovery Program | RES | Stephan, Clifford C | Texas A&M University Health Science Center Institute of Biosciences and Technology | 2011/03/24 | $3,865,222 | |
| RP110532-P3 | P3: Therapeutic Target Discovery Program | RES | Bartholomeusz, Geoffrey | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,114,249 | |
| RP110545 | Dendritic Cell Therapy for Prostate Cancer | RES | Decker, William | Baylor College of Medicine | Prostate | 2011/03/24 | $698,992 |
| RP110553-AC | Administrative Core | RES | Brenner, Malcolm K | Baylor College of Medicine | 2011/03/24 | $536,371 | |
| RP110553-C1 | C1: Clinical Research Core | RES | Heslop, Helen E | Baylor College of Medicine | 2011/03/24 | $1,572,036 | |
| RP110553-C2 | C2: GMP Cell and Vector Production | RES | Gee, Adrian P | Baylor College of Medicine | 2011/03/24 | $2,693,942 | |
| RP110553-C3 | C3: Immunogenomics | RES | Pascual, Maria V | Baylor Research Institute | 2011/03/24 | $390,183 | |
| RP110553-P1 | P1: Novel Therapy for Lung Cancers Using Adult Stem/Progenitor Cells | RES | Brenner, Malcolm K | Baylor College of Medicine | 2011/03/24 | $1,227,857 | |
| RP110553-P2 | P2: Adoptive T cell Immunotherapy for Glioblastoma Multiforma (GBM) | RES | Gottschalk, Stephen | Baylor College of Medicine | 2011/03/24 | $100,000 | |
| RP110553-P3 | P3: Adoptive Immunotherapy With NK Cells Expanded Ex Vivo For Treatment Of Acute Myeloid Leukemia | RES | Champlin, Richard E | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,625,600 | |
| RP110553-P4 | P4: Adoptive Cell Therapy Using Expanded Melanoma T cells Programmed Ex Vivo for Improved Efficacy In Vivo | RES | Hwu, Patrick | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $2,037,084 | |
| RP110553-P5 | P5: Novel Dendritic Cell Vaccine Therapy For Pancreatic Cancer | RES | Becerra, Carlos | Baylor Research Institute | 2011/03/24 | $1,717,997 | |
| RP110555 | Activation of Prostate Cancer Stem Cells Through Aberrant FGF Signaling | RES | Wang, Fen | Texas A&M University System Health Science Center | Prostate | 2011/03/24 | $798,945 |
| RP110562-AC | Administrative Core | RES | Choy, Hak | The University of Texas Southwestern Medical Center | 2011/03/24 | $595,713 | |
| RP110562-C1 | C1: Biostatistics | RES | Ahn, Chul | The University of Texas Southwestern Medical Center | 2011/03/24 | $588,474 | |
| RP110562-C2 | C2: Quality Assurance Core | RES | Court, Laurence E | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $840,699 | |
| RP110562-P1 | P1: Realizing Technological Advances: The State of Texas Advanced Radiation Therapy (START) Trials | RES | Timmerman, Robert D | The University of Texas Southwestern Medical Center | 2011/03/24 | $2,356,538 | |
| RP110562-P2 | P2: Advanced Volumetric Imaging and Adaptive Radiotherapy for Detecting and Correcting for Inter-fractional Changes | RES | Yang, Jinzhong | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,558,477 | |
| RP110584 | PTEN-loss enriched Akt inhibition clinical study in colorectal cancer | RES | Kopetz, Scott | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2011/03/24 | $830,765 |
| RP110595-AC | Administrative Core | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $275,259 | |
| RP110595-C1 | C1: Pathology Core | RES | Liu, Jinsong | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $829,285 | |
| RP110595-C2 | C2: Biostatistics and Bioinformatics Core | RES | Baggerly, Keith | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $558,852 | |
| RP110595-P1 | P1: Enhancing Primary Paclitaxel Sensitivity With Kinase Specific RNAi | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,388,805 | |
| RP110595-P2 | P2: Circumventing Primary Carboplatin Resistance using siRNA and miRNA Transfer | RES | Sood, Anil K | The University of Texas M.D. Anderson Cancer Center | 2011/03/24 | $1,516,026 | |
| RP110595-P3 | P3: Mapping the Landscape of Conditional Vulnerabilities in Ovarian Cancer | RES | White, Michael A | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,397,137 | |
| RP110609 | Targeting the CXCR4 chemokine receptor: a new approach to overcome stromal cell-mediated drug resistance in Acute Lymphoblastic Leukemia (ALL) | RES | Burger, Jan A | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2011/03/24 | $723,246 |
| RP110708-AC | Administrative Core | RES | McKnight, Steven L | The University of Texas Southwestern Medical Center | 2011/03/24 | $658,755 | |
| RP110708-C1 | C1: Sequencing Core | RES | Wheeler, David | Baylor College of Medicine | 2011/03/24 | $2,022,424 | |
| RP110708-C2 | C2: HTS Core | RES | Posner, Bruce A | The University of Texas Southwestern Medical Center | 2011/03/24 | $2,206,362 | |
| RP110708-C3 | C3: Pharmacology Core | RES | Williams, Noelle S | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,315,786 | |
| RP110708-P1 | P1: Molecular Biomarker ID | RES | Minna, John | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,972,269 | |
| RP110708-P2 | P2: Compound Target ID | RES | White, Michael A | The University of Texas Southwestern Medical Center | 2011/03/24 | $2,845,411 | |
| RP110708-P3 | P3: Chemistry | RES | Ready, Joseph M | The University of Texas Southwestern Medical Center | 2011/03/24 | $1,998,363 | |
| RP110763-AC | Administrative Core | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | 2011/03/24 | $261,482 | |
| RP110763-C1 | C1: Biobanking of Cell Lines and Xenografts | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | 2011/03/24 | $791,473 | |
| RP110763-P1 | P1: Establishing New Validated Cancer Cell Lines In Vitro | RES | Gazdar, Adi F | The University of Texas Southwestern Medical Center | 2011/03/24 | $750,514 | |
| RP110763-P3 | P3: Establishing and Charactierizing New Cancer Direct Xenografts | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | 2011/03/24 | $913,931 | |
| RP110771 | Acquisition of a Biomedical Cyclotron and Development of a Comprehensive Positron Emission Tomography Program at UT Southwestern for Cancer Research | RES | Sun, Xiankai | The University of Texas Southwestern Medical Center | All Sites | 2011/03/24 | $4,200,000 |
| RP110776 | NIR/Visible/UV FACS for Molecular Medicine | RES | Sevick, Eva M | The University of Texas Health Science Center at Houston | All Sites | 2011/03/24 | $598,472 |
| RP110782 | LTQ Orbitrap Velos Mass Spectrometer to Support Cancer Research | RES | Person, Maria D | The University of Texas at Austin | All Sites | 2011/03/24 | $1,302,789 |
| RP110784 | A Mass spectrometer for transcrption factor and protein ubiquitination profiling in cancer cells upon drug treatment | RES | Qin, Jun | Baylor College of Medicine | All Sites | 2011/03/24 | $2,440,429 |
| RP110786 | Multiphoton Laser Scanning Microscope for Cancer Research and Drug Discovery | RES | Smith, Quentin R | Texas Tech University Health Sciences Center | Brain and Other Nervous System, Breast, Colorectal, Kidney and Renal Pelvis, Leukemia, Lung and Bronchus, Pancreas, Prostate | 2011/03/24 | $928,916 |
| RP120016 | Small molecule inhibitors of proteasome assembly: a new strategy for cancer therapy | RES | DeMartino, George N | The University of Texas Southwestern Medical Center | All Sites | 2011/11/02 | $200,000 |
| RP120028 | Targeting prostaglandin substrate availability in colon cancer: Characterization of a novel arachidonic acid-deficient mouse model | RES | Chapkin, Robert S | Texas Agrilife Research | Colorectal | 2011/11/02 | $199,999 |
| RP120046 | Mining the oncogenome: Functional genomics approaches for screening mutation drivers of pancreatic ductal adenocarcinoma. | RES | Scott, Kenneth L | Baylor College of Medicine | All Sites, Pancreas | 2011/11/02 | $803,179 |
| RP120052 | Super-high resolution imaging of tumor angiogenesis in deep tissue | RES | Yuan, Baohong | The University of Texas at Arlington | Breast, Head and Neck, Prostate, Skin, Thyroid | 2011/11/02 | $1,095,905 |
| RP120053 | Beam-Scanning Radar for Tumor Tracking in Lung Cancer Radiotherapy | RES | Li, Changzhi | Texas Tech University | Lung and Bronchus | 2011/11/02 | $199,994 |
| RP120076 | Novel mechanisms leading to telomere dysfunction and cancer predisposition | RES | Bertuch, Alison A | Baylor College of Medicine | Head and Neck, Leukemia | 2011/11/02 | $937,896 |
| RP120092 | Proteomics and Metabolomics Core Facility | RES | Edwards, Dean P | Baylor College of Medicine | All Sites | 2011/11/02 | $6,000,000 |
| RP120093 | Protein Palmitoyltransferases as Novel Therapeutic Targets for Acquired Lung Cancer Vulnerabilities | RES | Hofmann, Sandra L | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2011/11/02 | $200,000 |
| RP120094 | Turn ON the Tumor Contrast for Surgical Resection of Head and Neck Cancers | RES | Gao, Jinming | The University of Texas Southwestern Medical Center | Head and Neck | 2011/11/02 | $965,257 |
| RP120108 | Improving on Anti-CTLA-4 Therapy | RES | Sharma, Padmanee | The University of Texas M.D. Anderson Cancer Center | All Sites | 2011/11/02 | $1,378,796 |
| RP120124 | Investigating the roles of p63 in miRNA regulation in EMT and metastatic breast cancer | RES | Flores, Elsa R | The University of Texas M.D. Anderson Cancer Center | Breast | 2011/11/02 | $1,137,202 |
| RP120138 | Nuclear receptors and Hippo signaling in liver cancer | RES | Moore, David D | Baylor College of Medicine | Liver and Intrahepatic Bile Duct | 2011/11/02 | $1,214,977 |
| RP120168 | Identification of Rheb and Notch-dependent Pathways in Tuberous Sclerosis Complex | RES | Karbowniczek, Magdalena | Texas Tech University Health Sciences Center | Brain and Other Nervous System, Kidney and Renal Pelvis, Lung and Bronchus | 2011/11/02 | $756,644 |
| RP120190 | Oncometabolites in Renal Cancer | RES | Block, Karen | The University of Texas Health Science Center at San Antonio | Kidney and Renal Pelvis | 2011/11/02 | $199,902 |
| RP120194 | Defining and Subverting Allele-Specific Regulatory Networks in Cancer | RES | Iyer, Vishwanath R | The University of Texas at Austin | Brain and Other Nervous System | 2011/11/02 | $1,125,799 |
| RP120214 | Clinical Translation of Therapeutic siRNA in Solid Malignancies | RES | Coleman, Robert L | The University of Texas M.D. Anderson Cancer Center | All Sites, Ovary | 2011/11/02 | $1,379,098 |
| RP120217 | Role of IL-17 family cytokines in colon inflammation and cancer | RES | Dong, Chen | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2011/11/02 | $1,285,789 |
| RP120241 | T-Cell Therapy After Hematopoietic Stem Cell Transplantation | RES | Cooper, Laurence | The University of Texas M.D. Anderson Cancer Center | Leukemia, Lymphoma | 2011/11/02 | $1,359,672 |
| RP120256 | Identify signature profile for sensitivity/resistance to PI3K pathway inhibitors to predict response to therapy in Glioblastoma. | RES | Yung, W. K. Alfred | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2011/11/02 | $1,000,179 |
| RP120258 | Towards Personalized Cancer Therapy: Stratification of Oral and Pharyngeal Cancer Based on p53 Mutational Status | RES | Myers, Jeffrey | The University of Texas M.D. Anderson Cancer Center | Head and Neck | 2011/11/02 | $1,139,807 |
| RP120262 | Functional and structural characterization of small chemical compounds that arrest glioma stem cell growth with high activity and specificity | RES | Parada, Luis F | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2011/11/02 | $1,499,532 |
| RP120280 | Chemoprevention of Colon Cancer by Targeting APC-deficient Cells for Apoptosis | RES | Wu, Xiangwei | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2011/11/02 | $790,550 |
| RP120290 | Targeting hedgehog pathway for prostate cancer treatment | RES | Sun, Luzhe | The University of Texas Health Science Center at San Antonio | Prostate | 2011/11/02 | $884,089 |
| RP120298 | Chimeric T cells for therapy of Hodgkin Lymphomas and CD30+ Non Hodgkin Lymphomas | RES | Ramos, Carlos | Baylor College of Medicine | Lymphoma | 2011/11/02 | $905,975 |
| RP120307 | Factors Influencing Telomerase Action (Assembly, Modification, Recruitment, Activation): Potential Targets for Telomerase Inhibition Cancer Therapy | RES | Wright, Woodring E | The University of Texas Southwestern Medical Center | All Sites | 2011/11/02 | $1,002,052 |
| RP120311 | Regulation of Cyclooxygenase-2 (COX-2) Gene Expression by Noncoding RNAs in Cancer | RES | Janowski, Bethany A | The University of Texas Southwestern Medical Center | Colorectal, Lung and Bronchus | 2011/11/02 | $631,578 |
| RP120314 | Engineering and Preliminary Evaluation of a Fully Human, Non-Immunogenic Asparaginase For the Treatment of L-Asn Auxotrophic Cancers | RES | Georgiou, George | The University of Texas at Austin | Leukemia, Ovary, Pancreas | 2011/11/02 | $200,000 |
| RP120316 | CBM complex-mediated signaling pathways as potential therapeutic targets for EGFR-induced cancer | RES | Lin, Xin | The University of Texas M.D. Anderson Cancer Center | All Sites | 2011/11/02 | $915,974 |
| RP120326 | In-Situ PET Imaging for Adaptive Proton Therapy | RES | Shao, Yiping | The University of Texas M.D. Anderson Cancer Center | All Sites | 2011/11/02 | $1,271,284 |
| RP120340 | Arginine Methylation Link to HPV-16-Induced Cervical Cancer | RES | Chiang, Cheng-Ming | The University of Texas Southwestern Medical Center | Cervix Uteri | 2011/11/02 | $200,000 |
| RP120343 | Gli Transcriptional Activity in Basal Cell Carcinomas | RES | Vokes, Steven A | The University of Texas at Austin | Brain and Other Nervous System, Skin | 2011/11/02 | $659,495 |
| RP120348 | The University of Texas MD Anderson Cancer Center Science Park Next-Generation Sequencing Facility | RES | Shen, Jianjun | The University of Texas M.D. Anderson Cancer Center | Breast, Leukemia, Pancreas, Prostate, Skin | 2011/11/02 | $5,995,917 |
| RP120352 | Mechanisms of CRM1-mediated nuclear export in cancer | RES | Chook, Yuh Min | The University of Texas Southwestern Medical Center | All Sites, Bone, Breast, Colorectal, Leukemia, Myeloma, Ovary | 2011/11/02 | $684,209 |
| RP120372 | A next-generation sequencing strategy to identify chromosomal translocations targeting the immunoglobulin loci in B-cell malignancies | RES | Aguiar, Ricardo | The University of Texas Health Science Center at San Antonio | Leukemia, Lymphoma, Myeloma | 2011/11/02 | $200,000 |
| RP120380 | Distinct microRNAs Regulate Prostate Cancer Stem Cells | RES | Tang, Dean G | The University of Texas M.D. Anderson Cancer Center | Prostate | 2011/11/02 | $750,000 |
| RP120390 | Control of cross-talk between ovarian cancer cells and the tumor microenvironment | RES | Naora, Honami | The University of Texas M.D. Anderson Cancer Center | Ovary | 2011/11/02 | $727,029 |
| RP120393 | Preclinical Development of Texaphyrin-Platinum Conjugates | RES | Sessler, Jonathan | The University of Texas at Austin | Lung and Bronchus, Ovary | 2011/11/02 | $1,275,000 |
| RP120394 | Molecular Oncogenesis of NANOG in Castration-Resistant Prostate Cancer | RES | Jeter, Collene R | The University of Texas M.D. Anderson Cancer Center | Prostate | 2011/11/02 | $664,248 |
| RP120406 | A New Role for Triptan Drugs in the Treatment of Breast Cancer | RES | Dalby, Kevin N | The University of Texas at Austin | Breast | 2011/11/02 | $1,010,289 |
| RP120408 | Anti-Cancer Drugs to Treat Cancer Pain | RES | Gutstein, Howard | The University of Texas M.D. Anderson Cancer Center | All Sites | 2011/11/02 | $913,322 |
| RP120422 | Simultaneous Vascular Targeting and Tumor Targeting of Cerebral Breast Cancer Metastases Using a T Cell Receptor Mimic Antibody | RES | Bickel, Ulrich | Texas Tech University Health Sciences Center | Brain and Other Nervous System, Breast | 2011/11/02 | $199,967 |
| RP120429 | A Lentivirus-Mediated Dual Library, Dual Selection Approach for the Identification of Surface Biomarkers and Antibodies Specific to Cancer Cells | RES | Chen, Zhilei | Texas A&M University | All Sites, Colorectal | 2011/11/02 | $200,000 |
| RP120451 | Novel Strategy for Treatment of HER2-Positive Breast Cancer | RES | Claret, Francois X | The University of Texas M.D. Anderson Cancer Center | Breast | 2011/11/02 | $864,748 |
| RP120459 | Contribution of the BRIGHT transcription factor to autoimmune Diffuse Large B-cell Lymphoma | RES | Tucker, Philip W | The University of Texas at Austin | Lymphoma | 2011/11/02 | $947,367 |
| RP120462 | Environmental Determinants of Hepatocellular Carcinoma in South Texas | RES | Pollock, Bradley H | The University of Texas Health Science Center at San Antonio | Liver and Intrahepatic Bile Duct | 2011/11/02 | $767,107 |
| RP120474 | Enabling the structure determination of functional human telomerase holoenzyme | RES | Jiang, Qiu-Xing | The University of Texas Southwestern Medical Center | All Sites | 2011/11/02 | $681,709 |
| RP120489 | Transporter-Targeted Drug Delivery and Treatment of Brain Metastases of Breast Cancer | RES | Smith, Quentin R | Texas Tech University Health Sciences Center | Brain and Other Nervous System, Breast | 2011/11/02 | $736,685 |
| RP120495 | North Texas Clinical Pharmacology Cancer Core | RES | Leff, Richard | Texas Tech University Health Sciences Center | All Sites | 2011/11/02 | $2,500,000 |
| RP120505 | Clinical and molecular characterization of combined BRAF and MEK inhibitor treatment in patients with metastatic melanoma resistant to BRAF inhibitor alone | RES | Davies, Michael A | The University of Texas M.D. Anderson Cancer Center | Skin | 2011/11/02 | $1,016,800 |
| RP120507 | Massively Parallel Protein Identification for Cancer Biomarker Discovery | RES | Marcotte, Edward M | The University of Texas at Austin | All Sites | 2011/11/02 | $199,927 |
| RP120510 | Investigational New Drug Production Core Facility at Scott and White Cancer Research Institute | RES | Woo, Jung H | Scott and White Healthcare | All Sites | 2011/11/02 | $3,584,521 |
| RP120528 | Establishing a Cancer Clinical Research Core facility at Texas Tech University Health Science Center in El Paso | RES | Nahleh, Zeina | Texas Tech University Health Sciences Center at El Paso | All Sites | 2011/11/02 | $1,500,000 |
| RP120558 | Development of a Novel High-resolution Photoacoustic Microscopy System for Noninvasive in vivo Imaging of Melanoma | RES | Ye, Jing Yong | The University of Texas at San Antonio | Skin | 2011/11/02 | $698,120 |
| RP120572 | Development of cancer traps for prolonging lifespan by eliminating metastatic cancer cells | RES | Tang, Liping | The University of Texas at Arlington | All Sites | 2011/11/02 | $200,000 |
| RP120583 | A New Functional Genomics Approach to Discovering Therapeutic Targets for Breast Cancer | RES | Westbrook, Thomas | Baylor College of Medicine | All Sites, Breast | 2011/11/02 | $1,102,029 |
| RP120588 | Targeting the Acidic Tumor Microenvironment with Renal Clearable and pH Responsive Luminescent Gold Nanoparticles | RES | Zheng, Jie | The University of Texas at Dallas | All Sites | 2011/11/02 | $1,259,790 |
| RP120611 | Small Animal Cancer Imaging Core | RES | Motamedi, Massoud | The University of Texas Medical Branch at Galveston | All Sites | 2011/11/02 | $578,204 |
| RP120613 | Develop cutting-edge proteomics core facility based on high resolution, high accuracy mass spectrometry and high throughput, web-based bioinformatics technology | RES | Mirzaei, Hamid | The University of Texas Southwestern Medical Center | All Sites | 2011/11/02 | $4,400,000 |
| RP120617 | Advanced in vivo imaging of tumor initiation and progression | RES | Gustafsson, Jan-Ake | University of Houston | All Sites | 2011/11/02 | $990,286 |
| RP120670-AC | Administrative Core | RES | Timmerman, Robert D | The University of Texas Southwestern Medical Center | 2012/08/02 | $310,602 | |
| RP120670-C1 | C1: Biostatistical | RES | Ahn, Chul | The University of Texas Southwestern Medical Center | 2012/08/02 | $269,129 | |
| RP120670-C3 | C3: Image Guided Irradiation of Small Animals | RES | Saha, Debabrata | The University of Texas Southwestern Medical Center | 2012/08/02 | $887,912 | |
| RP120670-P3 | P3: Effects of Hypoxia | RES | Mason, Ralph P | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,298,237 | |
| RP120670-P4 | P4: Radiation-Guided Vascular Targeting of Lung Cancer | RES | Brekken, Rolf | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,353,233 | |
| RP120685-AC | Administrative Core | RES | Skapek, Stephen X | The University of Texas Southwestern Medical Center | 2012/08/02 | $666,202 | |
| RP120685-C1 | C1: Central Sarcoma Processing Core | RES | Amatruda, James F | The University of Texas Southwestern Medical Center | 2012/08/02 | $848,328 | |
| RP120685-C2 | C2: Functional Genomics and Computation Core | RES | Chen, Yidong | The University of Texas Health Science Center at San Antonio | 2012/08/02 | $816,645 | |
| RP120685-P1 | P1: Identification of Actionable Mutations in STS and ESFT Tumors | RES | Parsons, Donald | Baylor College of Medicine | 2012/08/02 | $1,478,447 | |
| RP120685-P2 | P2: High Throughput Screening for Sarcoma Cell Proliferation and Survival Factors | RES | Skapek, Stephen X | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,381,464 | |
| RP120685-P3 | P3: Functional Validation of Actionable Mutations in Sarcoma Genetic Model Systems | RES | Amatruda, James F | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,727,162 | |
| RP120713-AC | Administrative Core | RES | Kurie, Jonathan M | The University of Texas M.D. Anderson Cancer Center | 2012/08/02 | $530,913 | |
| RP120713-C2 | C2: Biostatistics and Bioinformatics. | RES | Creighton, Chad J | Baylor College of Medicine | 2012/08/02 | $556,969 | |
| RP120713-C3 | Core 3 | RES | Wistuba, Ignacio | The University of Texas M.D. Anderson Cancer Center | 2012/08/02 | $530,913 | |
| RP120713-P1 | P1: Cancer-associated Fibroblasts in Lung Cancer Invasion. | RES | Kurie, Jonathan M | The University of Texas M.D. Anderson Cancer Center | 2012/08/02 | $1,300,007 | |
| RP120713-P2 | P2: Tumor Cell-extracellular Matrix (ECM) Interactions as Drivers of Tumor Invasion and Metastasis. | RES | Grande-Allen, Kathryn | Rice University | 2012/08/02 | $1,395,844 | |
| RP120713-P3 | P3: Influence of Tumor Microenvironment on Angiogenesis. | RES | Dickinson, Mary E | Baylor College of Medicine | 2012/08/02 | $1,061,827 | |
| RP120715-AC | Administrative Core | RES | Tomlinson, G. E. | The University of Texas Health Science Center at San Antonio | 2012/08/02 | $80,832 | |
| RP120715-C2 | C2: Pathology Core A | RES | Finegold, Milton | Baylor College of Medicine | 2012/08/02 | $42,106 | |
| RP120715-C4 | C4: Bioinformatics and Biostatistics | RES | Chen, Yidong | The University of Texas Health Science Center at San Antonio | 2012/08/02 | $252,964 | |
| RP120715-P2 | P2: Genomic characterization of hepatoblastoma using massively-parallel DNA sequencing | RES | Parsons, Donald | Baylor College of Medicine | 2012/08/02 | $142,200 | |
| RP120717-AC | Administrative Core | RES | Liu, Zhi-Ping | The University of Texas Southwestern Medical Center | 2012/08/02 | $234,865 | |
| RP120717-C1 | C1: Translational Core | RES | Hsieh, Jer-Tsong | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,049,969 | |
| RP120717-P1 | P1: Targeting epigenetic co-activators of AR with small molecule inhibitors | RES | Liu, Zhi-Ping | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,046,080 | |
| RP120717-P2 | P2: Mechanism and inhibition of LSD1-dependent transcription of AR target genes in prostate cancer cells | RES | Yu, Hongtao | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,394,990 | |
| RP120717-P3 | P3: Molecular and Structural basis of epigenetic regulation of AR | RES | Rizo-Rey, Jose | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,315,785 | |
| RP120717-P4 | P4: Rational design of peptidomimetics that target the lysine demethylases and their binding to the androgen receptor in prostate cancer | RES | Ahn, Jung-Mo | The University of Texas at Dallas | 2012/08/02 | $1,315,785 | |
| RP120718-AC | Administrative Core | RES | Fontoura, Beatriz | The University of Texas Southwestern Medical Center | 2012/08/02 | $394,735 | |
| RP120718-C1 | C1: Chemistry and Pharmacology Core | RES | De Brabander, Jef K | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,049,850 | |
| RP120718-C2 | C2: Proteomics Core | RES | Chen, Zhijian J | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,766,633 | |
| RP120718-P1 | P1: Selective autophagy molecules as multifunctional regulators of innate immunity and oncogenesis | RES | Levine, Beth C | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,576,248 | |
| RP120718-P2 | P2: Intersections between viral-host interactions and oncogenic pathways as molecular targets for chemical intervention | RES | Fontoura, Beatriz | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,578,945 | |
| RP120718-P3 | P3: Mechanisms underlying inflammation and cell death in cancer | RES | Chen, Zhijian J | The University of Texas Southwestern Medical Center | 2012/08/02 | $1,556,413 | |
| RP120727 | Development of a targeted therapy: a treatment that is able to suppress breast cancer initiating cells | RES | Hung, Mien-Chie | The University of Texas M.D. Anderson Cancer Center | Breast | 2012/03/29 | $999,872 |
| RP120732-AC | Administrative Core | RES | Mangelsdorf, David | The University of Texas Southwestern Medical Center | 2012/08/02 | $280,715 | |
| RP120732-C1 | C1: Molecular Pathology and Biomarker Core. | RES | Wistuba, Ignacio | The University of Texas M.D. Anderson Cancer Center | 2012/08/02 | $775,000 | |
| RP120732-C2 | C2: Biostatistics, Bioinformatics and Database Core | RES | Xie, Yang | The University of Texas Southwestern Medical Center | 2012/08/02 | $749,940 | |
| RP120732-P1 | P1: Characterization of Nuclear Receptor and Co-regulator Expression and Function in Lung Cancers | RES | Minna, John | The University of Texas Southwestern Medical Center | 2012/08/02 | $2,057,582 | |
| RP120732-P2 | P2: Characterization of Nuclear Receptor and Co-regulator Expression and Function in Breast Cancers | RES | Fuqua, Suzanne A | Baylor College of Medicine | 2012/08/02 | $1,397,662 | |
| RP120732-P3 | P3: Characterization of Cancer-specific Gene Programs Regulated by Nuclear Receptors and Co-regulators | RES | Kittler, Ralf | The University of Texas Southwestern Medical Center | 2012/08/02 | $800,020 | |
| RP120732-P4 | P4: Development of Nuclear Receptor and Coregulator-based Therapies for Breast and Lung Cancers | RES | O'Malley, Bert | Baylor College of Medicine | 2012/08/02 | $955,045 | |
| RP120732-P5 | P5: Characterization of Nuclear Receptors and Coregulators in Breast Cancer Mouse Models as Targets for New Therapeutic Development | RES | Xu, Jianming | Baylor College of Medicine | 2012/08/02 | $1,200,000 | |
| RP120777 | P4: Will Suppressing Mast Cell Function Improve Immunotherapy for Pancreatic Cancer? | RES | Ullrich, Stephen E | The University of Texas M.D. Anderson Cancer Center | Sarcoma | 2012/03/29 | $778,431 |
| RP120840 | P1: Enhancing the Identification of Markers and Potential Therapeutic Targets for Improving Tumor Response via MIRNA and DNA Methylation Analysis | RES | Story, Michael D | The University of Texas Southwestern Medical Center | Head and Neck | 2012/03/29 | $851,490 |
| RP120855 | P1: Targeting Cellular Energetics Pathways in Endometrial Cancer | RES | Walker, Cheryl | Texas A&M University System Health Science Center | Corpus and Uterus, NOS | 2012/03/29 | $1,455,000 |
| RP120867 | An NMR resource for enhancing the discovery of novel cancer therapeutics at the University of Texas Health Science Center at San Antonio | RES | Ivanov, Dimitri | The University of Texas Health Science Center at San Antonio | All Sites | 2012/03/29 | $1,082,063 |
| RP120880 | Eliminating Cancer Pain by Growth Factor Inhibition | RES | Gutstein, Howard | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/03/29 | $999,999 |
| RP120897 | ß-Lapachone Nanotherapeutics for NQO1-Targeted Therapy of Cancer | RES | Gao, Jinming | The University of Texas Southwestern Medical Center | Lung and Bronchus, Sarcoma | 2012/03/29 | $999,597 |
| RP120941 | NIR fluorescence imaging for assessment of lymphatics in cancer treatment and recovery | RES | Sevick, Eva M | The University of Texas Health Science Center at Houston | Head and Neck | 2012/03/29 | $605,425 |
| RP120960 | P1: Coordination of inputs from taste receptors and the Ras/ERK1/2 axis to mTORC1: Mechanisms and pathway interactions in cancer. | RES | Cobb, Melanie H | The University of Texas Southwestern Medical Center | Multiple Sites | 2012/03/29 | $1,215,000 |
| RP120997 | The University of Texas MD Anderson Cancer Center Science Park Integrated Optical Imaging and Computerized Tomography System for Small Animals | RES | Kusewitt, Donna F | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/03/29 | $659,675 |
| RP121002 | Examination of the Pharmacological Properties of a Novel Antifungal Named Occidiofungin | RES | Smith, James | Texas A&M University | All Sites | 2012/03/29 | $777,884 |
| RP121010 | CyTOF Mass Cytometer and Element Tagging System | RES | Andreeff, Michael | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/03/29 | $1,223,725 |
| RP121018 | Rapid and sensitive diagnostic testing for somatic mutations in cancer | RES | Wheeler, David | Baylor College of Medicine | All Sites | 2012/03/29 | $996,815 |
| RP121035 | Development and Pre-clinical Testing of Therapeutic MYCN Vaccine | RES | Metelitsa, Leonid S | Baylor College of Medicine | Other | 2012/03/29 | $1,023,174 |
| RP121048 | Development of therapeutic vaccines/drugs against prostate cancer by Blocking immune suppression | RES | Wang, Rongfu | The Methodist Hospital Research Institute | Prostate | 2012/03/29 | $904,131 |
| RP121060 | Manufacture, Formulation, and IND-directed Toxicology of the Multifunctional Ceramide Catabolism Inhibitor D-threo-PPMP to enable Phase I Clinical Trials | RES | Maurer, Barry J | Texas Tech University Health Sciences Center | Multiple Sites | 2012/03/29 | $1,000,000 |
| RP121071 | Development Of Multistage Vectored siRNA Therapeutics For The Treatment Of Breast Cancer | RES | Ferrari, Mauro | The Methodist Hospital Research Institute | Breast | 2012/03/29 | $999,834 |
| RP130020 | Investigating PI3K inhibition-mediated feedback regulation in renal cancer treatment | RES | Gan, Boyi | The University of Texas M.D. Anderson Cancer Center | Kidney and Renal Pelvis, Other | 2012/12/05 | $826,196 |
| RP130051 | Impact of Health Insurance on Racial Disparities in Cancer Screening, Diagnosis, Treatment and Survival in Texas | RES | Du, Xianglin L | The University of Texas Health Science Center at Houston | Breast, Colorectal | 2012/12/05 | $435,049 |
| RP130054 | Genes and Pathways Cooperating with p53 in LFS Tumorigenesis | RES | Krahe, Ralf | The University of Texas M.D. Anderson Cancer Center | Bone | 2012/12/05 | $1,452,982 |
| RP130059 | K-ras Spatiotemporal Dynamics: Novel Therapeutic Targets | RES | Hancock, John F | The University of Texas Health Science Center at Houston | Colorectal, Corpus and Uterus, NOS, Lung and Bronchus, Pancreas | 2012/12/05 | $1,050,000 |
| RP130078 | Dissecting the role of IL-17 mediated inflammation as a preventive and therapeutic target in lung carcinogenesis | RES | Chang, Seon Hee | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2012/12/05 | $802,933 |
| RP130090 | Personalized risk assessment for families with Li-Fraumeni Syndrome | RES | Wang, Wenyi | The University of Texas M.D. Anderson Cancer Center | Bone, Brain and Other Nervous System, Breast | 2012/12/05 | $484,412 |
| RP130109 | Quantitative Cone-beam CT for Adaptive Radiation Therapy | RES | Wang, Jing | The University of Texas Southwestern Medical Center | All Sites | 2012/12/05 | $676,134 |
| RP130123 | Using Deep Sequencing Technology to Study Genes & Behavioral Phenotypes Related to Smoking Cessation, Negative affect & Nicotine Withdrawal | RES | Cinciripini, Paul M | The University of Texas M.D. Anderson Cancer Center | Bladder, Bladder, Cervix Uteri, Colorectal, Head and Neck, Larynx, Lung and Bronchus, Pancreas | 2012/12/05 | $1,241,316 |
| RP130124 | Deep sequencing oncoviral evolvomes as a personalized cancer diagnostic tool | RES | Barrick, Jeffrey E | The University of Texas at Austin | Cervix Uteri | 2012/12/05 | $260,633 |
| RP130135 | Comprehensive identification of all human Ras effectors to define mechanisms of Ras-induced malignancy and potential drug targets | RES | Chang, Eric C | Baylor College of Medicine | All Sites | 2012/12/05 | $199,994 |
| RP130145 | Osteoclast Regulation of Bone Metastasis of Cancer | RES | Wan, Yihong | The University of Texas Southwestern Medical Center | Bone, Breast | 2012/12/05 | $1,081,815 |
| RP130166 | Engineering membrane toxic C-type lectins for tumor targeting | RES | Hooper, Lora V | The University of Texas Southwestern Medical Center | All Sites | 2012/12/05 | $200,000 |
| RP130172 | Exploiting synthetic lethality, drug synergy, and an animal model reproducing drug sensitivities in humans to identify small molecules to treat renal cancer | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2012/12/05 | $199,994 |
| RP130189 | Development of Therapeutics Targeting Truncated Adenomatous Polyposis Coli (APC) as a Novel Prevention and Intervention Strategy for Colorectal Cancer | RES | Shay, Jerry W | The University of Texas Southwestern Medical Center | Colorectal | 2012/12/05 | $400,000 |
| RP130212 | A molecularly targeted anticancer therapeutic strategy premised upon attack of aberrant Wnt pathway responses | RES | Lum, Lawrence | The University of Texas Southwestern Medical Center | Colorectal, Leukemia | 2012/12/05 | $1,389,624 |
| RP130219 | The cephalostatin/ritterazine antineoplastics; Synthesis, activity, and structural and mechanistic studies of novel cancer-selective chemotherapeutics | RES | Lee, Seongmin | The University of Texas at Austin | All Sites | 2012/12/05 | $955,094 |
| RP130256 | Texas Assistance for Cancer Cell Therapy (TACCT) | RES | Gee, Adrian P | Baylor College of Medicine | All Sites | 2012/12/05 | $5,300,000 |
| RP130258 | Tumor cell lytic peptoids that target exposed phosphatidylserine | RES | Udugamasooriya, Damith G | University of Houston Prev. Org: The University of Texas Southwestern Medical Center Expended at Prev. Org: $39,985.87 | Brain and Other Nervous System, Breast, Leukemia, Lung and Bronchus, Prostate | 2012/12/05 | $735,629.13 |
| RP130266 | Rational Redox-Driven Non-Toxic Therapeutic Strategies For Pediatric Brain Cancers (Carson Leslie Award) | RES | Srivenugopal, Kalkunte S | Texas Tech University Health Sciences Center | Brain and Other Nervous System | 2012/12/05 | $777,268 |
| RP130272 | The metabolic phenome of human lung cancer. | RES | DeBerardinis, Ralph J | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2012/12/05 | $665,559 |
| RP130276 | The mTOR-dependent nuclear transport in cancer | RES | Sarbassov, Dos | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/12/05 | $929,920 |
| RP130293 | Minimally-invasive intratumoral drug delivery using micronedles to treat oral squamous carcinomas | RES | Gill, Harvinder S | Texas Tech University | Head and Neck | 2012/12/05 | $199,910 |
| RP130297 | Inhibition of DNA polymerase theta (POLQ) for radiosensitization of breast cancer | RES | Wood, Richard D | The University of Texas M.D. Anderson Cancer Center | Breast | 2012/12/05 | $450,000 |
| RP130310 | Regulation of HECT E3 ubiquitin ligases by Rak kinase: a novel mechanism that links tyrosine phosphorylation to protein stability in breast tumor suppression | RES | Lin, Shiaw-Yih | The University of Texas M.D. Anderson Cancer Center | Breast | 2012/12/05 | $788,915 |
| RP130312 | Development of optogenetic tools for cellular and in vivo manipulation of cancer pathways | RES | Rice, Luke | The University of Texas Southwestern Medical Center | All Sites | 2012/12/05 | $199,688 |
| RP130315 | Inhibition of TGFb signaling by nuclear receptor COUP-TFII results in aggressive prostate cancer growth and metastasis | RES | Tsai, Ming-Jer | Baylor College of Medicine | Prostate | 2012/12/05 | $750,000 |
| RP130362 | Imaging cancerous tissues with liposomal MRI contrast agents that utilize bioengineered nanovalves | RES | Blount, Paul | The University of Texas Southwestern Medical Center | All Sites | 2012/12/05 | $1,247,260 |
| RP130368 | Proton Beam Radiation Therapy vs. Conventional Beam Radiation Therapy: Toxicities During & After Craniospinal Radiation Therapy in Children (Carson Leslie Award) | RES | Ris, M Douglas | Baylor College of Medicine | Brain and Other Nervous System | 2012/12/05 | $1,189,121 |
| RP130372 | The Influence of Tumor Stiffness on Therapeutic Efficacy | RES | Suggs, Laura J | The University of Texas at Austin | Breast | 2012/12/05 | $837,947 |
| RP130389 | Targeting the Warburg effect for human cancer treatment | RES | Lu, Zhimin | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2012/12/05 | $199,639 |
| RP130397 | A Proteomics and Metabolomics Core Facility at the University of Texas MD Anderson Cancer Center | RES | Weinstein, John N | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/12/05 | $4,500,000 |
| RP130409 | COMMD1 and the Control of Tumor Invasion | RES | Burstein, Ezra | The University of Texas Southwestern Medical Center | All Sites, Colorectal | 2012/12/05 | $812,300 |
| RP130412 | Image-Guided Ultrafast Laser Scalpel for Precise, Selective, and Minimally Invasive Cancer Surgery | RES | Ben-Yakar, Adela | The University of Texas at Austin | Head and Neck, Larynx | 2012/12/05 | $1,246,931 |
| RP130425 | Elucidating Mechanisms of Altered Lipid Metabolism in Cancer | RES | Du, Guangwei | The University of Texas Health Science Center at Houston | All Sites | 2012/12/05 | $200,000 |
| RP130427 | Clinical MR spectroscopy development of 2-hydroxyglutarate as a specific biomarker for malignant gliomas | RES | Choi, Changho | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2012/12/05 | $983,505 |
| RP130432 | Protein Array and Analysis Core (PAAC) | RES | Bedford, Mark T | The University of Texas M.D. Anderson Cancer Center | All Sites | 2012/12/05 | $1,940,486 |
| RP130455 | Virus Nanoparticles Programmed To Recognize and Treat Ovarian Carcinoma | RES | Suh, Junghae | Rice University | Ovary | 2012/12/05 | $199,999 |
| RP130459 | Cancer Communication Interventions to Increase HPV Vaccination among Hispanic Adolescents | RES | Fernandez, Maria E | The University of Texas Health Science Center at Houston | Cervix Uteri | 2012/12/05 | $1,496,029 |
| RP130464 | Requirement for Ascl1 in Gliomagenesis | RES | Johnson, Jane E | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2012/12/05 | $785,018 |
| RP130485 | Targeting Therapy Resistance using Epithelial to Mesenchymal Transition (EMT) Pathways in Preclinical Claudin Low Breast Cancer Models | RES | Rosen, Jeffrey M | Baylor College of Medicine | Breast | 2012/12/05 | $845,930 |
| RP130502 | Role of MicroRNA in Lung Cancer Risk & Clinical Outcome Prediction | RES | Wu, Xifeng | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2012/12/05 | $1,362,467 |
| RP130513 | Discovery and optimization of natural and artificial ligands regulating Hypoxia Inducible Factor | RES | Bruick, Richard | The University of Texas Southwestern Medical Center | All Sites | 2012/12/05 | $1,433,257 |
| RP130515 | Using microbial pathogens to probe weaknesses in human lung cancer | RES | Alto, Neal | The University of Texas Southwestern Medical Center | All Sites, Lung and Bronchus | 2012/12/05 | $199,472 |
| RP130516 | Clinical Application of Umbilical Cord Blood-Derived Designer T Cells | RES | Cooper, Laurence | The University of Texas M.D. Anderson Cancer Center | Leukemia, Lymphoma | 2012/12/05 | $1,262,675 |
| RP130533 | Establishing proteomic-level super-resolution imaging analyses of cancer stem cell phenotypes and behaviors | RES | Diehl, Michael R | Rice University | All Sites, Breast | 2012/12/05 | $200,000 |
| RP130547 | Pharmacokinetics and Pharmacogenomics of 13-cis-retinoic acid in treatment outcome of COG Phase III neuroblastoma trials | RES | Kang, Min H | Texas Tech University Health Sciences Center | Other | 2012/12/05 | $821,051 |
| RP130548 | Overcoming CXCL12 Mediated Resistance in Glioblastoma | RES | Brenner, Andrew J | The University of Texas Health Science Center at San Antonio | Brain and Other Nervous System | 2012/12/05 | $755,718 |
| RP130553 | Exploration of synergistic effects by using a combination of two novel antitumor agents and nano-delivery vehicle to effectively treat resistant solid tumors | RES | Zhang, Xiaoliu | University of Houston | Head and Neck, Lung and Bronchus, Ovary | 2012/12/05 | $1,215,651 |
| RP130570 | Single-Cell Biomarkers of Clinical-Grade T Cells and NK Cells to Optimize Tumor Immunotherapy | RES | Varadarajan, Navin | University of Houston | All Sites, Leukemia | 2012/12/05 | $1,279,584 |
| RP130573 | Blocking TNFR1 increases tumor radiosensitivity and ameliorates radiation-induced cognitive impairments | RES | Gaber, Mostafa W | Baylor College of Medicine | All Sites, Brain and Other Nervous System | 2012/12/05 | $1,357,896 |
| RP130588 | Targeting Tumor and Tumor-Supportive Stroma by NKT Cells | RES | Metelitsa, Leonid S | Baylor College of Medicine | Other | 2012/12/05 | $1,509,802 |
| RP130597 | Single organelle analysis for metabolites in tumor cells using microfluidic devices coupled to direct Nanoextraction-Nanospray | RES | Verbeck, Guido F | University of North Texas | All Sites, Colorectal | 2012/12/05 | $181,419 |
| RP130603 | Evaluation of the role of the BAP1 tumor suppressor gene in renal cancer | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2012/12/05 | $1,205,451 |
| RP130604 | Imaging cancer with radiofluorinated organoboron/biomolecule conjugates | RES | Gabbai, Francois | Texas A&M University | All Sites | 2012/12/05 | $199,997 |
| RP130607 | Role of Long Non-Coding RNAs in Breast Cancers: Identification, Characterization, and Determination of Molecular Functions | RES | Kraus, W. Lee | The University of Texas Southwestern Medical Center | Breast | 2012/12/05 | $846,522 |
| RP130624 | Diagnosis and Prognosis of Cancers through Glycomics and Glycoproteomics | RES | Mechref, Yehia | Texas Tech University | Breast | 2012/12/05 | $1,226,370 |
| RP130629 | Genotype and Metabolic Phenotype in Pediatric Brain Cancer (Carson Leslie Award) | RES | Maher, Elizabeth A | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2012/12/05 | $1,050,000 |
| RP130639 | A role for non-coding RNA in the regulation of telomerase in breast cancer | RES | Shippen, Dorothy E | Texas Agrilife Research | All Sites, Breast | 2012/12/05 | $199,912 |
| RP130651 | MAPK4 Activates AR and Promotes Castration-Resistant Prostate Cancer | RES | Yang, Feng | Baylor College of Medicine | Prostate | 2012/12/05 | $579,578 |
| RP130660 | Creating Novel Translation Inhibitors to Target Pro-survival Oncoproteins | RES | Romo, Daniel | Texas A&M University | All Sites, Leukemia | 2012/12/05 | $198,295 |
| RP130702 | Noninvasive skin cancer diagnosis using multi-modal spectroscopy | RES | Tunnell, James W | The University of Texas at Austin | Skin | 2012/12/05 | $1,242,101 |
| RP140001 | Role of DNA METHYLTRANSFERASE 3A in Hematologic Malignancies | RES | Goodell, Margaret A | Baylor College of Medicine | Breast, Leukemia, Lung and Bronchus, Lymphoma | 2014/08/20 | $900,000 |
| RP140020-AC | Administrative Core | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | 2014/02/19 | $203,428 | |
| RP140020-C1 | C1: Data Core | RES | Zhang, Dong D | The University of Texas Medical Branch at Galveston | 2014/02/19 | $551,286 | |
| RP140020-C2 | C2:Training Core | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | 2014/02/19 | $493,130 | |
| RP140020-C3 | C3:Knowledge Translation Core | RES | Eschbach, Karl | The University of Texas Medical Branch at Galveston | 2014/02/19 | $179,302 | |
| RP140020-P1 | P1:Evaluation of Cancer Screening Practices | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | 2014/02/19 | $337,836 | |
| RP140020-P2 | P2:Assessing the Quality of Cancer Treatment in Texas | RES | Giordano, Sharon | The University of Texas M.D. Anderson Cancer Center | 2014/02/19 | $581,550 | |
| RP140020-P3 | P3:Quality of Post-Treatment Surveillance of Cancer Patients in Texas | RES | Mehta, Hemalkumar | The University of Texas Medical Branch at Galveston | 2014/02/19 | $369,658 | |
| RP140020-P4 | P4:Quality of Supportive Cancer Care in Texas | RES | Elting, Linda | The University of Texas M.D. Anderson Cancer Center | 2014/02/19 | $514,858 | |
| RP140021-AC | Administrative Core | RES | Sherry, Dean | The University of Texas Southwestern Medical Center | 2014/02/19 | $61,775 | |
| RP140021-P2 | P2:Biomarkers and Metabolic Pathways in Gliomas | RES | Malloy, Craig | The University of Texas Southwestern Medical Center | 2014/02/19 | $427,069 | |
| RP140021-P3 | P3:Metobolic Imaging of Hyperpolarized 13C Substrates in Animal Models of Cancer | RES | DeBerardinis, Ralph J | The University of Texas Southwestern Medical Center | 2014/02/19 | $425,338 | |
| RP140021-P4 | P4:High Field MRS and CEST Imaging of Brain Tumors: Biomarkers of Therapeutic Response | RES | Choi, Changho | The University of Texas Southwestern Medical Center | 2014/02/19 | $528,558 | |
| RP140021-P5 | P5: Fast Imaging Methods for Hyperpolarized Nuclei | RES | Bankson, James | The University of Texas M.D. Anderson Cancer Center | 2014/02/19 | $316,148 | |
| RP140022-AC | Administrative Core | RES | Poplack, David | Baylor College of Medicine | 2014/02/19 | $173,764 | |
| RP140022-C2 | C2:Targeted Therapies for Metastatic Osteosarcoma | RES | Yustein, Jason | Baylor College of Medicine | 2014/02/19 | $233,510 | |
| RP140022-C3 | C3:Targeted Therapies for Metastatic Osteosarcoma | RES | Rao, Pulivarthi | Baylor College of Medicine | 2014/02/19 | $211,697 | |
| RP140022-C4 | C4:Targeted Therapies for Metastatic Osteosarcoma | RES | Hicks, John | Baylor College of Medicine | 2014/02/19 | $185,308 | |
| RP140022-P1 | P1:Targeted Therapies for Metastatic Osteosarcoma | RES | Donehower, Lawrence | Baylor College of Medicine | 2014/02/19 | $413,445 | |
| RP140022-P2 | P2:Targeted Therapies for Metastatic Osteosarcoma | RES | Lau, Ching | Baylor College of Medicine | 2014/02/19 | $621,372 | |
| RP140022-P3 | P3:Targeted Therapies for Metastatic Osteosarcoma | RES | Gottschalk, Stephen | Baylor College of Medicine | 2014/02/19 | $381,376 | |
| RP140024-AC | Administrative Core | RES | McDevitt, John | Rice University | 2014/02/19 | $247,736 | |
| RP140024-C1 | C1:Texas Cancer Diagnostics Pipeline Consortium | RES | Vigneswaran, Nadarajah | The University of Texas Health Science Center at Houston | 2014/02/19 | $368,368 | |
| RP140024-C2 | C2:Texas Cancer Diagnostics Pipeline Consortium | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | 2014/02/19 | $484,611 | |
| RP140024-C3 | C3:Texas Cancer Diagnostics Pipeline Consortium | RES | Yeh, Chih-Ko | The University of Texas Health Science Center at San Antonio | 2014/02/19 | $411,928 | |
| RP140024-P1 | P1:Texas Cancer Diagnostics Pipeline Consortium | RES | McDevitt, John | Rice University | 2014/02/19 | $1,823,582 | |
| RP140024-P2 | P2:Texas Cancer Diagnostics Pipeline Consortium | RES | Thompson, Ian M | The University of Texas Health Science Center at San Antonio | 2014/02/19 | $576,000 | |
| RP140102 | Baylor College of Medicine Comprehensive Cancer Training Program | RES | Rosen, Jeffrey M | Baylor College of Medicine | Multiple Sites | 2014/02/19 | $1,574,628 |
| RP140103 | Collaborative Training of a New Cadre of Innovative Cancer Prevention Researchers | RES | Ness, Roberta | The University of Texas Health Science Center at Houston | Multiple Sites | 2014/02/19 | $1,745,076 |
| RP140105 | Cancer Research Training Grant | RES | Oyajobi, Babatunde | The University of Texas Health Science Center at San Antonio | Multiple Sites | 2014/02/19 | $1,588,673 |
| RP140106 | The Future of Cancer Research: Training Program for Basic and Translational Scientists | RES | Watowich, Stephanie | The University of Texas M.D. Anderson Cancer Center | Multiple Sites | 2014/02/19 | $1,710,524 |
| RP140108 | Molecularly-Targeted Approaches to Cancer Therapeutics, Diagnostics and Prevention | RES | Sessler, Jonathan | The University of Texas at Austin | Multiple Sites | 2014/02/19 | $1,648,814 |
| RP140110 | Cancer Intervention and Prevention Discoveries Program | RES | White, Michael | The University of Texas Southwestern Medical Center | 2014/02/19 | $1,916,038 | |
| RP140113 | Continuation of Computational Cancer Biomedicine Training Program | RES | Briggs, James | University of Houston | 2014/02/19 | $1,591,594 | |
| RP140132 | Towards Point-of-Care Nucleic Acid Cancer Diagnostics | RES | Zhang, David | Rice University | All Sites | 2014/08/20 | $900,000 |
| RP140140 | Turn on the Tumor Contrast for Surgical Resection of Head and Neck Cancers | RES | Gao, Jinming | The University of Texas Southwestern Medical Center | Head and Neck | 2014/08/20 | $900,000 |
| RP140141 | Targeting HER2 for Cancer Therapy | RES | Ward, Elizabeth S | Texas A&M University System Health Science Center | Bladder, Breast, Lung and Bronchus, Ovary, Pancreas, Prostate | 2014/08/20 | $892,989 |
| RP140143 | Dependence of Small Cell Lung Cancer on the Basic Helix- Loop-Helix Transcription Factors Ascl1 and NeuroD1 | RES | Cobb, Melanie H | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2014/08/20 | $900,000 |
| RP140152 | Natural Product for Treatment of Non Small Cell Lung Cancer | RES | MacMillan, John | The University of Texas Southwestern Medical Center | Breast, Lung and Bronchus | 2014/08/20 | $772,368 |
| RP140179 | Targeting Self-Renewal in Leukemic Stem Cells Through the Inactivation of KLF4 | RES | Lacorazza, Daniel | Baylor College of Medicine | Leukemia | 2014/08/20 | $813,789 |
| RP140181 | Mechanisms of CTC Biomarkers in Breast Cancer Brain Metastasis | RES | Marchetti, Dario | The Methodist Hospital Research Institute Prev. Org: Baylor College of Medicine Expended at Prev. Org: $278,638.49 | Brain and Other Nervous System, Breast | 2014/08/20 | $621,329.51 |
| RP140216 | Context-Specific In Vivo Screening for KRAS-Associated Gene Aberration Drivers Using Genetically Engineered Mouse Models of Lung Cancer | RES | Scott, Kenneth L | Baylor College of Medicine | Lung and Bronchus | 2014/08/20 | $199,715 |
| RP140218 | Inhibiting Oxidative Phosphorylation: A Novel Strategy in Leukemia | RES | Konopleva, Marina | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2014/08/20 | $826,744 |
| RP140222 | Direct Roles for RB and E2F1 in DNA Repair | RES | Johnson, David | The University of Texas M.D. Anderson Cancer Center | All Sites | 2014/08/20 | $900,000 |
| RP140223 | Viral MicroRNAs in Ovarian Cancer Growth and Metastasis | RES | Anderson, Matthew L | Baylor College of Medicine | Ovary | 2014/08/20 | $199,995 |
| RP140224 | PPAR-Delta Regulation of Wnt/B-Catenin To Drive Colon Cancer | RES | Shureiqi, Imad | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2014/08/20 | $890,003 |
| RP140233 | Structure-Guided Kinase Inhibitor Design for Cancer Therapy | RES | Westover, Kenneth | The University of Texas Southwestern Medical Center | All Sites | 2014/08/20 | $900,000 |
| RP140244 | Regulation of MDM2-Mediated Oncogenesis and Anti-Tumor Immunity by USP15 | RES | Sun, Shao-Cong | The University of Texas M.D. Anderson Cancer Center | All Sites | 2014/08/20 | $870,156 |
| RP140252 | Investigating and Preclinical Targeting Molecular Drivers of Muscle-Invasive Bladder Cancer | RES | Chan, Keith | Baylor College of Medicine | Bladder | 2014/08/20 | $827,451 |
| RP140258 | The Intersection Between Childhood Cancer and Congenital Anomalies: Identifying Novel Cancer Predisposition Syndromes | RES | Lupo, Philip | Baylor College of Medicine | Childhood and Adolescent | 2014/08/20 | $874,964 |
| RP140262 | Intrinsic Reward Sensitivity & Smoking Cessation with Varenicline or Patch NRT | RES | Cinciripini, Paul M | The University of Texas M.D. Anderson Cancer Center | Bladder, Cervix Uteri, Head and Neck, Leukemia, Lung and Bronchus, Pancreas | 2014/08/20 | $899,505 |
| RP140271 | Targeting p53 in Cancer Through Manipulation of p63 and p73 | RES | Lee, Min Gyu | The University of Texas M.D. Anderson Cancer Center | All Sites | 2014/08/20 | $900,000 |
| RP140285 | Noninvasive Identification of Prostate Tumor Hypoxia as a Prognostic Biomarker of Radiation Response | RES | Mason, Ralph P | The University of Texas Southwestern Medical Center | Prostate | 2014/08/20 | $895,820 |
| RP140298 | Engineering Microfluidic Devices for Multimodal Mechanical Phenotyping of Tumor Cells in Flow | RES | Vanapalli, Siva | Texas Tech University | All Sites | 2014/08/20 | $674,465 |
| RP140315 | Accurate and High Throughput Detection of Breast and Ovarian Cancer Cells in Whole Blood | RES | Zu, Youli | The Methodist Hospital Research Institute | Breast, Ovary | 2014/08/20 | $900,000 |
| RP140320 | Dissecting a Necrotic Signaling Pathway in Human Cancer Cells | RES | Zhong, Qing | The University of Texas Southwestern Medical Center | Breast, Ovary, Pancreas, Prostate | 2014/08/20 | $200,000 |
| RP140323 | Role of a Novel Histone Variant-Specific Epigenetic Reader ZMYND11 in Breast Cancer | RES | Shi, Xiaobing | The University of Texas M.D. Anderson Cancer Center | Breast | 2014/08/20 | $899,534 |
| RP140328 | Synthetic Protein Degradation Agents To Clear Oncogenic Proteins From Cells | RES | Matouschek, Andreas | The University of Texas at Austin | All Sites | 2014/08/20 | $199,852 |
| RP140329 | Opening the Central Nervous System to Immunotherapy by Blocking TREK1 | RES | Curran, Michael | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2014/08/20 | $198,957 |
| RP140350 | Integrated Human Herpesvirus 6 as a Novel Heritable Risk Factor for Glioma | RES | Scheurer, Michael | Baylor College of Medicine | Brain and Other Nervous System | 2014/08/20 | $199,298 |
| RP140367 | Targeting BRD4 in Breast Cancer | RES | Chiang, Cheng-Ming | The University of Texas Southwestern Medical Center | Breast | 2014/08/20 | $900,000 |
| RP140399 | Targeting Hypoxia in Breast Cancer With Highly Potent Small- Molecule Anticancer Prodrugs | RES | Pinney, Kevin G | Baylor University | Breast | 2014/08/20 | $900,000 |
| RP140402 | Novel Targets for Acute Myeloid Leukemia Treatment | RES | Zhang, Chengcheng | The University of Texas Southwestern Medical Center | Leukemia | 2014/08/20 | $900,000 |
| RP140408 | Identification of a Novel Mechanism of mTORC1 and Autophagy Regulation for Cancer Therapy | RES | Sarbassov, Dos | The University of Texas M.D. Anderson Cancer Center | Breast | 2014/08/20 | $900,000 |
| RP140411 | Targeting Tumor Cell Invasion in Glioblastoma | RES | McCarty, Joseph | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2014/08/20 | $900,000 |
| RP140412 | Endotrophin and the Obesity/Cancer Nexus: Role in Growth and Chemoresistance | RES | Scherer, Philipp | The University of Texas Southwestern Medical Center | Breast | 2014/08/20 | $899,997 |
| RP140429 | The Role of DIRAS3 (ARHI) in Initiating Autophagy and Tumor Dormancy | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | Ovary | 2014/08/20 | $900,000 |
| RP140430 | Synaptic Mechanisms of Cognitive Decline After Cranial Radiation | RES | Grosshans, David | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System, Childhood and Adolescent | 2014/08/20 | $836,557 |
| RP140435 | SHH/GLI3 Signaling Axis as a Therapeutic Target in Castration Resistant Prostate Cancer | RES | Boyer, Thomas | The University of Texas Health Science Center at San Antonio | Prostate | 2014/08/20 | $200,000 |
| RP140449 | A New Cancer Target: AMPylation Machinery | RES | Orth, Kim | The University of Texas Southwestern Medical Center | All Sites | 2014/08/20 | $200,000 |
| RP140452 | Inactivating Mutation of D2HGDH Establishes a Novel Link Between Metabolism, Alpha-KG Dependent Dioxygenases and Epigenetic Reprograming in B Cell Lymphoma | RES | Aguiar, Ricardo | The University of Texas Health Science Center at San Antonio | Lymphoma | 2014/08/20 | $854,740 |
| RP140456 | Role of DNA2 Nuclease in Cellular Tolerance of Replication Stress and Telomere Maintenance - Implications for Cancer Biology and Anticancer Therapy | RES | Ira, Grzegorz | Baylor College of Medicine | All Sites | 2014/08/20 | $746,531 |
| RP140462 | Systematic Investigation of Clinically Relevant Expressed Pseudogenes in Cancer | RES | Liang, Han | The University of Texas M.D. Anderson Cancer Center | All Sites | 2014/08/20 | $870,539 |
| RP140464 | Next Generation Sequencing and Transcriptome Profiling of Oral Potentially Malignant Lesions To Identify Markers of Cancer Risk and Targets for Chemoprevention | RES | Zhang, Jianjun | The University of Texas M.D. Anderson Cancer Center | Head and Neck | 2014/08/20 | $900,000 |
| RP140468 | Targeting of Chronic Lymphocytic Leukemia by Designer T Cells | RES | Kebriaei, Partow | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2014/08/20 | $900,000 |
| RP140469 | Novel Small Molecule Probes Targeting IDH Mutated Glioma | RES | Song, Yongcheng | Baylor College of Medicine | Brain and Other Nervous System | 2014/08/20 | $695,527 |
| RP140473 | Investigation of the Tumor Suppressor TMEM127 on Lysosome Function and Lipid Metabolism | RES | Dahia, Patricia L | The University of Texas Health Science Center at San Antonio | All Sites | 2014/08/20 | $881,146 |
| RP140478 | Computational Chemistry Determination of DNA Damage Mechanisms in Proton Cancer Therapy To Optimize Its Clinical Use | RES | Morales, Jorge | Texas Tech University | Breast, Head and Neck, Lung and Bronchus, Prostate, Sarcoma | 2014/08/20 | $200,000 |
| RP140479 | Screening for Melanoma Genes Using Natural Hybrid Incompatibilities | RES | Rosenthal, Gil | Texas A&M University | Melanoma | 2014/08/20 | $199,993 |
| RP140482 | Preclinical Intravital Microscopy of Prostate Cancer Lesions in Bone: Identification and Eradication of Survival Niches by Combination Therapy | RES | Dondossola, Eleonora | The University of Texas M.D. Anderson Cancer Center | Prostate | 2014/08/20 | $256,061 |
| RP140500 | Toward the Cure of Myelodysplastic Syndrome: Interfering With Innate Immunity Alterations in Human and Mouse Systems | RES | Garcia-Manero, Guillermo | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2014/08/20 | $900,000 |
| RP140515 | CDK Inhibitors as Adjunctive to 5-FU and/or Radiation in Esophageal Adenocarcinoma- Assessment of Efficacy and Predictive Biomarkers | RES | Maru, Dipen | The University of Texas M.D. Anderson Cancer Center | Head and Neck | 2014/08/20 | $882,133 |
| RP140517 | Optimal Biomarkers for Personalized Cancer Therapy: A Network-Based Approach | RES | Vidyasagar, Mathukumalli | The University of Texas at Dallas | Breast, Lung and Bronchus, Ovary | 2014/08/20 | $490,689 |
| RP140522 | Reversing Vaccination-Induced Impairment of Anti-CTLA-4- Based Cancer Therapy | RES | Overwijk, Willem | The University of Texas M.D. Anderson Cancer Center | Melanoma | 2014/08/20 | $899,991 |
| RP140542 | Biology and Therapy of Basal Bladder Cancers | RES | Dinney, Colin | The University of Texas M.D. Anderson Cancer Center | Bladder | 2014/08/20 | $865,587 |
| RP140544 | Mapping Acidic Tumor Microenvironment With Renal Clearable pH Nanoindicators | RES | Zheng, Jie | The University of Texas at Dallas | All Sites | 2014/08/20 | $900,000 |
| RP140553 | Translational Discovery of Resistance Genes and Cancer Gene Functions | RES | Rosenberg, Susan | Baylor College of Medicine | Breast, Colorectal, Head and Neck, Lung and Bronchus, Pancreas, Stomach | 2014/08/20 | $900,000 |
| RP140556 | DNA Methylation and Telomere Length in Peripheral Blood as Predictors of Aggressive Prostate Cancer | RES | Gu, Jian | The University of Texas M.D. Anderson Cancer Center | Prostate | 2014/08/20 | $898,721 |
| RP140563 | PAF, a Novel Wnt Signaling Regulator, in Colorectal Cancer | RES | Park, Jae-Il | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2014/08/20 | $900,000 |
| RP140594 | microRNAs: Safe and Effective Therapeutic Adjuvants for Treating Drug Resistant Breast Cancers | RES | Rao, Manjeet | The University of Texas Health Science Center at San Antonio | Breast | 2014/08/20 | $900,000 |
| RP140606 | Optimizing Therapy for Glioblastoma Through Genomic Profiling of Treatment Failure | RES | de Groot, John | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2014/08/20 | $900,000 |
| RP140609 | A Missing Link Between Obesity and Cancer: Adipose Derived Stem Cells | RES | Klopp, Ann | The University of Texas M.D. Anderson Cancer Center | Ovary | 2014/08/20 | $610,704 |
| RP140612 | Collateral Genomic Deletions as Targetable Vulnerabilities in Cancer | RES | DePinho, Ronald | The University of Texas M.D. Anderson Cancer Center | All Sites | 2014/08/20 | $900,000 |
| RP140616 | Tenascin-C and Metastatic Prostate Cancer Progression | RES | Rowley, David | Baylor College of Medicine | Prostate | 2014/08/20 | $827,806 |
| RP140648 | New Therapeutic Strategies for Metastatic Melanoma | RES | Dalby, Kevin N | The University of Texas at Austin | Melanoma | 2014/08/20 | $900,000 |
| RP140649 | Realizing Personalized and Precision Medicine for Melanoma: A Rapid Assay for Measuring ERK Activity | RES | Dalby, Kevin N | The University of Texas at Austin | Melanoma | 2014/08/20 | $200,000 |
| RP140655 | Evaluation of the Role of Tumor Suppressor Candidate NPRL2 in Cell Growth Control | RES | Tu, Benjamin P | The University of Texas Southwestern Medical Center | All Sites | 2014/08/20 | $596,265 |
| RP140661 | Analyses of the Regulatory Mechanisms of Tankyrase and Its Role in Tumorigenesis | RES | Zhang, Xuewu | The University of Texas Southwestern Medical Center | Colorectal, Lung and Bronchus, Prostate | 2014/08/20 | $876,751 |
| RP140664 | Development of Therapeutic Antibodies Having Both Fc[gamma] and Fc[Alpha] Effector Functions and Displaying Potent Cancer Cell Killing | RES | Georgiou, George | The University of Texas at Austin | Breast, Colorectal | 2014/08/20 | $200,000 |
| RP140672 | Mutant KRAS Reprograms Lipid Metabolism Exposing Beta- Oxidation as a Novel Therapeutic Target in Lung Cancer | RES | Minna, John | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2014/08/20 | $687,759 |
| RP140678 | Novel, Humanized Single-Chain CD123xCD3 Bispecific Antibodies for Eliminating Leukemia Stem Cells and Leukemic Cells | RES | Woo, Jung H | Scott and White Healthcare | Leukemia | 2014/08/20 | $199,959 |
| RP140685 | Modulation of Autophagy: Phase II Study of Vorinostat Plus Hydroxychloroquine vs. Regorafenib in Refractory Metastatic Colorectal Cancer (mCRC) | RES | Arora, Sukeshi | The University of Texas Health Science Center at San Antonio | Colorectal | 2014/08/20 | $825,285 |
| RP140767 | Toll-Like Receptors, Gut Microbiota, and Risk of Colorectal Adenoma | RES | Jiao, Li | Baylor College of Medicine | Colorectal | 2014/08/20 | $899,131 |
| RP140781 | High-Field Open MRI: Cost-Effective Screening for Early Detection of Breast Cancer | RES | McIntyre, Peter | Texas A&M Engineering Experiment Station Prev. Org: Texas A&M University Expended at Prev. Org: $15,892.30 | Brain and Other Nervous System, Breast, Cervix Uteri, Colorectal, Gallbladder, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct, Lung and Bronchus, Ovary, Pancreas, Prostate, Small Intestine | 2014/08/20 | $184,107.70 |
| RP140784 | Next Generation Sequencing-Based Approaches for the Development of Epigenetic Biomarkers for Predicting Therapeutic Outcome in Patients With Colorectal Cancer | RES | Goel, Ajay | Baylor College of Medicine | Colorectal | 2014/08/20 | $886,982 |
| RP140800 | The Role of Alternative Polyadenylation in Glioblastoma Tumor Progression | RES | Wagner, Eric J | The University of Texas Medical Branch at Galveston Prev. Org: The University of Texas Health Science Center at Houston Expended at Prev. Org: $123,718.72 | Brain and Other Nervous System | 2014/08/20 | $724,772.28 |
| RP140840 | New Technology for Ultra High Throughput Enumeration of Circulating Tumor Cells | RES | Vanapalli, Siva | Texas Tech University | All Sites | 2014/08/20 | $199,993 |
| RP140842 | Determining the Functional Role of microRNAs in Viral Tumorigenesis | RES | Sullivan, Christopher S | The University of Texas at Austin | Cervix Uteri, Head and Neck, Leukemia, Lymphoma, Sarcoma, Skin | 2014/08/20 | $604,624 |
| RP150006 | Defining and Treating Targetable Lesions in AYA Acute Lymphoblastic Leukemia | RES | Konopleva, Marina | The University of Texas M.D. Anderson Cancer Center | Childhood and Adolescent, Leukemia | 2015/02/18 | $1,989,950 |
| RP150014 | Multi-component interventions for patients and providers to increase HPV vaccination in a network of pediatric clinics in Houston, TX | RES | Vernon, Sally | The University of Texas Health Science Center at Houston | Cervix Uteri, Head and Neck, Penis, Vagina, Vulva | 2015/02/18 | $1,527,379 |
| RP150030 | Exploring molecular and immune mechanisms of response and resistance to combined BRAF/MEK inhibition in patients with high-risk resectable metastatic melanoma | RES | Wargo, Jennifer | The University of Texas M.D. Anderson Cancer Center | Melanoma | 2015/02/18 | $900,000 |
| RP150032 | Developing New Combinatory Therapies for Pediatric High Grade Glioma | RES | Li, Xiao-Nan | Baylor College of Medicine | Brain and Other Nervous System | 2015/02/18 | $1,945,940 |
| RP150053 | Mechanisms of nuclear import and export in cancer | RES | Chook, Yuh Min | The University of Texas Southwestern Medical Center | All Sites | 2015/02/18 | $745,064 |
| RP150079 | Elucidating the evolution of the premalignant airway genome in space and time | RES | Kadara, Humam | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2015/02/18 | $886,173 |
| RP150081 | Genetic susceptibility to testicular germ cell tumors | RES | Heaney, Jason | Baylor College of Medicine | Testis | 2015/02/18 | $1,406,791 |
| RP150084 | Role of PTEN feedback mechanism in cancer | RES | Song, Min Sup | The University of Texas M.D. Anderson Cancer Center | Breast, Prostate, Thyroid | 2015/02/18 | $900,000 |
| RP150093 | Targeting 17q23 amplicon in HER2-positive Breast Cancer | RES | Zhang, Xinna | The University of Texas M.D. Anderson Cancer Center | Breast | 2015/02/18 | $828,242 |
| RP150094 | Investigating the regulation of miRNA and lncRNAs by p63 in mammary tumor progression and metastasis | RES | Lin, Chunru | The University of Texas M.D. Anderson Cancer Center | Breast | 2015/02/18 | $900,000 |
| RP150102 | Genome stability and immune diversity controlled by the POLQ pathway | RES | McBride, Kevin | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/02/18 | $900,000 |
| RP150129 | Drug Discovery and Mechanistic Studies of Protein Methylation Targeting Leukemia | RES | Song, Yongcheng | Baylor College of Medicine | Childhood and Adolescent, Leukemia | 2015/02/18 | $1,733,813 |
| RP150148 | Identifying Drivers of Lung Metastasis in Triple Negative Breast Cancer | RES | Piwnica-Worms, Helen | The University of Texas M.D. Anderson Cancer Center | Breast | 2015/02/18 | $899,637 |
| RP150164 | Using imaging and computational tools to improve risk stratification in children with bone cancer | RES | Leavey, Patrick | The University of Texas Southwestern Medical Center | Bone, Childhood and Adolescent, Sarcoma | 2015/02/18 | $1,290,442 |
| RP150166 | Prostate Cancer Chemoprevention with Resveratrol | RES | Kumar, Addanki | The University of Texas Health Science Center at San Antonio | Prostate | 2015/02/18 | $900,000 |
| RP150179 | Regulation of dormancy of metastatic prostate cancer cells by bone microenvironment | RES | Lin, Sue-Hwa | The University of Texas M.D. Anderson Cancer Center | Bone, Prostate | 2015/02/18 | $900,000 |
| RP150195 | Mechanisms of DHA and EPA differential effects on colon cancer chemoprevention | RES | Shureiqi, Imad | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2015/02/18 | $920,926 |
| RP150197 | Understanding How NCOA6 Suppresses Endometrial Cancer by Inhibiting the Wnt/beta-Catenin Pathway | RES | Xu, Jianming | Baylor College of Medicine | Cervix Uteri | 2015/02/18 | $886,524 |
| RP150224 | Discovering the molecular mechanisms that determine replicative lifespan | RES | Tyler, Jessica | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/02/18 | $892,104 |
| RP150228 | Varenicline and Combined NRT for Initial Smoking Cessation and Rescue Treatment in Smokers: A Randomized Pilot Trial | RES | Cinciripini, Paul M | The University of Texas M.D. Anderson Cancer Center | Bladder, Head and Neck, Lung and Bronchus, Myeloma, Ovary, Pancreas | 2015/02/18 | $1,493,464 |
| RP150230 | Counteracting tumor evasion of antibody immunity by a novel therapeutic strategy | RES | An, Zhiqiang | The University of Texas Health Science Center at Houston | All Sites | 2015/02/18 | $900,000 |
| RP150231 | Function of Fibroblasts and Collagen I in Pancreas Cancer | RES | Kalluri, Raghu | The University of Texas M.D. Anderson Cancer Center | Pancreas | 2015/02/18 | $898,811 |
| RP150232 | The Role of Progesterone Receptor in Early Stage Breast Cancer. | RES | Edwards, Dean P | Baylor College of Medicine | Breast | 2015/02/18 | $864,661 |
| RP150235 | Role of TBK1 in Regulating Dendritic Cell Function and Antitumor Immunity. | RES | Sun, Shao-Cong | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/02/18 | $876,958 |
| RP150242 | Functional and structural characterization of a small chemical compound that arrests glioma stem cell growth with high activity and specificity | RES | De Brabander, Jef K | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2015/02/18 | $900,000 |
| RP150245 | EGFR Arginine Methylations: Biomarkers for Cetuximab Resistance in colon cancer | RES | Hung, Mien-Chie | The University of Texas M.D. Anderson Cancer Center | Colorectal | 2015/02/18 | $900,000 |
| RP150277 | Vertical targeting of the B cell receptor in leukemia and lymphoma | RES | Aguiar, Ricardo | The University of Texas Health Science Center at San Antonio | Leukemia, Lymphoma | 2015/02/18 | $899,879 |
| RP150282 | Mechanisms of de novo and acquired resistance to therapeutic treatment of bone-metastatic prostate cancer | RES | Gallick, Gary | The University of Texas M.D. Anderson Cancer Center | Prostate | 2015/02/18 | $900,000 |
| RP150292 | Broad Shortening of 3’ UTRs in Human Cancers: Methods, Target Genes and Functional Consequences | RES | Li, Wei | Baylor College of Medicine | All Sites | 2015/02/18 | $900,000 |
| RP150293 | Identification of clinically relevant targets for radiosensitization | RES | Skinner, Heath | The University of Texas M.D. Anderson Cancer Center | Head and Neck | 2015/02/18 | $899,280 |
| RP150301 | Epigenetics in Medulloblastoma Development and Therapeutics | RES | Gopalakrishnan, Vidya | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System, Childhood and Adolescent | 2015/02/18 | $1,871,708 |
| RP150316 | T-cell activating immunotherapy for indolent B-cell malignancies | RES | Neelapu, Sattva | The University of Texas M.D. Anderson Cancer Center | Lymphoma | 2015/02/18 | $852,595 |
| RP150319 | Leukemia inhibitory factor receptor signaling and function in cancer | RES | Ma, Li | The University of Texas M.D. Anderson Cancer Center | Breast, Gallbladder, Liver and Intrahepatic Bile Duct | 2015/02/18 | $900,000 |
| RP150334 | Personalized Functionalization of Pediatric High Grade Glioma | RES | Deneen, Benjamin | Baylor College of Medicine | Brain and Other Nervous System | 2015/02/18 | $1,820,319 |
| RP150343 | An ultra-sensitive nanomagnetic sensor for the early detection of anaplastic large cell lymphoma | RES | Willson, Richard C | University of Houston | Childhood and Adolescent, Lymphoma | 2015/02/18 | $1,929,710 |
| RP150346 | Targeting Twist1 for Prevention and Treatment of Non-Melanoma Skin Cancer | RES | DiGiovanni, John | The University of Texas at Austin | Skin | 2015/02/18 | $900,000 |
| RP150356 | Peripheral nerve tolerance to single-session stereotactic irradiation | RES | Medin, Paul | The University of Texas Southwestern Medical Center | All Sites | 2015/02/18 | $897,779 |
| RP150386 | A Phase I Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer | RES | Phan, Jack | The University of Texas M.D. Anderson Cancer Center Prev. Org: The University of Texas Southwestern Medical Center Expended at Prev. Org: $198,153.19 | Head and Neck | 2015/02/18 | $662,386.81 |
| RP150403 | On the role of DEAR1 in the regulation of cell polarity and progression from DCIS to invasive breast cancer | RES | Killary, Ann | The University of Texas M.D. Anderson Cancer Center | Breast | 2015/02/18 | $899,846 |
| RP150405 | Tumor Cell Epithelial-Mesenchymal Transition in Regulating Immunosuppression and Metastasis in Lung Cancer | RES | Gibbons, Don | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2015/02/18 | $900,000 |
| RP150408 | Cellular mechanisms of chemotherapy-induced peripheral neuropathy | RES | Stockand, James | The University of Texas Health Science Center at San Antonio | All Sites | 2015/02/18 | $593,532 |
| RP150416 | Translational Investigations On Fenretinide and Safingol For Pediatric Cancer Use | RES | Maurer, Barry J | Texas Tech University Health Sciences Center | Childhood and Adolescent | 2015/02/18 | $1,999,415 |
| RP150421 | High-throughput Screening and Detection of Circulating Tumor Cells | RES | Ugaz, Victor | Texas A&M Engineering Experiment Station | Breast, Prostate | 2015/02/18 | $1,135,450 |
| RP150440 | Effects of hormonal therapy on subclonal evolution of breast tumors with ESR1 mutations | RES | Fuqua, Suzanne A | Baylor College of Medicine | Breast | 2015/02/18 | $899,805 |
| RP150445 | Ewing’s sarcoma, a homologous recombination defective disease | RES | Bishop, Alexander | The University of Texas Health Science Center at San Antonio | Childhood and Adolescent | 2015/02/18 | $1,979,137 |
| RP150449 | Noninvasive multiscale imaging for optical biopsy in epithelial cancers | RES | Vargas, Gracie | The University of Texas Medical Branch at Galveston | Head and Neck | 2015/02/18 | $852,748 |
| RP150451 | SRC-2 driven “Metabolic Switch” in metastatic prostate cancer- Prognostic and Therapeutic implications | RES | Sreekumar, Arun | Baylor College of Medicine | Prostate | 2015/02/18 | $633,710 |
| RP150454 | Tumor Suppression Through the cGAMP/STING Pathway | RES | Li, Pingwei | Texas Agrilife Research | All Sites | 2015/02/18 | $900,000 |
| RP150456 | TAMU–UT Southwestern Partnership for Breast Imaging and Spectroscopy at 7 Tesla | RES | Malloy, Craig | The University of Texas Southwestern Medical Center | Breast | 2015/02/18 | $897,311 |
| RP150485 | Translating Online Adaptive Radiotherapy from Lab to Clinical Practice | RES | Jiang, Steve | The University of Texas Southwestern Medical Center | All Sites | 2015/02/18 | $858,356 |
| RP150498 | Harnessing the Cytosolic DNA Sensing Pathway for Cancer Immunotherapy | RES | Chen, Zhijian J | The University of Texas Southwestern Medical Center | Lung and Bronchus, Melanoma, Pancreas | 2015/02/18 | $889,185 |
| RP150535 | Precision Oncology Decision Support Core | RES | Meric-Bernstam , Funda | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/05/20 | $5,999,996* |
| RP150551 | Therapeutic Monoclonal Antibody Lead Optimization and Development Core | RES | An, Zhiqiang | The University of Texas Health Science Center at Houston | All Sites | 2015/05/20 | $5,277,338 |
| RP150559 | Small Molecules to Perturb A Novel PPI Target For Chemotherapy | RES | Burgess, Kevin | Texas A&M University | Leukemia | 2015/05/20 | $200,000* |
| RP150573 | Dynamin GTPase: A novel pro-apoptotic cancer therapeutic target | RES | Schmid , Sandra | The University of Texas Southwestern Medical Center | All Sites | 2015/05/20 | $200,000 |
| RP150574 | Turning on a Novel Tumor-Inhibiting Switch for Colorectal Cancer | RES | Li, Rong | The University of Texas Health Science Center at San Antonio | Colorectal | 2015/05/20 | $200,000 |
| RP150578 | The Combinatorial Drug Discovery Program (CDDP) | RES | Davies, Peter | Texas A&M University System Health Science Center | All Sites | 2015/05/20 | $5,954,596 |
| RP150587 | The Texas Hepatocellular Carcinoma Consortium (THCCC) | RES | El-Serag, Hashem | Baylor College of Medicine | Gallbladder, Liver and Intrahepatic Bile Duct | 2015/05/20 | $9,771,157 |
| RP150590 | Identifying Inhibitors of Ascl1 to Block Growth of Malignant Neuroendocrine and Neural Tumors | RES | Johnson, Jane E | The University of Texas Southwestern Medical Center | Brain and Other Nervous System, Lung and Bronchus | 2015/05/20 | $200,000 |
| RP150596 | Bioinformatics Core Facility at UT Southwestern Medical Center | RES | Danuser, Gaudenz | The University of Texas Southwestern Medical Center | All Sites | 2015/05/20 | $5,593,882 |
| RP150600 | The Single-Cell Biopsy and Characterization Core (SBCC) at The University of Texas Health Science at San Antonio | RES | Huang, Tim | The University of Texas Health Science Center at San Antonio | All Sites | 2015/05/20 | $3,277,895 |
| RP150611 | CPRIT Core for RNA Therapeutics and Research | RES | Cooke, John | The Methodist Hospital Research Institute | All Sites | 2015/05/20 | $4,845,868 |
| RP150632 | Acetate may be a key substrate driving growth in early stage breast cancer in patients | RES | Bachoo, Robert | The University of Texas Southwestern Medical Center | Breast | 2015/05/20 | $200,000 |
| RP150637 | Efficient Production of iPSC-Derived Mesenchymal Stem Cells to Kill Cancers by Bystander Effects from Suicide Genes | RES | Bartosh, Thomas | Texas A&M University System Health Science Center | All Sites | 2015/05/20 | $200,000* |
| RP150638 | Elevated D-2-hydroxyglutarate precedes and promotes tumor progression in inflammatory bowel diseases | RES | Theiss, Arianne | Baylor Research Institute | Colorectal | 2015/05/20 | $200,000 |
| RP150640 | Drug Conjugates of anti-LGR5 Antibodies as Novel Therapeutics for Destroying Cancer Stem Cells | RES | Carmon, Kendra | The University of Texas Health Science Center at Houston | Colorectal, Gallbladder, Liver and Intrahepatic Bile Duct, Ovary, Small Intestine | 2015/05/20 | $200,000 |
| RP150648 | GATA2 and steroid receptor coactivator-2 cooperate with androgen receptor in prostate cancer progression and androgen resistance | RES | O'Malley, Bert | Baylor College of Medicine | Prostate | 2015/05/20 | $6,151,179 |
| RP150656 | Engineered Bone Targeting Nanomedicine for Treatment of Bone Metastases from Breast Cancer | RES | Liu, Xinli | University of Houston Prev. Org: Texas Tech University Health Sciences Center Expended at Prev. Org: $77,599.30 | Bone, Breast | 2015/05/20 | $122,370.70 |
| RP150676 | Identification of Novel Melanoma Metastasis Driver Genes through Transposon-Mediated Mutagenesis | RES | O'Donnell, Kathryn | The University of Texas Southwestern Medical Center | Melanoma | 2015/05/20 | $200,000 |
| RP150696 | Inhibition of Breast Cancer Metastasis to the Bone by microRNA Transmission through Gap Junctions | RES | Nicholson, Bruce | The University of Texas Health Science Center at San Antonio | Bone, Breast | 2015/05/20 | $200,000 |
| RP150701 | Non-invasive Colonoscopy by Molecular Imaging of Mucin Targeted Hyperpolarized Silicon Nanoparticles | RES | Carson, Daniel D | Rice University | Colorectal | 2015/05/20 | $200,000 |
| RP150703 | Metabolomic Salivary Biomarkers for Oral Cancer Detection | RES | Cheng, Yi-Shing | Texas A&M University System Health Science Center | Head and Neck | 2015/05/20 | $199,999 |
| RP150711 | Biomechanical profiling of migrating brain cancer genotypes in tightly-confined space for drug screening | RES | Kim, Young-tae | The University of Texas at Arlington | Brain and Other Nervous System | 2015/05/20 | $199,998 |
| RP150713 | Identification of Therapeutic Targets on Breast Cancer Stem Cells | RES | Lee, Jiyong | The University of Texas at Dallas | Breast | 2015/05/20 | $194,543 |
| RP150720 | Integrated on-chip networks for investigating exosome-mediated drug expulsion | RES | Li, Wei | Texas Tech University | All Sites | 2015/05/20 | $200,000* |
| RP160013 | Visualizing T-cell trafficking | RES | Kundra, Vikas | The University of Texas M.D. Anderson Cancer Center | Skin | 2015/11/19 | $900,000 |
| RP160015 | Collaborative Training of a New Cadre of Innovative Cancer Prevention Researchers | RES | Ness, Roberta | The University of Texas Health Science Center at Houston | 2015/11/19 | $4,000,000 | |
| RP160019 | An Adaptive Personalized Clinical Trial using a Patient-Derived Xenograft Strategy to Overcome Ibrutinib Resistance in Mantle Cell Lymphoma | RES | Wang, Michael | The University of Texas M.D. Anderson Cancer Center | Lymphoma | 2015/11/19 | $841,606 |
| RP160022 | Role of Cohesin in Hematopoiesis and Myeloid Leukemia in Children with Down Syndrome | RES | Pati, Debananda | Baylor College of Medicine | Leukemia | 2015/11/19 | $1,905,638 |
| RP160023 | Investigating the genetic and molecular mechanisms underlying RAS/ERK substrate network | RES | Arur, Swathi | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/11/19 | $900,000 |
| RP160030 | A Randomized Controlled Trial (RCT) of Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System | RES | Gerber, David E | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2015/11/19 | $1,492,616 |
| RP160035 | The role of Prdm16 and histone H3 lysine 9 methyltransferase complex in MDS | RES | Nakada, Daisuke | Baylor College of Medicine | Leukemia | 2015/11/19 | $872,157 |
| RP160051 | Improving contrast for antibody-based tumor detection using PET | RES | Ward, Elizabeth S | Texas A&M University System Health Science Center | Bladder, Bone, Breast, Colorectal, Endocrine, Gallbladder, Head and Neck, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct, Lung and Bronchus, Lymphoma, Ovary, Pancreas, Prostate, Small Intestine, Stomach, Thyroid | 2015/11/19 | $887,134 |
| RP160054 | The CTC Circulator Phenotype: Insights into Mechanisms of Breast Cancer Dormancy | RES | Marchetti, Dario | Baylor College of Medicine | Brain and Other Nervous System, Breast | 2015/11/19 | $884,332 |
| RP160089 | Carbamoyl Phosphate Synthase-1: A new metabolic liability in non-small cell lung cancers | RES | DeBerardinis, Ralph J | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2015/11/19 | $900,000 |
| RP160097 | Cancer Prevention Post-Graduate Training Program in Integrative Epidemiology | RES | Spitz, Margaret R | Baylor College of Medicine | 2015/11/19 | $2,986,890 | |
| RP160121 | Clinical Safety and Efficacy of Third party, fucosylated, cord blood derived regulatory T cells to prevent graft versus host disease | RES | Parmar, Simrit | The University of Texas M.D. Anderson Cancer Center | Leukemia, Lymphoma, Myeloma | 2015/11/19 | $891,714 |
| RP160124 | Chemoprevention of Colon Cancer by Anti-inflammatory Blockade Using Neem | RES | Wargovich, Michael J | The University of Texas Health Science Center at San Antonio | Colorectal | 2015/11/19 | $899,617 |
| RP160145 | Early Detection of Ovarian Cancer with Tumor Associated Proteins and Autoantibodies | RES | Bast, Robert | The University of Texas M.D. Anderson Cancer Center | Ovary | 2015/11/19 | $1,487,303 |
| RP160150 | Radiogenomic Screen to Identify Novel Proliferation-associated Glioblastoma Genomic Therapeutic Targets: Discovery and Mechanistic Validation Study | RES | Colen, Rivka R | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2015/11/19 | $897,627 |
| RP160157 | Cancer Intervention and Prevention Discoveries Program | RES | Cobb, Melanie H | The University of Texas Southwestern Medical Center | 2015/11/19 | $3,993,250 | |
| RP160169 | Molecular Mechanism of NLRP12-mediated Regulation of Colorectal Cancer | RES | Zaki, Hasan | The University of Texas Southwestern Medical Center | Colorectal | 2015/11/19 | $897,707 |
| RP160180 | Development of Therapeutics Targeting Truncated Adenomatous Polyposis Coli (APC) as a Novel Prevention and Intervention Strategy for Colorectal Cancer | RES | Shay, Jerry W | The University of Texas Southwestern Medical Center | Colorectal | 2015/11/19 | $900,000 |
| RP160183 | Exploiting molecular and metabolic dependencies to optimize personalized therapeutic approaches for melanomas | RES | Davies, Michael A | The University of Texas M.D. Anderson Cancer Center | Skin | 2015/11/19 | $900,000 |
| RP160188 | Regulation of infiltration and function of tumor-resident CD8 T cells by IL-15 | RES | Schluns, Kimberly S | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/11/19 | $828,060 |
| RP160190 | Pediatric Radiation Oncology with Movie Induced Sedation Effect (PROMISE) | RES | Jiang, Steve | The University of Texas Southwestern Medical Center | All Sites | 2015/11/19 | $900,000 |
| RP160192 | Decoding Cellular Heterogeneity of Malignant Glioma | RES | Deneen, Benjamin | Baylor College of Medicine | Brain and Other Nervous System | 2015/11/19 | $899,701 |
| RP160211 | Novel tumorigenic mechanisms of the LKB1 tumor suppressor in endometrial and cervical cancer | RES | Castrillon, Diego H | The University of Texas Southwestern Medical Center | Cervix Uteri | 2015/11/19 | $896,653 |
| RP160229 | Imaging-based quantitative analysis of vascular perfusion and tissue oxygenation to improve therapy of hepatocellular carcinoma | RES | Avritscher, Rony | The University of Texas M.D. Anderson Cancer Center | All Sites | 2015/11/19 | $885,901 |
| RP160232 | Understanding Biological and Physical Factors Affecting Response to Proton Therapy to Improve its Clinical Effectiveness | RES | Mirkovic, Dragan | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System, Head and Neck, Lung and Bronchus | 2015/11/19 | $879,362 |
| RP160235 | Regulation of tumor aggressiveness and immune suppression in lung adenocarcinoma | RES | Liu, Qingyun | The University of Texas Health Science Center at Houston | Lung and Bronchus | 2015/11/19 | $900,000 |
| RP160237 | A novel epigenetic reader as therapeutic target in MLL-translocated pediatric leukemias | RES | Shi, Xiaobing | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2015/11/19 | $900,000 |
| RP160242 | Mechanisms and targeting strategies for SWI/SNF mutations in cancer | RES | Shen, Xuetong | The University of Texas M.D. Anderson Cancer Center | Breast, Gallbladder, Liver and Intrahepatic Bile Duct, Ovary, Pancreas, Prostate | 2015/11/19 | $900,000 |
| RP160249 | DIS3L2 in Childhood Wilms Tumor: Mechanism to Medicines | RES | Mendell, Joshua | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2015/11/19 | $1,200,000 |
| RP160255 | Structural and Functional Analyses of the Spindle Checkpoint | RES | Luo, Xuelian | The University of Texas Southwestern Medical Center | All Sites | 2015/11/19 | $900,000* |
| RP160268 | DNA damage-induced small non-coding RNAs: mechanism and their role in cancer development | RES | Liu, Yi | The University of Texas Southwestern Medical Center | All Sites | 2015/11/19 | $900,000 |
| RP160283 | Baylor College of Medicine Comprehensive Cancer Training Program | RES | Rosen, Jeffrey M | Baylor College of Medicine | 2015/11/19 | $3,986,268* | |
| RP160307 | Targeting Metastatic Pathways | RES | Terada, Lance S | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2015/11/19 | $900,000 |
| RP160318 | Role of Long Non-Coding RNAs in Breast Cancer: Identification, Characterization, and Determination of Molecular Functions | RES | Kraus, W. Lee | The University of Texas Southwestern Medical Center | Breast | 2015/11/19 | $886,652 |
| RP160319 | Role of PARP-1 in Estrogen Receptor Enhancer Function and Gene Regulation Outcomes in Breast Cancers | RES | Kraus, W. Lee | The University of Texas Southwestern Medical Center | Breast | 2015/11/19 | $884,315 |
| RP160340 | The role of the Lats kinases in sarcomatoid renal cell carcinoma | RES | Carroll, Thomas J | The University of Texas Southwestern Medical Center | Bladder, Kidney and Renal Pelvis, Lung and Bronchus | 2015/11/19 | $899,598 |
| RP160345 | Engineering T cells to ensure specificity for tumor cells and their environment | RES | Brenner, Malcolm K | Baylor College of Medicine | Leukemia, Lymphoma, Myeloma | 2015/11/19 | $900,000 |
| RP160384 | Promoting The Functions of Memory T cells for Adoptive T cell Therapy | RES | Wang, Jin | The Methodist Hospital Research Institute Prev. Org: Baylor College of Medicine Expended at Prev. Org: $47,170.74 | All Sites | 2015/11/19 | $840,505.26 |
| RP160440 | Targeting the undruggable: a first-in-class inhibitor of the HIF-2 transcription factor | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2015/11/19 | $899,412 |
| RP160451 | Protein Truncation Mutations in WIP1: Effects on Cancer and Hematopoiesis | RES | Donehower, Lawrence A | Baylor College of Medicine | Leukemia, Lymphoma, Sarcoma | 2015/11/19 | $900,000 |
| RP160460 | High resolution imaging for early and better detection of bladder cancer | RES | Richards-Kortum, Rebecca R | Rice University | Bladder | 2015/11/19 | $873,765* |
| RP160462 | Systematic identification of small molecule inhibitors that manipulate telomerase activities | RES | Songyang, Zhou | Baylor College of Medicine | All Sites | 2015/11/19 | $898,288 |
| RP160471 | Identifying new epigenetic vulnerabilities in pancreatic cancer | RES | Draetta, Giulio F | The University of Texas M.D. Anderson Cancer Center | Pancreas | 2015/11/19 | $900,000 |
| RP160482 | Nanoparticle Targeted STAT3 Immune Expression | RES | Heimberger, Amy B | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2015/11/19 | $888,429 |
| RP160487 | Cytokine signaling in Ewing sarcoma | RES | Shiio, Yuzuru | The University of Texas Health Science Center at San Antonio | Bone, Sarcoma | 2015/11/19 | $1,200,000 |
| RP160493 | Characterization and pharmacological targeting of the oncogenic activity of Jumonji enzymes | RES | Martinez, Elisabeth | The University of Texas Southwestern Medical Center | All Sites | 2015/11/19 | $899,997 |
| RP160497 | Amplified gold nanoparticle-mediated radiosensitization of tumors | RES | Krishnan, Sunil | The University of Texas M.D. Anderson Cancer Center | Head and Neck | 2015/11/19 | $899,309 |
| RP160501 | De-Orphanizing TLX: Implications for Glioblastomas | RES | Pownall, Henry | The Methodist Hospital Research Institute | Brain and Other Nervous System | 2015/11/19 | $878,969 |
| RP160512 | Integrin-mediated IL-18 signaling in the prevention and treatment of inflammation-associated colorectal cancer | RES | Dube, Peter | The University of Texas Health Science Center at San Antonio | Colorectal | 2015/11/19 | $859,620 |
| RP160517 | Exosomal DNA as a surrogate biomarker for early diagnosis and therapeutic stratification in pancreatic cancer | RES | Maitra, Anirban | The University of Texas M.D. Anderson Cancer Center | Pancreas | 2015/11/19 | $891,938 |
| RP160520 | Effect of Chest Radiation Therapy on Cardiomyocyte Turnover | RES | Sadek, Hesham | The University of Texas Southwestern Medical Center | All Sites | 2015/11/19 | $897,570 |
| RP160577 | A novel function of Itch in controlling IL-17-induced inflammation in colon cancer | RES | Poojary, Venuprasad K | Baylor Research Institute | Colorectal | 2015/11/19 | $900,000 |
| RP160589 | Arylhydrocarbon receptor mediated modulation of colorectal cancer by microbiota metabolites | RES | Chapkin, Robert S | Texas Agrilife Research | Colorectal | 2015/11/19 | $890,840 |
| RP160617 | Optimizing therapeutic strategies against lung cancer using Multi-Modality Imaging | RES | Zhang, Li | The University of Texas at Dallas | Lung and Bronchus | 2015/11/19 | $899,999 |
| RP160622 | Computational live cell histology | RES | Danuser, Gaudenz | The University of Texas Southwestern Medical Center | Skin | 2015/11/19 | $392,779 |
| RP160652 | Defining and Defeating Mechanistic Subtypes of KRAS-mutant Lung Cancers | RES | Kurie, Jonathan M | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2016/05/18 | $5,981,040 |
| RP160657 | Targeted Therapeutic Drug Discovery & Development Program | RES | Dalby, Kevin N | The University of Texas at Austin | All Sites | 2016/05/18 | $4,982,636 |
| RP160661 | Towards Carbon Beam Stereotactic Body Radiation Therapy (C-SBRT) for Higher Risk Early Stage Lung Cancer | RES | Jiang, Steve | The University of Texas Southwestern Medical Center | Lung and Bronchus | 2016/08/17 | $4,103,894 |
| RP160667 | DNA-Protein Crosslink Repair Pathways and Cancer Therapy | RES | Chen, Junjie | The University of Texas M.D. Anderson Cancer Center | All Sites | 2016/08/17 | $5,101,316 |
| RP160668 | Pathogenesis and Early Progression of Lung Cancer | RES | Wistuba, Ignacio | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2016/05/18 | $4,606,275 |
| RP160674 | Comparative Effectiveness Research on Cancer in Texas (CERCIT) 2.0 | RES | Goodwin, James | The University of Texas Medical Branch at Galveston | Bladder, Bone, Brain and Other Nervous System, Breast, Cervix Uteri, Colorectal, Corpus and Uterus, NOS, Endocrine, Esophagus, Eye and Orbit, Head and Neck, Kidney and Renal Pelvis, Lung and Bronchus, Ovary, Pancreas, Penis, Prostate, Sarcoma, Skin, Small Intestine, Stomach, Testis, Thyroid, Vagina, Vulva | 2016/08/17 | $6,000,000 |
| RP160693 | Acute Myeloid Leukemia in the Immunosuppressed Microenvironment | RES | Andreeff, Michael | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2016/08/17 | $6,000,000 |
| RP160704 | High affinity therapeutic mimotope antibodies to the oncogenic Epidermal Growth Factor Receptor | RES | Tucker, Haley O | The University of Texas at Austin | Leukemia, Lymphoma | 2016/05/18 | $200,000 |
| RP160710 | A Randomized Clinical Trial Platform with Translational Studies to Overcome Resistance in Triple Negative Breast Cancer | RES | Symmans, William | The University of Texas M.D. Anderson Cancer Center | Breast | 2016/08/17 | $5,997,677 |
| RP160713 | Amino Acid Sensing: Directing Cell Growth through mTORC1 | RES | Jewell, Jenna L | The University of Texas Southwestern Medical Center | All Sites | 2016/05/18 | $198,983 |
| RP160716 | Texas Pediatric Patient Derived Xenograft Facility | RES | Houghton, Peter J | The University of Texas Health Science Center at San Antonio | All Sites | 2016/05/18 | $5,079,843 |
| RP160732 | UTHSCSA Cancer Genome Sequencing and Computation Core | RES | Chen, Yidong | The University of Texas Health Science Center at San Antonio | All Sites | 2016/05/18 | $3,680,756 |
| RP160739 | Targeting Histone Acetylation Readers in MLL-translocated Leukemias | RES | Shi, Xiaobing | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2016/05/18 | $200,000 |
| RP160763 | Targeting multiple myeloma stem cell niche | RES | McCarty, Nami | The University of Texas Health Science Center at Houston | Myeloma | 2016/05/18 | $200,000 |
| RP160765 | An unlikely therapeutic target for malignant bone disease: Dkk-1 activates a stress resistance mechanism in bone tumor cells | RES | Gregory, Carl A | Texas A&M University System Health Science Center | Bone, Breast, Myeloma, Prostate | 2016/05/18 | $200,000 |
| RP160770 | Optical opening of blood-brain barrier for brain tumor drug delivery by plasmonic nanobubbles | RES | Qin, Zhenpeng | The University of Texas at Dallas | Brain and Other Nervous System | 2016/05/18 | $200,000 |
| RP160771 | The Adolescent and Childhood Cancer Epidemiology and Susceptibility Service (ACCESS) for Texas | RES | Scheurer, Michael | Baylor College of Medicine | All Sites | 2016/08/17 | $6,000,000 |
| RP160775 | Becoming fatter to survive: cancer cells increase lipid storage to counter metabolic stress | RES | Du, Guangwei | The University of Texas Health Science Center at Houston | All Sites | 2016/05/18 | $200,000 |
| RP160776 | Rapid Molecular Diagnosis of Lung Cancer Biopsies by Ambient Ionization Mass Spectrometry | RES | Schiavinato Eberlin, Livia | The University of Texas at Austin | Lung and Bronchus | 2016/05/18 | $200,000 |
| RP160795 | A "Pap smear" for ovarian cancer | RES | Yen, Laising | Baylor College of Medicine | Ovary | 2016/05/18 | $200,000 |
| RP160805 | Preclinical Candidate Discovery Core | RES | Matzuk, Martin M | Baylor College of Medicine | All Sites | 2016/05/18 | $5,999,997 |
| RP160806 | Development of high throughput technology to identify drugs for muscle wasting during cancer | RES | Vanapalli, Siva | Texas Tech University | Colorectal, Lung and Bronchus, Pancreas, Small Intestine | 2016/05/18 | $199,995 |
| RP160813 | Nanoparticle Prophylaxis for Protection from Chemotherapy Ototoxicity | RES | Chatterjee, Dev | Acelerox | Brain and Other Nervous System, Head and Neck, Lymphoma | 2016/05/18 | $195,665 |
| RP160819 | Quantitative mapping of intracellular protein-protein interactomes in healthy and cancerous cells | RES | Pellois, Jean-Philippe | Texas Agrilife Research | All Sites | 2016/05/18 | $198,753 |
| RP160822 | Exploring Geminivirus-encoded suppressor of histone methyltransferases as an anti-cancer drug | RES | Zhang, Xiuren | Texas Agrilife Research | Leukemia, Prostate | 2016/05/18 | $199,958 |
| RP160827 | A platform technology for the isolation of anti-cancer monoclonal antibodies from chickens | RES | Chen, Zhilei | Texas A&M University System Health Science Center | All Sites | 2016/05/18 | $200,000 |
| RP160834 | Integrated-cavity-enhanced pre-screening for lung cancer | RES | Yakovlev, Vladislav | Texas A&M University | Lung and Bronchus | 2016/05/18 | $200,000 |
| RP160841 | Targeting EWS-FLI-1 for degradation | RES | Shiio, Yuzuru | The University of Texas Health Science Center at San Antonio | Sarcoma | 2016/05/18 | $200,000 |
| RP160842 | Novel roles for NIK in high-grade glioma: regulation of mitochondrial dynamics to control cell migration and invasion | RES | Sitcheran, Raquel | Texas A&M University System Health Science Center | Brain and Other Nervous System | 2016/05/18 | $200,000 |
| RP160844 | Center for Innovative Drug Discovery: Enhancement of a Shared Cancer Resource for South Texas | RES | McHardy, Stanton | The University of Texas at San Antonio | All Sites | 2016/08/17 | $4,598,728 |
| RP160847 | A Body Coil for MR Imaging and Spectroscopy of Cancer at 7 Tesla | RES | Wright, Steven M | Texas A&M Engineering Experiment Station | Breast, Gallbladder, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct, Pancreas, Prostate | 2016/05/18 | $200,000 |
| RP160852 | Chemo-preventive Approach to Cancer Exploiting a Presumptive Link between Genomic Instability and Structural Stability of non-B DNA Sequences | RES | Kerwin, Sean M | Texas State University | All Sites | 2016/05/18 | $200,000 |
| RP160866 | Renal Clearable Nanodelivery System for Triple Negative Breast Cancer Therapy | RES | Zheng, Jie | The University of Texas at Dallas | Breast | 2016/05/18 | $200,000 |
| RP160884 | RNA processing stress: a new therapeutic entry point in triple-negative breast cancer | RES | Westbrook, Thomas | Baylor College of Medicine | Breast | 2016/05/18 | $200,000 |
| RP170002 | The University of Texas MD Anderson Science Park Next-Generation Sequencing Facility | RES | Shen, Jianjun | The University of Texas M.D. Anderson Cancer Center | Bladder, Brain and Other Nervous System, Breast, Childhood and Adolescent, Leukemia, Pancreas, Prostate | 2016/09/14 | $5,000,000 |
| RP170003 | North Texas Clinical Pharmacology Cancer Core | RES | Putnam, William | Texas Tech University Health Sciences Center | All Sites | 2016/09/14 | $2,499,900 |
| RP170005 | Proteomics and Metabolomics Core Facility | RES | Edwards, Dean P | Baylor College of Medicine | All Sites | 2016/09/14 | $5,000,000 |
| RP170040 | Exploiting DNA repair defects using intensity modulated proton therapy | RES | Sawakuchi, Gabriel | The University of Texas M.D. Anderson Cancer Center | All Sites | 2016/11/16 | $899,889 |
| RP170066 | Oncolytic Immunotherapy for Gliomas and Cancer Metastases in the Era of Checkpoint Regulation | RES | Fueyo, Juan | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System, Breast, Lung and Bronchus, Melanoma | 2016/11/16 | $990,905 |
| RP170067 | The Future of Cancer Research: Training Program for Basic and Translational Scientists | RES | Keyomarsi, Khandan | The University of Texas M.D. Anderson Cancer Center | 2016/11/16 | $4,000,000 | |
| RP170071 | Genetic Epidemiology and Molecular Basis of Cancer Predisposition in Pediatric Rhabdomyosarcoma | RES | Lupo, Philip | Baylor College of Medicine | Sarcoma | 2016/11/16 | $1,488,105 |
| RP170074 | Molecular Epidemiology And Somatic Alterations Driving Acute Lymphoblastic Leukemia In Down Syndrome | RES | Rabin, Karen | Baylor College of Medicine | Leukemia | 2016/11/16 | $1,200,000 |
| RP170079 | Palbociclib synergizes with autophagy inhibitors to induce senescence in breast cancer | RES | Keyomarsi, Khandan | The University of Texas M.D. Anderson Cancer Center | Breast | 2016/11/16 | $900,000 |
| RP170086 | Tumor suppression, p53 and retrotransposons | RES | Abrams, John M | The University of Texas Southwestern Medical Center | All Sites | 2017/08/16 | $816,171 |
| RP170090 | Novel Regulation and Function of TAK1 in Mutant Kras-driven Development of Pancreatic Ductal Adenocarcinoma | RES | Chiao, Paul | The University of Texas M.D. Anderson Cancer Center | Pancreas | 2017/08/16 | $823,500 |
| RP170095 | Exercise as an aid to smoking cessation in anxiety vulnerable adults | RES | Smits, Jasper | The University of Texas at Austin | Lung and Bronchus | 2016/11/16 | $891,623 |
| RP170114 | Mechanisms of melanoma metastasis | RES | Morrison, Sean | The University of Texas Southwestern Medical Center | Melanoma | 2016/11/16 | $892,521 |
| RP170126 | A Novel Pathway to Reduce BRCA1-Associated Breast Cancer Risk | RES | Hu, Yanfen | The University of Texas Health Science Center at San Antonio | Breast | 2016/11/16 | $900,000 |
| RP170144 | Effective Exploitation Of Structural Data For Oncology | RES | Ioerger, Thomas | Texas A&M Engineering Experiment Station | All Sites | 2016/11/16 | $900,000 |
| RP170146 | B cell receptor signaling intersects with angiogenesis in diffuse large B cell lymphoma | RES | Aguiar, Ricardo | The University of Texas Health Science Center at San Antonio | Leukemia, Lymphoma | 2016/11/16 | $632,160 |
| RP170152 | Targeting the HNF4A and WNT/Beta-catenin pathways in childhood malignant yolk sac tumors. | RES | Amatruda, James F | The University of Texas Southwestern Medical Center | Ovary, Testis | 2016/11/16 | $1,169,499 |
| RP170169 | High throughput combinatory drug screening for pediatric medulloblastomas with a dysregulated EZH2 pathway | RES | Li, Xiao-Nan | Baylor College of Medicine | Brain and Other Nervous System | 2016/11/16 | $1,198,726 |
| RP170170 | Prediction of nuclear export signals in proteins | RES | Grishin, Nick | The University of Texas Southwestern Medical Center | All Sites | 2016/11/16 | $844,989 |
| RP170172 | Targeting Therapy Resistance using Epithelial to Mesenchymal Transition (EMT) Pathways in Preclinical Claudin Low Breast Cancer Models | RES | Rosen, Jeffrey M | Baylor College of Medicine | Breast | 2017/08/16 | $823,500* |
| RP170179 | Chemoablation of High-Risk Oral Premalignant Lesions for Sustained Cancer Prevention | RES | Tsai, Robert | Texas A&M University System Health Science Center | Head and Neck | 2017/08/16 | $915,000 |
| RP170180 | Mechanistic Roles of Long Non-Coding RNA in Glioblastoma Development and Treatment | RES | Huang, Suyun | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2017/08/16 | $823,500 |
| RP170207 | BBB-penetrating redox-responsive smart drugs and exploiting the MGMT-driven S-phase checkpoint for chemotherapy of childhood brain cancers | RES | Srivenugopal, Kalkunte S | Texas Tech University Health Sciences Center | Brain and Other Nervous System | 2016/11/16 | $1,173,149 |
| RP170231 | Identifying vulnerabilities in mutant p53 driven tumorigenesis | RES | Lozano, Guillermina | The University of Texas M.D. Anderson Cancer Center | Bone, Breast | 2016/11/16 | $869,197 |
| RP170233 | K-ras Spatiotemporal Dynamics: Novel Therapeutic Targets | RES | Hancock, John F | The University of Texas Health Science Center at Houston | Colorectal, Lung and Bronchus, Melanoma, Pancreas | 2016/11/16 | $900,000 |
| RP170245 | Discovery of antibody-drug conjugates targeting a receptor broadly expressed in solid tumors | RES | Liu, Qingyun | The University of Texas Health Science Center at Houston | Breast, Colorectal, Ovary | 2016/11/16 | $1,000,000 |
| RP170259 | CPRIT Cancer Prevention Research Training Program | RES | Chang, Shine | The University of Texas M.D. Anderson Cancer Center | 2016/11/16 | $2,648,151 | |
| RP170267 | Chemically based disruption of oncogenic beta-catenin activity in liver tissue | RES | Zhu, Hao | The University of Texas Southwestern Medical Center | Gallbladder, Liver and Intrahepatic Bile Duct | 2017/08/16 | $823,500 |
| RP170295 | Developing Effective Epigenetic Biomarkers to Identify Individuals with High Risk of Cancer | RES | Waterland, Robert | Baylor College of Medicine | Bladder, Breast, Colorectal, Kidney and Renal Pelvis, Lung and Bronchus, Lymphoma, Prostate | 2016/11/16 | $1,052,089 |
| RP170301 | Osteopathic Scholars in Cancer Research (OSCR) | RES | Vishwanatha, Jamboor | University of North Texas Health Science Center at Fort Worth | 2016/11/16 | $799,055 | |
| RP170307 | BIOMARKER-BASED TREATMENT OF POOR PROGNOSTIC MESENCHYMAL SUBTYPE IN GASTRIC CANCER | RES | Lee, Ju-Seog | The University of Texas M.D. Anderson Cancer Center | Stomach | 2016/11/16 | $893,875 |
| RP170314 | Biodegradable nanoclusters for molecular cancer imaging | RES | Sokolov, Konstantin | The University of Texas M.D. Anderson Cancer Center | Ovary | 2016/11/16 | $899,553 |
| RP170317 | Developing Effective Immunotherapeutic Strategies for Advanced Uveal Melanoma | RES | Woodman, Scott | The University of Texas M.D. Anderson Cancer Center | Eye and Orbit | 2016/11/16 | $899,507 |
| RP170330 | A novel GRK3-EZH2 regulatory pathway in prostate cancer progression | RES | Li, Wenliang | The University of Texas Health Science Center at Houston | Lung and Bronchus, Prostate | 2016/11/16 | $900,000 |
| RP170333 | Targeting ubiquitination for cancer therapy | RES | Zhang, Shuxing | The University of Texas M.D. Anderson Cancer Center | Breast | 2017/08/16 | $915,000 |
| RP170345 | UTHSCSA Cancer Research Training Program | RES | Oyajobi, Babatunde | The University of Texas Health Science Center at San Antonio | 2016/11/16 | $3,996,895 | |
| RP170366 | Optimizing Chemoradiation Strategies by Tumor Metabolism Interrogation | RES | Lai, Stephen | The University of Texas M.D. Anderson Cancer Center | Head and Neck, Thyroid | 2016/11/16 | $899,996 |
| RP170373 | HTS for covalent GTP-competitive inhibitors of KRAS G12C | RES | Westover, Kenneth | The University of Texas Southwestern Medical Center | Colorectal, Lung and Bronchus, Pancreas | 2017/08/16 | $823,500 |
| RP170382 | Primary Cilia in Cell Cycle Control and Tumorigenesis | RES | Zhong, Qing | The University of Texas Southwestern Medical Center | Breast | 2016/11/16 | $900,000 |
| RP170387 | Development and Validation of a Network-guided, Multi-objective Optimization Model for Cancer Data Analysis. | RES | Liu, Zhandong | Baylor College of Medicine | All Sites | 2016/11/16 | $889,679 |
| RP170399 | Elimination of hypoxia sensitizes resistant solid tumors to immunotherapy | RES | Curran, Michael | The University of Texas M.D. Anderson Cancer Center | Prostate | 2016/11/16 | $899,993 |
| RP170401 | Targeting The Glycolysis Pathway To Overcome Resistance To Cancer Immunotherapy | RES | Hwu, Patrick | The University of Texas M.D. Anderson Cancer Center | Melanoma | 2016/11/16 | $900,000 |
| RP170407 | Role of HDAC8 and higher order chromatin structure in melanoma metastasis and therapy | RES | Rai, Kunal | The University of Texas M.D. Anderson Cancer Center | Skin | 2017/08/16 | $823,154 |
| RP170427 | Ambient Mass Spectrometry for Preoperative Molecular Diagnosis of Thyroid Fine Needle Aspirate Biopsies | RES | Schiavinato Eberlin, Livia | The University of Texas at Austin | Thyroid | 2016/11/16 | $983,586 |
| RP170466 | Targeting the Inflammatory Cancer Stem Cell Microenvironment of Triple Negative Breast Cancer with Leukocyte-mimetic Nanovesicles | RES | Tasciotti, Ennio | The Methodist Hospital Research Institute | Breast | 2016/11/16 | $896,951 |
| RP170470 | OCT4/c-MYC axis as a mechanism of resistance to 13-cis retinoic acid in neuroblastoma | RES | Kang, Min H | Texas Tech University Health Sciences Center | Brain and Other Nervous System | 2016/11/16 | $1,125,638 |
| RP170488 | Mechanisms of Notch Dysregulation in Pediatric Osteosarcoma | RES | Lee, Brendan | Baylor College of Medicine | Bone, Sarcoma | 2016/11/16 | $1,110,480 |
| RP170493 | For Our Children: A tailored multi-level intervention for parents and healthcare providers to increase HPV vaccination rates | RES | Fernandez, Maria E | The University of Texas Health Science Center at Houston | Cervix Uteri, Head and Neck, Penis, Vagina, Vulva | 2016/11/16 | $1,487,683 |
| RP170496 | Targeting a Growth and Survival Pathway in Bone Tumor Cells. | RES | Gregory, Carl A | Texas A&M University System Health Science Center | Bone, Breast, Myeloma, Prostate, Sarcoma | 2016/11/16 | $864,971 |
| RP170500 | Development of next generation steroid receptor coactivator small molecule inhibitors as novel agents to target therapy-resistant breast cancer | RES | O'Malley, Bert | Baylor College of Medicine | Breast | 2017/08/16 | $914,006 |
| RP170508 | Structural modeling of peptide-HLA complexes presenting a melanoma-associated antigen for cross-reactivity assessment | RES | Kavraki, Lydia | Rice University | Melanoma | 2016/11/16 | $900,000 |
| RP170510 | Telomere Maintenance Mechanisms in Neuroblastoma | RES | Reynolds, Charles | Texas Tech University Health Sciences Center | Brain and Other Nervous System | 2016/11/16 | $1,058,246 |
| RP170537 | Identification of novel immune targets and neoantigens for development of immunotherapy for breast cancer | RES | Wang, Rongfu | The Methodist Hospital Research Institute | Breast | 2016/11/16 | $999,995 |
| RP170564 | Super-resolution imaging of tumor angiogenesis in deep tissue with high specificity and sensitivity | RES | Yuan, Baohong | The University of Texas at Arlington | Breast, Colorectal, Head and Neck, Ovary, Prostate, Skin, Thyroid, Vagina | 2016/11/16 | $900,000 |
| RP170572 | Probing Novel Concepts of the NF-kappaB Transcriptional Program in Human Cancer | RES | D'Orso, Ivan | The University of Texas Southwestern Medical Center | All Sites | 2017/08/16 | $679,458 |
| RP170593 | Computational Cancer Biology Training Program | RES | Pettitt, B. Montgomery | The University of Texas Medical Branch at Galveston | 2016/11/16 | $3,999,285 | |
| RP170619 | An Unexpected Oncometabolic Axis: Exposing Novel Regulators of Cardiac Remodeling in Leukemia | RES | Taegtmeyer, Heinrich | The University of Texas Health Science Center at Houston | Leukemia | 2017/08/16 | $199,744 |
| RP170628 | The University of Texas M.D. Anderson Cancer Center Science Park Flow Cytometry and Cell Imaging Core | RES | Richie, Ellen | The University of Texas M.D. Anderson Cancer Center | All Sites | 2017/08/16 | $3,693,219 |
| RP170633 | The Role of the CACNA1D Calcium Channel in Melanoma | RES | Morrison, Sean | The University of Texas Southwestern Medical Center | Skin | 2017/08/16 | $199,828 |
| RP170638 | Cyclotron and Radiochemistry Core Facility for Pediatric Oncology | RES | Sun, Xiankai | The University of Texas Southwestern Medical Center | All Sites | 2017/08/16 | $5,648,027 |
| RP170640 | Capitalizing on Therapeutic Liabilities in RAS-Mutant Cancers With a Rational Combination Therapy With PARP and MEK Inhibitors | RES | Mills, Gordon B | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus, Pancreas, Skin | 2017/08/16 | $200,000 |
| RP170644 | Establish a New Cryo-Electron Microscopy Core Facility and Service for Structure Determination at UT Southwestern Medical Center | RES | Nicastro, Daniela | The University of Texas Southwestern Medical Center | All Sites | 2017/08/16 | $5,498,714 |
| RP170653 | Identify Streptococcus gallolyticus Factors Important for Promoting Colorectal Tumor Development | RES | Xu, Yi | Texas A&M University System Health Science Center | Colorectal | 2017/08/16 | $200,000 |
| RP170660 | Optogenetic Toolkit for Precise Epigenome Editing in Cancer Cells | RES | Zhou, Yubin | Texas A&M University System Health Science Center | All Sites | 2017/08/16 | $200,000 |
| RP170668 | Data Science and Informatics Core for Cancer Research | RES | Zheng, Wenjin | The University of Texas Health Science Center at Houston | All Sites | 2017/08/16 | $5,846,383 |
| RP170671 | Targeting a Novel Nuclease PAAN in Triple-Negative Breast Cancer | RES | Wang, Yingfei | The University of Texas Southwestern Medical Center | Breast | 2017/08/16 | $200,000 |
| RP170674 | Regulation of Cancer Cell Migration by Secreted Protein Phosphorylation | RES | Tagliabracci, Vincent S | The University of Texas Southwestern Medical Center | Breast | 2017/08/16 | $200,000 |
| RP170675 | Individualized Pediatric Tumor Analysis Center of Texas (INPACT) | RES | Allen, Carl | Baylor College of Medicine | All Sites | 2017/08/16 | $200,000* |
| RP170686 | A Novel Chemical Strategy to Target EGFR for Destruction | RES | Rao, Hai | The University of Texas Health Science Center at San Antonio | Breast, Lung and Bronchus, Thyroid | 2017/08/16 | $200,000 |
| RP170691 | Patient-Derived Xenograft and Advanced in Vivo Models (PDX-AIM) Core Facility | RES | Lewis, Michael | Baylor College of Medicine | All Sites | 2017/08/16 | $4,766,430 |
| RP170696 | Targeting Cathepsin L as a Selective Mechanism for the Release of Potent Anticancer Agents from Drug-Linker Conjugates | RES | Pinney, Kevin G | Baylor University | Pancreas | 2017/08/16 | $200,000 |
| RP170699 | Targeting a Metabolic Reprogramming Event for the Early Prevention of Pancreatic Cancers | RES | Tu, Benjamin P | The University of Texas Southwestern Medical Center | Pancreas | 2017/08/16 | $200,000 |
| RP170714 | Optimization of a Novel Class of Microtubule Stabilizers That Circumvent Multiple Drug Resistance Mechanisms Through Crystal-Structure Guided Total Synthesis | RES | Frantz, Douglas | The University of Texas at San Antonio | All Sites | 2017/08/16 | $200,000 |
| RP170719 | GCC Center for Advanced Microscopy and Image Informatics | RES | Mancini, Michael | Texas A&M University System Health Science Center | All Sites | 2017/08/16 | $5,793,075 |
| RP170721 | Enhancing Immunotherapy of Pancreatic Cancer by Disrupting Mutant K-Ras Using CRISPR/Cas9 | RES | Bao, Gang | Rice University | Pancreas | 2017/08/16 | $200,000 |
| RP170722 | Identification of Critical Dependencies and Actionable Therapeutic Options in Smarcb1-Deficient Pediatric Tumors | RES | Draetta, Giulio | The University of Texas M.D. Anderson Cancer Center | Gallbladder, Kidney and Renal Pelvis, Liver and Intrahepatic Bile Duct | 2017/08/16 | $200,000 |
| RP170734 | Mitochondrial DNA Instability Engages a Cancer-Related Interferon Program to Modify the Immune Microenvironment and NAD+ Metabolome and Enhance Melanoma Growth | RES | West, Andrew | Texas A&M University System Health Science Center | Skin | 2017/08/16 | $199,795 |
| RP170747 | Noninvasive Lung Cancer Screening by Rapid Chemical Profiling of Exhaled Breath | RES | Sun, Yuze | The University of Texas at Arlington | Lung and Bronchus | 2017/08/16 | $199,999 |
| RP170752 | Radiation-Induced Release of Chemotherapeutic Agents in Vivo | RES | Gassensmith, Jeremiah | The University of Texas at Dallas | All Sites | 2017/08/16 | $200,000 |
| RP170797 | The Preparation of Novel Phage-Displayed Macrocyclic Peptide Libraries for the Identification of Anticancer Agents | RES | Liu, Wenshe | Texas A&M University | Breast, Colorectal, Prostate | 2017/08/16 | $200,000 |
| RP170805 | Etiology and Prevention of Gastric Cancers by Mitigation of H pylori Mechanosensing | RES | Lele, Pushkar | Texas A&M Engineering Experiment Station | Stomach | 2017/08/16 | $200,000 |
| RP170817 | Isolation and in Situ Profiling of Circulating Tumor Cell Subpopulations Using a Hyperuniform Structured Microchip | RES | Li, Wei | Texas Tech University | All Sites | 2017/08/16 | $200,000 |
| RP180031 | Imaging of biochemical alterations in human breast malignancy using CEST-MRI | RES | Vinogradov, Elena | The University of Texas Southwestern Medical Center | Breast | 2018/02/21 | $900,000* |
| RP180047 | A Novel Dual Suppressor of Cancer Bone Metastasis | RES | Wan, Yihong | The University of Texas Southwestern Medical Center | Bone, Breast | 2018/02/21 | $898,672* |
| RP180055 | Mechanisms and Treatment of Hippocampal Cognitive Impairment Associated with Androgen Deprivation Therapy for Prostate Cancer | RES | Morilak, David A | The University of Texas Health Science Center at San Antonio | Prostate | 2018/02/21 | $899,547* |
| RP180073 | Myeloid support of refractory and aggressive T-ALL at distinct tumor sites | RES | Ehrlich, Lauren | The University of Texas at Austin | Leukemia, Lymphoma | 2018/02/21 | $1,200,000* |
| RP180131 | DNA methylation signatures of cell-free DNA in CSF as a new response biomarker for pediatric medulloblastoma | RES | Sun, Deqiang | Texas A&M University System Health Science Center | Brain and Other Nervous System | 2018/02/21 | $1,200,000* |
| RP180140 | EXTernal beam radiation to Eliminate Nominal metastatic Disease (EXTEND): A randomized phase II basket trial to assess local control of oligometastatic disease | RES | Tang, Chad | The University of Texas M.D. Anderson Cancer Center | All Sites | 2018/02/21 | $2,394,412* |
| RP180147 | Prevalence of Rare Passenger Mutations in Biopsy Tissue as Cancer Stratification Markers | RES | Zhang, David | Rice University | All Sites | 2018/02/21 | $900,000* |
| RP180166 | Molecular mechanisms of anthracycline response in cardiomyocytes and link to genetic susceptibility to cardiotoxicity in long-term childhood cancer survivors | RES | Hildebrandt, Michelle | The University of Texas M.D. Anderson Cancer Center | All Sites | 2018/02/21 | $1,194,520* |
| RP180177 | Novel Small Molecule Probes Targeting Histone Acetyltransferase p300/CBP | RES | Song, Yongcheng | Baylor College of Medicine | Leukemia | 2018/02/21 | $900,000* |
| RP180178 | Imaging glucose stimulated zinc secretion (GSZS) from the prostate by MRI: A potentially powerful method for early detection of prostate cancer | RES | Sherry, Dean | The University of Texas Southwestern Medical Center | Prostate | 2018/02/21 | $900,000* |
| RP180181 | Targeting neutrophil elastase as a novel therapy for metastatic breast cancer | RES | Watowich, Stephanie | The University of Texas M.D. Anderson Cancer Center | Breast | 2018/02/21 | $900,000* |
| RP180191 | Understanding TFE3-mediated Tumorigenesis through Analysis of a Novel, Clinically-Relevant Mouse Model of Translocation Renal Cell Carcinoma | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2018/02/21 | $1,155,128* |
| RP180192 | Dissecting the interplay between BAP1 and PBRM1 in renal cancer | RES | Brugarolas, James | The University of Texas Southwestern Medical Center | Kidney and Renal Pelvis | 2018/02/21 | $897,633* |
| RP180196 | Microwafers as Novel Drug or Gene Delivery Vehicles for Noninvasive Treatment of Retinoblastoma | RES | Hurwitz, Richard | Baylor College of Medicine | Eye and Orbit | 2018/02/21 | $1,195,721* |
| RP180220 | Targeting the prion protein Doppel in brain tumor angiogenesis | RES | McCarty, Joseph | The University of Texas M.D. Anderson Cancer Center | Brain and Other Nervous System | 2018/02/21 | $900,000* |
| RP180244 | Functional analyses of linkage-specific ubiquitination in the DNA damage response | RES | Wang, Bin | The University of Texas M.D. Anderson Cancer Center | All Sites | 2018/02/21 | $900,000* |
| RP180248 | Characterizing cancer genome instability and translational impact using new sequencing technologies | RES | Chen, Ken | The University of Texas M.D. Anderson Cancer Center | All Sites | 2018/02/21 | $898,997* |
| RP180259 | PTEN Promotes Diabetic breast cancer metastasis | RES | Lin, Chunru | The University of Texas M.D. Anderson Cancer Center | Breast | 2018/02/21 | $900,000* |
| RP180268 | Determining the role of polyploidization in liver cancer development | RES | Zhu, Hao | The University of Texas Southwestern Medical Center | Gallbladder, Liver and Intrahepatic Bile Duct | 2018/02/21 | $900,000* |
| RP180275 | Targeting Stromal ERalpha for Cervical Cancer Therapy | RES | Chung, Sang-Hyuk | University of Houston | Cervix Uteri | 2018/02/21 | $811,617* |
| RP180288 | Innate Immune Regulation of Cancer Cell Proliferation | RES | Yan, Nan | The University of Texas Southwestern Medical Center | Lung and Bronchus, Skin | 2018/02/21 | $900,000* |
| RP180309 | Inhibiting Oxidative Phosphorylation: A Novel Strategy in Leukemia | RES | Konopleva, Marina | The University of Texas M.D. Anderson Cancer Center | Leukemia | 2018/02/21 | $900,000* |
| RP180313 | A somatic mutant p53 mouse model of metastatic triple negative breast cancer | RES | Lozano, Guillermina | The University of Texas M.D. Anderson Cancer Center | Breast | 2018/02/21 | $900,000* |
| RP180319 | Rhabdomyosarcoma vulnerabilities: Prioritizing and extending to the clinic | RES | Skapek, Stephen X | The University of Texas Southwestern Medical Center | Sarcoma | 2018/02/21 | $1,193,363* |
| RP180343 | Turn ON the Tumor Contrast in Lymph Node Metastases for Occult Disease Detection | RES | Gao, Jinming | The University of Texas Southwestern Medical Center | Breast, Head and Neck | 2018/02/21 | $885,684* |
| RP180349 | Therapeutics Targeting Cancer-Associated HPV Replication | RES | Chiang, Cheng-Ming | The University of Texas Southwestern Medical Center | Cervix Uteri, Head and Neck | 2018/02/21 | $900,000* |
| RP180381 | Mass Spectrometry Imaging to Uncover Predictive Metabolic Markers of Ovarian Cancer Surgical Outcome and Treatment Response | RES | Schiavinato Eberlin, Livia | The University of Texas at Austin | Ovary | 2018/02/21 | $1,092,048* |
| RP180394 | Targeting the metastatic sarcoma niche using leukocyte biomimetic nanoparticles | RES | Tasciotti, Ennio | The Methodist Hospital Research Institute | Bone, Sarcoma | 2018/02/21 | $1,199,617* |
| RP180404 | Noninvasive detection of anthracycline induced cardiotoxicity using hyperpolarized carbon 13 based magnetic resonance spectroscopic imaging | RES | Zaha, Vlad | The University of Texas Southwestern Medical Center | Breast | 2018/02/21 | $2,397,204* |
| RP180410 | Mechanisms of Nuclear Export in Cancer | RES | Chook, Yuh Min | The University of Texas Southwestern Medical Center | All Sites | 2018/02/21 | $900,000* |
| RP180435 | Fasting-induced inhibition of leukemia development | RES | Zhang, Chengcheng | The University of Texas Southwestern Medical Center | Leukemia | 2018/02/21 | $900,000* |
| RP180457 | Tumor Activated Enzyme Inhibitors for the Treatment of Cancer | RES | Ready, Joseph M | The University of Texas Southwestern Medical Center | Gallbladder, Liver and Intrahepatic Bile Duct, Lung and Bronchus | 2018/02/21 | $898,776* |
| RP180463 | Compound heterozygous mutations in pediatric cancer predisposition | RES | Schlacher, Katharina | The University of Texas M.D. Anderson Cancer Center | Head and Neck, Leukemia, Vagina | 2018/02/21 | $556,763* |
| RP180466 | Integrated single-cell biomarkers of T-cell efficacy | RES | Varadarajan, Navin | University of Houston | Lymphoma | 2018/02/21 | $1,173,420* |
| RP180472 | Mucosal vaccine formulations for targeted therapy of HPV cancers | RES | Sastry, Jagannadha | The University of Texas M.D. Anderson Cancer Center | Cervix Uteri, Head and Neck, Vagina | 2018/02/21 | $883,146* |
| RP180473 | Clinical trials of C188-9, an oral inhibitor of signal transducer and activator of transcription (STAT) 3, in patients with hepatocellular carcinoma (HCC) | RES | Tweardy, David J | The University of Texas M.D. Anderson Cancer Center | Gallbladder, Liver and Intrahepatic Bile Duct | 2018/02/21 | $2,399,905* |
| RP180504 | Elucidating the Epigenetic and Metabolic Vulnerabilities of Myeloproliferative Neoplasms | RES | Xu, Jian | The University of Texas Southwestern Medical Center | Leukemia | 2018/02/21 | $900,000* |
| RP180505 | Circulating Exosomes as Biomarkers for Lung Cancer Early Detection | RES | Taguchi, Ayumu | The University of Texas M.D. Anderson Cancer Center | Lung and Bronchus | 2018/02/21 | $799,085* |
| RP180530 | Hippo signaling in non-alcoholic fatty liver disease (NAFLD) and it progression to hepatocellular carcinoma | RES | Johnson, Randy | The University of Texas M.D. Anderson Cancer Center | Gallbladder, Liver and Intrahepatic Bile Duct | 2018/02/21 | $821,669* |
| RP180553 | Structural and Functional Characterization of the DNA Double Strand Break Processing Complex of Mre11-Rad50 | RES | Latham, Michael | Texas Tech University | Breast, Colorectal, Prostate | 2018/02/21 | $850,876* |
| RP180588 | Novel Computer Aided Diagnosis System For Early Detection Of Oral Cancer Based On Quantitative Autofluorescence Imaging | RES | Jo, Javier | Texas A&M Engineering Experiment Station | Head and Neck | 2018/02/21 | $897,394* |
| RP180590 | Development of an engineered & pharmacologically optimized human methionine-gamma-lyase drug candidate for the treatment of prostate cancer and glioblastoma | RES | Stone, Everett | The University of Texas at Austin | Brain and Other Nervous System, Prostate | 2018/02/21 | $900,000* |
| RP180607 | Blood-based biomarkers for the early detection of pancreatic cancer | RES | Killary, Ann | The University of Texas M.D. Anderson Cancer Center | Pancreas | 2018/02/21 | $900,000* |
| RP180634 | Understanding metabolic regulation of pediatric glioma through mouse modeling and patient tumor interrogation in vivo. | RES | Bachoo, Robert | The University of Texas Southwestern Medical Center | Brain and Other Nervous System | 2018/02/21 | $1,200,000* |
